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Publikováno v:
Biochemical pharmacology. 169
Lipocalin-2 (LCN2), also known as 24p3 and neutrophil gelatinase-associated lipocalin (NGAL), is a 25-kDa secreted protein implicated in various metabolic and inflammatory diseases. Early studies suggest the protective function of LCN2 in which it ac
Autor:
Habibur Rahman, Won-Ha Lee, Mithilesh Kumar Jha, Hyun Kook, Inkyu Lee, Dong Ho Park, Kyoungho Suk
Publikováno v:
Journal of Neuroscience Research. 94:837-849
Pyruvate dehydrogenase (PDH) kinases (PDKs) 1-4, expressed in peripheral and central tissues, regulate the activity of the PDH complex (PDC). The PDC is an important mitochondrial gatekeeping enzyme that controls cellular metabolism. The role of PDKs
Publikováno v:
Biochemical pharmacology. 103
Recent neuroscience research has established the adult brain as a dynamic organ having a unique ability to undergo changes with time. Neuroglia, especially microglia and astrocytes, provide dynamicity to the brain. Activation of these glial cells is