Zobrazeno 91 - 100
of 32 177
pro vyhledávání: ''
Autor:
Masakatsu Hishizawa, Seishi Ogawa, Toshio Kitawaki, Yasuhito Nannya, Takuya Shimizu, Takero Shindo, Mizuki Watanabe, Kouhei Yamashita, Akifumi Takaori-Kondo, Tadakazu Kondo
Publikováno v:
Journal of Cellular and Molecular Medicine
Acute basophilic leukaemia (ABL) is a rare subtype of acute myeloid leukaemia (AML); therefore, few data are available about its biology. Herein, we analysed two ABL patients using flow cytometry and next-generation sequencing (NGS). Two cell populat
Autor:
Simona Sica, Maria Bianchi, Elisabetta Metafuni, Patrizia Chiusolo, Caterina Giovanna Valentini, Andrea Bacigalupo, Nicoletta Orlando, Luciana Teofili, Sabrina Giammarco
Publikováno v:
Cytotherapy
Background: The coronavirus disease 2019 (COVID-19) pandemic has deeply modified the complex logistical process underlying allogeneic hematopoietic stem cell transplant practices. Aim: In light of these changes, the authors compared data relative to
Autor:
Weijun Liu, Weiyang Cai, Ying-Li Wu, Wenfu Tan, Jun Yang, Yu Zou, Yuan Liu, Qingqing Ding, Wenjing Huang, Yu Zhang, Juan Wang, Jing Gao, Hu Zhou, Zhang Yanjie, Pei hao Yin, Yanyan Qiu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Both bench and bedside investigations have challenged the supportive role of Hedgehog (Hh) activity in the progression of colorectal cancers, thus raising a critical need to further deeply determine the contribution of Hh to the growth of colorectal
Autor:
David R. Martinez, Tomohiro Kawano, Ursula Rauch, Joseph S. Palumbo, Leah Rosenfeldt, Vanthana Bharathi, Silvio Antoniak, Clare M. Schmedes, Alice Weithauser, Grant J. Egnatz, Yohei Hisada, Michael Bode, Nigel Mackman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Protease-activated receptor 1 (PAR1) is widely expressed in humans and mice, and is activated by a variety of proteases, including thrombin. Recently, we showed that PAR1 contributes to the innate immune response to viral infection. Mice with a globa
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-8 (2021)
Cell Death & Disease
Cell Death & Disease
Receptor interaction protein kinase 1 (RIPK1) plays a diverse role in tumor necrosis factor α (TNFα) signalings. The ubiquitination of RIPK1 is essential for NF-κB activation, whereas its kinase activity promotes apoptosis and necroptosis. However
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Chemotherapy remains the primary treatment of advanced solid cancer, including lung cancer. However, as first-line treatment, cisplatin-based therapy is restricted by the frequent development of drug resistance. Increasing data showed that the progra
Autor:
Wei Liu, Lijian Xie, Cuilan Hou, Tingting Xiao, Xiaomin Sun, Meng Xu, Yongwei Zhang, Junmin Zheng, Yun Li
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
Congenital heart defects, one of the most common birth defects, affect approximately 1% of live birth globally and remain the leading cause of infant mortality in developed countries. Utilizing the pathogenicity score and inheritance mode from whole
Autor:
James E. Huettner, Kristen L. Kroll, Kesavan Meganathan, Fumihiko Urano, Susan E. Maloney, Ramachandran Prakasam, Dustin Baldridge, Azad Bonni, John N. Constantino, Bo Zhang, Paul Gontarz, Tychele N. Turner
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-26 (2021)
BMC Biology
BMC Biology
Background Copy number variants (CNVs) linked to genes involved in nervous system development or function are often associated with neuropsychiatric disease. While CNVs involving deletions generally cause severe and highly penetrant patient phenotype
Autor:
W. G. Li, Matthew D. Ringel, Sandya Liyanarachchi, Pearlly S. Yan, Albert de la Chapelle, Daniel F. Comiskey, Huiling He, Ralf Bundschuh, Altan M. Turkoglu, Pamela Brock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. The molecular characteristics of histologically normal appearing tissue adjacent to the tumor (NAT) from PTC patients are not well characterized. The aim of this study was t
Autor:
Zheng-Yang Wu, Zhanguo Sun, Xinwei Han, Peng Li Zhou, Miao Xu, Wenguang Zhang, Qinhui Zhang, Jianzhuang Ren
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Growing evidence has indicated that circular RNAs (circRNAs) play a pivotal role as functional RNAs in diverse cancers. However, most circRNAs involved in esophageal squamous cell carcinoma (ESCC) remain undefined, and the underlying molecular mechan