Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Margery A. Connelly"'
Autor:
Robin P. F. Dullaart, Margery A. Connelly, Stephan J. L. Bakker, B. D. Westenbrink, Dion Groothof, Adrian Post, Jose L. Flores-Guerrero, Eke G. Gruppen, Erwin Garcia, Eline H. van den Berg
Publikováno v:
European Journal of Clinical Investigation, 51(12):13627, 1-12. Wiley
Background Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent, paralleling the obesity epidemic. Ketone bodies are produced in the liver, but it is currently uncertain whether circulating ketone bodies are increased in the context of
Autor:
Eke G. Gruppen, Trynke van der Boom, Joop D. Lefrandt, Thera P. Links, Robin P. F. Dullaart, Margery A. Connelly
Publikováno v:
Scandinavian Journal of Clinical & Laboratory Investigation, 80(7), 562-566. Taylor & Francis Ltd
Branched chain amino acids (BCAA) are implicated in the pathogenesis of cardiometabolic diseases conceivably by affecting insulin resistance and mitochondrial dysfunction. Circulating BCAA levels may predict (subclinical) atherosclerosis, diabetes an
Autor:
B. D. Westenbrink, James D. Otvos, Robin P. F. Dullaart, Margery A. Connelly, Erwin Garcia, Jose L. Flores-Guerrero, Irina Shalaurova, Gerjan Navis, Stephan J. L. Bakker, Dion Groothof, Rudolf A. de Boer
Publikováno v:
European Journal of Clinical Investigation, 51(5):13468. Wiley
European Journal of Clinical Investigation
European Journal of Clinical Investigation
Background In the failing heart, energy metabolism is shifted towards increased ketone body oxidation. Nevertheless, the association of beta-hydroxybutyrate (beta-OHB) with development of heart failure (HF) remains unclear. We investigated the associ
Autor:
Margery A. Connelly, Elias J. Jeyarajah, Franklin C. Warf, James D. Otvos, David N. Oskardmay, Dennis W. Bennett, Justyna Wolak-Dinsmore, Maureen Sampson, Erwin Garcia, Steven P. Matyus, Irina Shalaurova, Alan T. Remaley, Randolph M. Young
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-11 (2020)
Lipids in Health and Disease
Lipids in Health and Disease
Background Standard lipid panel assays employing chemical/enzymatic methods measure total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C), from which are calculated estimates of low-density lipoprotein cholester
Autor:
Sara Sokooti, Robin P. F. Dullaart, Margery A. Connelly, Stephan J. L. Bakker, Jose L. Flores-Guerrero, Hiddo J.L. Heerspink, Lyanne M. Kieneker
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
The Journal of Clinical Endocrinology & Metabolism
Journal of Clinical Endocrinology and Metabolism, 106(6), 1761-1772. ENDOCRINE SOC
The Journal of Clinical Endocrinology & Metabolism
Journal of Clinical Endocrinology and Metabolism, 106(6), 1761-1772. ENDOCRINE SOC
ContextHigh-density lipoproteins (HDL) may be protective against type 2 diabetes (T2D) development, but HDL particles vary in size and function, which could lead to differential associations with incident T2D. A newly developed nuclear magnetic reson
Autor:
Steven P. Matyus, Russell P Grant, Stephan J. L. Bakker, James D. Otvos, Ray Gegen, Robin P. F. Dullaart, Margery A. Connelly, Eke G. Gruppen, Justyna Wolak-Dinsmore, Irina Shalaurova
Publikováno v:
Clinical biochemistry, 54, 92-99. PERGAMON-ELSEVIER SCIENCE LTD
Objectives Plasma branched-chain amino acid (BCAA) levels, measured on nuclear magnetic resonance (NMR) metabolomics research platforms or by mass spectrometry, have been shown to be associated with type 2 diabetes mellitus (T2DM) and cardiovascular
Autor:
Justyna Wolak-Dinsmore, Margery A. Connelly, Stanley L. Hazen, Dennis W. Bennett, James D. Otvos, Elias J. Jeyarajah, Erwin Garcia, Xinmin S. Li, Zeneng Wang
Publikováno v:
Clinical Biochemistry. 50:947-955
Background and objectives Trimethylamine- N -oxide (TMAO) produced by gut microbiota metabolism of dietary choline and carnitine has been shown to be associated with increased risk of cardiovascular disease (CVD) and to provide incremental clinical p
Autor:
Margery A. Connelly, Joseph B. Muhlestein, Heidi T May, Jeffrey L. Anderson, Deborah A. Winegar, James D. Otvos, Jeffrey Rollo
Publikováno v:
Clinical Biochemistry. 49:1122-1126
HDL-C is recognized to be inversely associated with cardiovascular (CV) risk. However, attenuation of the association of HDL-C with CV risk may occur after adjustment for other lipoprotein parameters and in various disease states, especially in the s
Publikováno v:
Clinica Chimica Acta. 459:177-186
The physiological function initially attributed to the oligosaccharide moieties or glycans on inflammatory glycoproteins was to improve protein stability. However, it is now clear that glycans play a prominent role in glycoprotein structure and funct
Autor:
Wim J. Sluiter, Stephan J. L. Bakker, Eke G. Gruppen, Robin P. F. Dullaart, Margery A. Connelly
Publikováno v:
Clinica chimica acta, 488, 7-12. ELSEVIER SCIENCE BV
Objective: Elevated circulating levels of pro-inflammatory biomarkers are associated with adverse health effects, but the extent to which enhanced low-grade inflammation influences remaining life expectancy (LE) is uncertain. GlycA is a novel pro-inf