Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zewen K. Tuong"'
Autor:
Raymond J. Steptoe, Andrew W. Lewandowski, James W. Wells, H. Peter Soyer, Fiona Simpson, Graham R. Leggatt, Ian H. Frazer, Duncan Lambie, Miko Yamada, Zewen K. Tuong, Richard Lewandowski, Jazmina L. G. Cruz, Jennifer A. Bridge
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Actinic Keratosis (AK), Intraepidermal Carcinoma (IEC), and Squamous Cell Carcinoma (SCC) are generally considered to be advancing stages of the same disease spectrum. However, while AK often regress spontaneously, and IEC often regress in response t
Autor:
Germain J. P. Fernando, Hwee-Ing Ng, Mark A. F. Kendall, Zewen K. Tuong, Stefano C. Meliga, Ian H. Frazer, Alexandra C. I. Depelsenaire
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-12 (2019)
NPJ Vaccines
NPJ Vaccines
Chemical adjuvants are typically used to improve immune responses induced by immunisation with protein antigens. Here we demonstrate an approach to enhance immune responses that does not require chemical adjuvants. We applied microprojection arrays t
Autor:
Zhen Zeng, James W. Wells, Ian H. Frazer, Margaret Veitch, Jazmina Gonzalez Cruz, Zewen K. Tuong, Gabrielle A. Kelly
Publikováno v:
Cancers, Vol 13, Iss 2131, p 2131 (2021)
Cancers
Volume 13
Issue 9
Cancers
Volume 13
Issue 9
Simple Summary Cutaneous squamous cell carcinoma (SCC) is prevalent in aged individuals and individuals with compromised or weakened immune systems, indicating a close association between immune function and SCC control. The aim of our study was to u
Autor:
Tomas Castro-Dopico, Chenzhi Jing, Simon Clare, Thomas W. Dennison, Katherine Harcourt, John R. Ferdinand, Menna R. Clatworthy, Arthur Kaser, Laurence S C Lok, Zaeem Cader, Aaron M. Fleming, Benjamin J. Stewart, Anaïs Portet, Rebeccah J. Mathews, Zewen K. Tuong
Publikováno v:
Cell Reports
Summary Macrophages play a central role in intestinal immunity, but inappropriate macrophage activation is associated with inflammatory bowel disease (IBD). Here, we identify granulocyte-macrophage colony stimulating factor (GM-CSF) as a critical reg
HPV16E7-Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3+ T-Cell Migration to Skin
Autor:
Zewen K. Tuong, Graham R. Leggatt, Ian H. Frazer, Stephen Œr. Mattarollo, Paula Kuo, Siok Min Teoh
Publikováno v:
Journal of Investigative Dermatology. 138:1348-1359
Chemokines regulate tissue immunity by recruiting specific subsets of immune cells. Mice expressing the E7 protein of human papilloma virus 16 as a transgene from a keratin 14 promoter (K14.E7) show increased epidermal and dermal lymphocytic infiltra
Publikováno v:
EBioMedicine
EBioMedicine, Vol 9, Iss C, Pp 314-323 (2016)
EBioMedicine, Vol 9, Iss C, Pp 314-323 (2016)
A validated animal model would assist with research on the immunological consequences of the chronic expression of stress keratins KRT6, KRT16, and KRT17, as observed in human pre-malignant hyperproliferative epithelium. Here we examine keratin gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb5fd68be56ac44c9228619ca11af53
Autor:
Ian H. Frazer, Zewen K. Tuong, Christopher F. L. Perry, Rohit Sinha, Caroline Cooper, Andrew P. Zammit
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0205406 (2018)
PLoS ONE, Vol 13, Iss 10, p e0205406 (2018)
Oral cavity Squamous Cell Carcinoma (OCSCC) is a common form of head and neck cancer throughout the developed and developing world. However, the etiology of OCSCC is still unclear. Here, we explored the extent to which tobacco use, Human Papillomavir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adebc81a18294af7c859d564fba4afa
Publikováno v:
Papillomavirus Research, Vol 4, Iss, Pp 58-65 (2017)
Papillomavirus Research
Papillomavirus Research
High-risk human papillomaviruses (HR-HPV) infect basal keratinocytes, where in some individuals they evade host immune responses and persist. Persistent HR-HPV infection of the cervix causes precancerous neoplasia that can eventuate in cervical cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef1aa6a3bd154518d6cca6d3fc72769
Autor:
Zewen K. Tuong, Menna R. Clatworthy
Publikováno v:
Nature Reviews Nephrology. 16:570-571
The generation of local immune responses in organs requires a coordinated effort, not just from immune cells, but also from ‘structural’ cells such as epithelial cells, endothelial cells and fibroblasts. New insights gained from profiling these c
Autor:
Hui Yi Chew, Margaret Veitch, Jazmina L. G. Cruz, Xuzhi He, Shannon R. Joseph, James W. Wells, Nicola Pett, Gabrielle A. Kelly, Zewen K. Tuong, Fiona Simpson, Satomi Okano
Publikováno v:
Oncotarget
The Epidermal Growth Factor Receptor (EGFR) is selectively expressed on the surface of numerous tumours, such as non-small cell lung, ovarian, colorectal and head and neck carcinomas. EGFR has therefore become a target for cancer therapy. Cetuximab i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676104c24576f2733ac56ecce95694d2