Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Mandy L. Ford"'
Autor:
Mandy L. Ford, Yini Sun, Jennifer M. Robertson, Aneesh K. Mehta, Marvi Tariq, Scott M. Krummey, Christina R. Hartigan, He Sun, Ching wen Chen
Publikováno v:
Am J Transplant
Belatacept confers increased patient and graft survival in renal transplant recipients relative to calcineurin inhibitors, but is associated with an increased rate of acute rejection. Recent immunophenotypic studies comparing pre-transplant T cell ph
Autor:
Mandy L. Ford, Zhe Liang, Craig M. Coopersmith, Ming Xue, Kristen N. Morrow, Yini Sun, He Sun, Ching-Wen Chen, Jianfeng Xie, Jerome C. Anyalebechi
Publikováno v:
The Journal of Immunology. 205:3358-3371
Immune dysregulation during sepsis is mediated by an imbalance of T cell costimulatory and coinhibitory signaling. CD28 is downregulated during sepsis and is significantly altered on memory versus naive T cells. Thus, to study the role of CD28 during
Autor:
Danya Liu, Mandy L. Ford
Publikováno v:
Am J Transplant
Antagonism of the CD154/CD40 pathway is a highly effective means of inducing long-term graft survival in pre-clinical models. Using a fully allogeneic murine transplant model, we found that CD154 blockade was more effective in prolonging graft surviv
Publikováno v:
Am J Transplant
CTLA-4Ig (belatacept) blocks the CD80/CD86 ligands for both CD28 and CTLA-4; thus, in addition to the intended effect of blocking CD28-mediated costimulation, belatacept also has the unintended effect of blocking CTLA-4-mediated coinhibition. Recentl
Autor:
Shunsuke Otani, Rebecca L. Crepeau, Jianfeng Xie, Mandy L. Ford, Ching-Wen Chen, Wenxiao Zhang, Craig M. Coopersmith
Publikováno v:
Journal of Leukocyte Biology. 105:565-575
Epstein–Barr virus (EBV) reactivation commonly occurs following sepsis, but the mechanisms underlying this are unknown. We utilized a murine EBV homolog (gHV) and the cecal ligation and puncture model of polymicrobial sepsis to study the impact of
Publikováno v:
Transplant Immunology. 50:34-42
Models of infection have shaped our understanding of programmed memory T cell differentiation, yet whether these models apply to memory programming in the context of transplantation has yet to be defined. Previous work has identified differences in t
Autor:
Ronald G. Gill, Sandy Feng, Peter Nickerson, Garnett Kelsoe, Patricia Campbell, Michael Mengel, Roslyn B. Mannon, I. Esme Dijke, Anat R. Tambur, Elaine F. Reed, Chris Wiebe, Vasilis Kosmoliaptsis, Mandy L. Ford, Howard M. Gebel, Anita S. Chong, Nicole Valenzuela, Harold C. Sullivan
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, vol 20, iss 10
American Journal of Transplantation
American Journal of Transplantation
The purpose of the STAR 2019 Working Group was to build on findings from the initial STAR report to further clarify the expectations, limitations, perceptions, and utility of alloimmune assays that are currently in use or in development for risk asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870ca5cc75c7e6b7fa12e80c5980b142
https://escholarship.org/uc/item/4ft4n42d
https://escholarship.org/uc/item/4ft4n42d
Autor:
Glenn Michael La Muraglia, Idelberto R. Badell, Emma S. Crichton, Maylene E. Wagener, Susan Zeng, Mandy L. Ford
Publikováno v:
Am J Transplant
Anti-donor antibodies cause immunologic injury in transplantation. CD28 blockade with CTLA-4-Ig has the ability to reduce the incidence of these donor-specific antibodies (DSA), but its mechanism is suboptimal for the inhibition of alloimmunity in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f3dc80ed22866d214e692620daa73b
https://europepmc.org/articles/PMC7665991/
https://europepmc.org/articles/PMC7665991/
Autor:
Paolo Cravedi, Clara R. Farley, Mark S. Cragg, Anna B. Morris, David F. Pinelli, Christopher D. Scharer, Layne E. Adams, Miguel Fribourg, Jeremy M. Boss, Mandy L. Ford, Peter S. Heeger
Effector CD8+ T cells are important mediators of adaptive immunity, and receptor-ligand interactions that regulate their survival may have therapeutic potential. Here, we identified a subset of effector CD8+ T cells that expressed the inhibitory frag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f883b2a890042dd5b19c0f8850e2c7ba
https://eprints.soton.ac.uk/437211/
https://eprints.soton.ac.uk/437211/
Autor:
Anna B. Morris, Mandy L. Ford
Publikováno v:
Curr Opin Organ Transplant
Purpose of review Studies on adaptive cells have largely focused on features that are specific to adaptive immunity. However, adaptive cells utilize innate cell features to modulate their responses, and this area of T and B-cell biology is understudi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bb1a89968e6e732cfd7a4e933c3d07
https://europepmc.org/articles/PMC7175961/
https://europepmc.org/articles/PMC7175961/