Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chao Xu"'
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Objective Poly (ADP-ribose) polymerase 1 (PARP1), as a key enzyme in the base excision repair pathway, plays a crucial role in tumorigenesis and progression. This study aimed to assess whether polymorphisms of PARP1 gene could be used as predictive b
Autor:
Chinthalapally V. Rao, Chao Xu, Yuting Zhang, Hiroshi Yamada, Adam S. Asch, Mudassir Farooqui
Publikováno v:
Cancers, Vol 13, Iss 2586, p 2586 (2021)
Cancers
Volume 13
Issue 11
Cancers
Volume 13
Issue 11
Chromosome Instability (CIN) in tumors affects carcinogenesis, drug resistance, and recurrence/prognosis. Thus, it has a high impact on outcomes in clinic. However, how CIN occurs in human tumors remains elusive. Although cells with CIN (i.e., pre/ea
Publikováno v:
Journal of Medical Virology
Coronaviruses are common human viruses and include the severe acute respiratory syndrome coronavirus (SARS-CoV), the middle east respiratory syndrome coronavirus and the SARS-CoV-2. Coronaviruses mainly bind to transmembrane receptor proteins on the
Autor:
Mengzhu Li, Xiaoming Zhou, Wenbin Chen, Jiajun Zhao, Lifang Zhao, Chao Xu, Xiaohan Zhang, Yongfeng Song, Shanshan Shao, Meng Zhao, Li Fang, Ling Gao, Rui Yang
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 316:E510-E518
Recent studies revealed the emerging role of excess uptake of lipids in the development of hypothyroidism. However, the underlying mechanism is largely unknown. We investigated the effect of high-fat diet (HFD) on thyroid function and the role of end
Autor:
Wei Guo, Xi Zhang, Lihua Qing, Linghua Meng, Jia-li Liu, Yi-chao Xu, Xue-ling Liu, Jian Ding, Yu-xiang Wang
Publikováno v:
International Journal of Cancer. 145:817-829
The hotspot mutation H1047R in the oncogenic PIK3CA gene is frequently detected in breast cancer and enhances the enzymatic activity of PI3K to activate AKT/mTOR signaling cascade. Aberrant elevated PI3K activation has been reported to promote the tu
Autor:
Jian Fang, Kang Ding, Hui Zhang, Wei Lu, Meng-Ling Cai, Yi-Jiang Ding, Xu Yang, Zhang Sumin, Shi-Cai Huang, Meng Li, Yang Ding, Yan Song, Da-Chao Xu, Yuan Fang, Yan-Yan Tan
Publikováno v:
Journal of Cellular Biochemistry. 120:5687-5694
In this article, we aim to examine the novel effects of β-sitosterol on murine experimental colitis. β-Sitosterol significantly reduces the weight loss, colon length, and alleviated microscopic appearances of colitis induced by dextran sulfate sodi
Autor:
Yu Gao, Shengwei Zheng, Yunfeng Lv, Hongran Li, Peirong Wang, Jinchun Dong, Wen Bao, Peng Hu, Chao Xu, Juanjuan An, Jingyun He, Gang Deng
Publikováno v:
Bioanalysis
Coronavirus disease-2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread globally since its first report and become a worldwide pandemic. In response to the outbreak of COVID-19, Center for Med
Publikováno v:
BMC Medical Genetics
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-9 (2020)
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-9 (2020)
Background Nuclear genome or family mitochondrial screening system has become the hot focus of studies into essential hypertension. The role of mitochondrial DNA (mtDNA) in sporadic Chinese patients with hypertension has not been fully understood. Th
Autor:
Yiping Cheng, Xiaoming Zhou, Xinli Zhou, Dongqing Jiang, Guimei Li, Guoxin Teng, Yan Sun, Yiming Ji, Chao Xu
Publikováno v:
Bioscience Reports
Androgen insensitivity syndrome (AIS; OMIM 300068) is the most frequent cause of 46, XY disorders of sex development (DSD). However, the correlation between genotype and phenotype has not been determined. We conducted a systematic analysis of the cli
Publikováno v:
Journal of Medical Virology
Since December 2019, a series of unexplained pneumonia cases have been reported in Wuhan, China. On 12 January 2020, the World Health Organization (WHO) temporarily named this new virus as the 2019 novel coronavirus (2019-nCoV). On 11 February 2020,