Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Chao Xu"'
Autor:
Joshua M. Corbin, Jonathan D. Wren, Constantin Georgescu, Chao Xu, Adam S. Asch, Maria J. Ruiz-Echevarria
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss, Pp 337-351 (2021)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Resistance to anti-androgen therapy in prostate cancer (PCa) is often driven by genetic and epigenetic aberrations in the androgen receptor (AR) and coregulators that maintain androgen signaling activity. We show that specific small RNAs downregulate
Publikováno v:
Biochemical and Biophysical Research Communications. 557:236-239
C-degrons play critical roles in targeting the receptor proteins of Cullin-RING E3 ligase complexes to initiate protein degradation. FEM1 proteins, including FEM1A, FEM1B, and FEM1C, act as the receptors to specifically recognize Arg/C-degrons to ena
Autor:
Boyuan Zheng, Feihong Yang, Qiuhuan Yuan, Youshun Xu, Baoshan Liu, Li Xue, Yu Zhao, Jiali Wang, Shuai Dai, Rui Zhang, Shengchuan Cao, Tonghui Xu, Bai-Chao Xu, Feng Xu, Shu-jian Wei, Mengyang Xue, Yi Sun, Wenjun Wang, Yuguo Chen, Sumei Cui, Zheng Wang
Publikováno v:
Biochemical and Biophysical Research Communications. 533:1427-1434
Sympathetic stimulated-cardiac fibrosis imposes great significance on both disease progression and survival in the pathogenesis of many cardiovascular diseases. However, there are few effective therapies targeting it clinically. The cardioprotective
Publikováno v:
Innate Immunity
Innate Immunity, Vol 26 (2020)
Innate Immunity, Vol 26 (2020)
Sepsis is the major cause of mortality in the intensive care unit. The aim of this study was to identify the key prognostic biomarkers of abnormal expression and immune infiltration in sepsis. In this study, a total of 36 differentially expressed gen
Autor:
Jinrong Min, Deqiang Ding, Chen Chen, Jian Hu, Jiali Liu, Kunzhe Dong, Chao Xu, Chao Wei, Alexander Stanton
Publikováno v:
Nucleic Acids Research
LOTUS domains are helix-turn-helix protein folds identified in essential germline proteins and are conserved in prokaryotes and eukaryotes. Despite originally predicted as an RNA binding domain, its molecular binding activity towards RNA and protein
Autor:
Peng Hu, Chao Xu, Juanjuan An, Jinchun Dong, Shengwei Zheng, Rongzhi Liu, Jingyun He, Congyin Han, Yunfeng Lv, Yu Gao, Gang Deng, Li Fang, Ran Li, Lei Sun
Publikováno v:
Journal of Medical Virology
The detection data of IgM and IgG antibodies in 169 patients with coronavirus disease (COVID‐19) were analyzed to evaluate differences in clinical performance between the colloidal gold method and chemiluminescence method. In this study, chemilumin
Publikováno v:
Infection and Drug Resistance. 13:2601-2607
Background Candida species are commonly detected as colonizers of the oral cavity; candidiasis or candidemia can develop in patients who are immunocompromised. Use of topical or inhaled glucocorticoids can alter the spectrum of Candida species and ca
Publikováno v:
Cancer Chemotherapy and Pharmacology. 85:1049-1062
Malnutrition is a common clinical symptom in cancer patients after chemotherapy, which is characterized by muscle wasting and metabolic dysregulation. The regulation of muscle metabolism by gut microbiota has been studied recently. However, there is
Autor:
Ji-feng Jiang, Bin Lin, Xiao-pei Xu, Lu-lu Gao, Shi-ya Li, Hua-fu Luo, Chao Xu, Ju-jiang Mao, Nan Lu, Jian Lv, Zhu-jing Shen, Kai Li
Publikováno v:
Journal of Zhejiang University. Science. B
In December 2019, coronavirus disease 2019 (COVID-19), a new de novo infectious disease, was first identified in Wuhan, China and quickly spread across China and around the world. The etiology was a novel betacoronavirus, the severe acute respiratory
Autor:
Hongming Ji, Yan Sun, Guijun Jia, Dengpeng Ren, Lina Wang, Jing Wang, Rui Cheng, Chao Xu, Jin-Rui Ren, Yue Tu, Chunhong Wang, Jiuhong Ma
Publikováno v:
Journal of Cellular and Molecular Medicine
Glioblastoma (GBM) is one of the most common aggressive cancers of the central nervous system in adults with a high mortality rate. Bortezomib is a boronic acid–based potent proteasome inhibitor that has been actively studied for its anti‐tumour