Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Marc Valentine"'
Autor:
Heather L. Mulder, Peter Vogel, Steven Henikoff, Marcin Kamiński, Richard K. Wilson, Jinghui Zhang, Anang A. Shelat, James R. Downing, Marc Valentine, Yanling Liu, Xin Zhou, Yiping Fan, Armita Bahrami, Arlene Naranjo, Collin Van Ryn, Rani E. George, Sara M. Federico, Beisi Xu, Jongrye Jeon, Seungjae Lee, Xiang Chen, Elizabeth Stewart, John Easton, Donald Yergeau, Shondra M. Pruett-Miller, Jay F. Sarthy, Michael P. Meers, Maged Zeineldin, Michael A. Dyer, Lyra Griffiths, Michael R. Clay, Jackie L. Norrie, Elaine R. Mardis, Rosa Nguyen, Alberto S. Pappo, Michael D. Hogarty, Jianrong Wu
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Aggressive cancers often have activating mutations in growth-controlling oncogenes and inactivating mutations in tumor-suppressor genes. In neuroblastoma, amplification of the MYCN oncogene and inactivation of the ATRX tumor-suppressor gene correlate
Autor:
Marc Valentine, Patrick A. Zweidler-McKay, Sa A. Wang, Kathryn G. Roberts, Nitin Jain, Charles G. Mullighan, Marina Konopleva, Xinyan Lu, Maitrayee Goswami, Jeffrey L. Jorgensen, Sergej Konoplev, Carlos E. Bueso-Ramos, Juan Ouyang
Publikováno v:
American Journal of Clinical Pathology. 147:357-363
Objectives Cytokine receptor-like factor 2 ( CRLF2 ) rearrangement is found in approximately 50% of pediatric Ph-like B-cell acute lymphoblastic leukemia (B-ALL), and around 50% of CRLF2 + cases harbor JAK mutations. We analyzed CRLF2 expression and
Autor:
Diane Flasch, Jinghui Zhang, Yanling Liu, Michael Rusch, Suzanne J. Baker, Robin Paul, Jaimin Patel, Chunliang Li, Ying Shao, Edgar Sioson, Xiaotu Ma, Yu Liu, Liqing Tian, John Easton, Marc Valentine, Samuel W. Brady, Scott Newman, Jian Wang, Xin Zhou, Michael N. Edmonson
Publikováno v:
Cancer Cell
GenomePaint (https://genomepaint.stjude.cloud/) is an interactive visualization platform for whole-genome, whole-exome, transcriptome, and epigenomic data of tumor samples. Its design captures the inter-relatedness between DNA variations and RNA expr
Autor:
Stephen P. Hunger, Elizabeth A. Raetz, Julie M. Gastier-Foster, Cheryl L. Willman, Mignon L. Loh, Yu Liu, Brent L. Wood, William L. Carroll, Heather Jenkins, Andrew J. Carroll, Eileen Stonerock, Jonathan V. Nguyen, Michael J. Burke, Yunfeng Dai, Zhaohui Gu, Karen R. Rabin, John Easton, I-Ming Chen, Thai Hoa Tran, Anne L. Angiolillo, Amy Smith, Kathryn G. Roberts, Meenakshi Devidas, Debbie Payne-Turner, Michael J. Borowitz, Marc Valentine, Charles G. Mullighan, Patrick A. Zweidler-McKay, Yongjin Li, Ying Shao, Nyla A. Heerema, Wanda L. Salzer, Jinghui Zhang, Richard C. Harvey, Shalini C. Reshmi
Publikováno v:
Blood. 129(25)
Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk subtype characterized by genomic alterations that activate cytokine receptor and kinase signaling. We examined the frequency and spectrum of targetable genetic l