Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Daniel D. De Carvalho"'
Autor:
Bo Zhang, Yasheng Zhu, Xiaojie Bian, Mingyao Liu, Daniel D. De Carvalho, Chao Wang, Zhengfang Yi, Yu-Tian Xiao, Song Wu, Housheng Hansen He, Fraser Soares, Paul C. Boutros, Theodorus H. van der Kwast, Zhou Jiang, Ke-Qin Dong, Javier Mariscal, Jianhua Wang, Helen Loo Yau, Alejandro Berlin, Guanghui Zhu, Qinghua Guo, Weidong Chen, Fubo Wang, Shancheng Ren, Yongwei Yu, Yue Yang, Dolores Di Vizio, Na Zhang, Michael Fraser, Fei Liu, Dai Chen, Yin Liu, Sujun Chen
Publikováno v:
Nature cell biology. 23(1)
Prostate cancer shows remarkable clinical heterogeneity, which manifests in spatial and clonal genomic diversity. By contrast, the transcriptomic heterogeneity of prostate tumours is poorly understood. Here we have profiled the transcriptomes of 36,4
Autor:
Craig Horbinski, Farshad Nassiri, Daniel D. De Carvalho, Kenneth Aldape, Vikas Patil, Gelareh Zadeh, Ankur Chakravarthy, Shu Yi Shen, Mathew Voisin, Shengrui Feng, Romina Nejad, Jeffrey Zuccato
Publikováno v:
Nat Med
Nat Rev Clin Oncol
Nat Rev Clin Oncol
Definitive diagnosis of intracranial tumors relies on tissue specimens obtained by invasive surgery. Noninvasive diagnostic approaches provide an opportunity to avoid surgery and mitigate unnecessary risk to patients. In the present study, we show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbee80f0c82655ec4a144b807866701b
https://europepmc.org/articles/PMC8500275/
https://europepmc.org/articles/PMC8500275/
Autor:
Benjamin Ellezam, Paul Guilhamon, Peter W. Lewis, Nicolas De Jay, Nada Jabado, Josie Ursini-Siegel, Sameer Agnihotri, Mathieu Lupien, Peter B. Dirks, Paul Lasko, Ashot S. Harutyunyan, Stephen C. Mack, Damien Faury, Robert F. Koncar, Carol C.L. Chen, Paolo Salomoni, Dylan M. Marchione, Shriya Deshmukh, Daniel D. De Carvalho, Leonie G. Mikael, Alexander G. Weil, Claudia L. Kleinman, Melissa K. McConechy, Brian Krug, Kelsey C. Bertrand, Benjamin A. Garcia, Sima Khazaei, Cheryl H. Arrowsmith
Publikováno v:
Cancer Cell
Cancer cell 35(5), 782-797.e8 (2019). doi:10.1016/j.ccell.2019.04.004
Cancer cell 35(5), 782-797.e8 (2019). doi:10.1016/j.ccell.2019.04.004
High-grade gliomas (HGG) defined by histone 3 K27M driver mutations exhibit global loss of H3K27 trimethylation and reciprocal gain of H3K27 acetylation, respectively shaping repressive and active chromatin landscapes. We generated tumor-derived isog
Autor:
Theresa K. Kelly, Gangning Liang, Jueng Soo You, Shikhar Sharma, Xiaojing Yang, Sheng-Fang Su, Phillippa C. Taberlay, Peter A. Jones, Daniel D. De Carvalho
Publikováno v:
Cancer Cell. 21(5):655-667
SummaryCancer cells typically exhibit aberrant DNA methylation patterns that can drive malignant transformation. Whether cancer cells are dependent on these abnormal epigenetic modifications remains elusive. We used experimental and bioinformatic app