Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ye Zheng"'
Autor:
Yuqiong Liang, Michael Downes, Theodore M. Kamenecka, Ruth T. Yu, Annette R. Atkins, Ye Zheng, Ronald M. Evans, Thomas P. Burris, Chin-San Loo, Laura A. Solt, Sagar P Bapat, Mathias Leblanc, Han Cho, Christina L. Chang, Xuan Zhao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Th17 cells are a subset of T cells that produce interleukin 17 and other proinflammatory cytokines. They are involved in the development of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. Previous studies illustr
Autor:
Rebecca S. LaRue, Louisa E. Sjaastad, Mark S. Anderson, Calvin B. Williams, Praful Aggarwal, Maria-Luisa Alegre, Ulrich Broeckel, Shawn A. Mahmud, Irina Proekt, Dimitre R. Simeonov, Jason B. Williams, Michael A. Farrar, Weishan Huang, Jonathan C. Jeschke, Corey N. Miller, Roland Ruscher, David L. Owen, Christine Henzler, Justin A. Spanier, Can Hekim, Avery August, Alexander Marson, Ye Zheng
Publikováno v:
Nature immunology
The developmental programs that generate a broad repertoire of regulatory T cells (Treg cells) able to respond to both self antigens and non-self antigens remain unclear. Here we found that mature Treg cells were generated through two distinct develo
Autor:
Joshua J. Coon, Gary M. Wilson, Ye Zheng, Jing Fan, Ruiqi Liao, Gretchen L. Seim, Yuannyu Zhang, Xin Liu, Jian Xu, Nobuyuki Tanimura, Sunduz Keles, Peiman Hematti, Emery H. Bresnick
Publikováno v:
Cell Reports, Vol 31, Iss 13, Pp 107832-(2020)
Cell Rep
Cell Rep
Summary: Protein ensembles control genome function by establishing, maintaining, and deconstructing cell-type-specific chromosomal landscapes. A plethora of small molecules orchestrate cellular functions and therefore may link physiological processes
Autor:
Chun-Ye Zheng, Xin-Chun Zhang, Hong-Feng Liang, Ying-Bin Li, Jun Cai, Xiao-xin Bai, Hua-Jun Wang, Ai-Ping Gu, Xialin Tang
Publikováno v:
Neuropharmacology. 158
Yin-Yang 1 (YY1) has been identified as playing critical roles in multiple diseases. However, little is known regarding its roles and mechanisms in cerebral ischemia/reperfusion (I/R) injury. This study is aimed to explore the roles of YY1 in regulat
Autor:
Mathias Leblanc, Christopher Liddle, Ronald M. Evans, Annette R. Atkins, Ruth T. Yu, Jae Myoung Suh, Yuqiong Liang, Ye Zheng, Michael Downes, Sihao Liu, Carmen Zhou, Sungsoon Fang, Yang Zhang, Albert Cheng, Sagar P. Bapat
Publikováno v:
Nature. 528:137-141
Age-associated insulin resistance (IR) and obesity-associated IR are two physiologically distinct forms of adult-onset diabetes. While macrophage-driven inflammation is a core driver of obesity-associated IR, the underlying mechanisms of the obesity-
Autor:
Yun Zhou, Jing Zhang, Charu Mehta, Kirby D. Johnson, Inga Hofmann, Jun Wu, Sunduz Keles, Kyunghee Choi, Alexandra A. Soukup, Peng Liu, Emery H. Bresnick, Miao Cao, Ye Zheng
Publikováno v:
The Journal of clinical investigation. 129(3)
The development and function of stem and progenitor cells that produce blood cells are vital in physiology. GATA-binding protein 2 (GATA2) mutations cause GATA-2 deficiency syndrome involving immunodeficiency, myelodysplastic syndrome, and acute myel
Autor:
Ruiqi Liao, Emery H. Bresnick, Yuannyu Zhang, Jian Xu, Joshua J. Coon, Nobuyuki Tanimura, Matthew R. Dent, Peiman Hematti, Gary M. Wilson, Ye Zheng, Xin Liu, Miao Cao, Judith N. Burstyn, Sunduz Keles
Publikováno v:
Developmental cell. 46(5)
By functioning as an enzyme cofactor, hemoglobin component, and gene regulator, heme is vital for life. One mode of heme-regulated transcription involves amplifying the activity of GATA-1, a key determinant of erythrocyte differentiation. To discover
Autor:
Jailal N. G. Ablack, Mark H. Ginsberg, Jack D. Bui, Kelly A. Remedios, John T. Chang, Patrick J. Metz, Li-Fan Lu, Joseph M. Cantor, Jane E. Klann, Zhaoren He, Jocelyn G. Olvera, Stephanie H. Kim, Justine Lopez, Brian G. Petrich, Tiffani Tysl, Gene W. Yeo, Ye Zheng, Brigid S. Boland
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 200(12)
Maintenance of the regulatory T (Treg) cell pool is essential for peripheral tolerance and prevention of autoimmunity. Integrins, heterodimeric transmembrane proteins consisting of α and β subunits that mediate cell-to-cell and cell-to-extracellula
Autor:
Jovan Shepherd, Yi Liu, Ye Zheng, Christian J. Maine, Guo Fu, Mohsen Sabouri-Ghomi, Changchun Xiao, Nengming Xiao, Seung Goo Kang, Cheng-Jang Wu, Shunbin Xu, Alicia Gonzalez-Martin, Li-Fan Lu, Zhe Huang, Wen Hsien Liu, Alexander Hoffmann, Hyun Yong Jin
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
The Journal of Experimental Medicine
The Journal of experimental medicine, vol 213, iss 9
instname
The Journal of Experimental Medicine
The Journal of experimental medicine, vol 213, iss 9
Xiao and collaborators show that miR-155 regulates T follicular helper cell development and function by suppressing the E3 ubiquitin ligase Peli1.
MicroRNA (miRNA) deficiency impairs the generation of T follicular helper (Tfh) cells, but the con
MicroRNA (miRNA) deficiency impairs the generation of T follicular helper (Tfh) cells, but the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa5ed3a272de3dc5bb9fdbe6d6cbcd4
http://hdl.handle.net/10486/685850
http://hdl.handle.net/10486/685850
Autor:
Ronald M. Evans, Annette R. Atkins, Ye Zheng, Michael Downes, Weiwei Fan, Christopher Liddle, Ruth T. Yu, Nanhai He, Brian Henriquez
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Regulatory T cells (Tregs) play a critical role in maintaining immune tolerance to self-antigens and in suppressing excessive immune responses that may cause collateral damage to the host. Unlike other CD4+ T cells, Tregs have a distinct