Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Xiawei Wei"'
Targeting CXCR2 inhibits the progression of lung cancer and promotes therapeutic effect of cisplatin
Autor:
Yuan Cheng, Xuejiao Han, Qingfang Li, Fei Mo, Xiawei Wei, Yuquan Wei, Houhui Shi, Siyuan Chen
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Molecular Cancer
Molecular Cancer
Background Drug-resistance and severe side effects of chemotherapeutic agents result in unsatisfied survival of patients with lung cancer. CXCLs/CXCR2 axis plays an important role in progression of cancer including lung cancer. However, the specific
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-26 (2021)
Molecular Biomedicine
Molecular Biomedicine
Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). COVID-19 can spread to the entire body and cause multiple organ failure. It is a daunting challenge to control
Autor:
Chunju Fang, Wei Wang, Xiawei Wei, Ke Men, Li Liu, Fei Mo, Hanshuo Yang, Jing Du, Feifei Na, Min Luo
Publikováno v:
Cellular and Molecular Immunology
Exposure to ionizing radiation, a physical treatment that inactivates live tumor cells, has been extensively applied to enhance the antitumor responses induced by cancer cell vaccines in both animal research and human clinical trials. However, the me
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 1, Pp 199-223 (2020)
Clinical and Translational Medicine
Clinical and Translational Medicine
Surgical resection remains the mainstay treatment for solid cancers, especially for localized disease. However, the postoperative immunosuppression provides a window for cancer cell proliferation and awakening dormant cancer cells, leading to rapid r
Autor:
Xuelei Ma, Zhenfei Bi, Xiangxian Zhang, Xiawei Wei, Xiao Liang, Jingyun Yang, Yu Liu, Wen Nie, Zhiyao He, Yuquan Wei, Lu Sun, Yan Tie, Bin Shao, Dan Xie, Fei Mo, Xia Yuan
Publikováno v:
Theranostics
Rationale: The adverse health effects of nano-particulate pollutants have attracted much attention in recent years. Carbon nanomaterials are recognized as risk factors for prolonged inflammatory responses and diffuse alveolar injury. Previous researc
Publikováno v:
Cancer Letters. 469:367-379
Low pH and lactate accumulation are characteristic features of the tumour microenvironment. With our study finding that high concentrations of lactic acid can inhibit tumour growth, it is conceivable that the administration of lactic acid could promo
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 4, Iss 1, Pp 1-39 (2019)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Epigenetic alternations concern heritable yet reversible changes in histone or DNA modifications that regulate gene activity beyond the underlying sequence. Epigenetic dysregulation is often linked to human disease, notably cancer. With the developme
Publikováno v:
Cancer Medicine, Vol 9, Iss 2, Pp 496-506 (2020)
Purpose Our study assessed the ability 18F‐fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) radiomics to differentiate breast carcinoma from breast lymphoma using machine‐learning approach. Methods Sixty‐five
Publikováno v:
Cellular and Molecular Immunology
Macrophages are crucial members of the innate immune response and important regulators. The differentiation and activation of macrophages require the timely regulation of gene expression, which depends on the interaction of a variety of factors, incl
Autor:
Xiawei Wei, Xing Zhang, Wenxian Yang, Ting Wang, Haohao Dong, Zhibo Zhang, Wen Qiao, Xiaodi Tang, Zhengyu Zhang, Yang Niu, Xiaofeng Zhu, Changjiang Dong, Qinghua Luo, Shenghai Chang, Changbin Zhang, Caihuang Xu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Lipopolysaccharides (LPS) of Gram-negative bacteria are critical for the defence against cytotoxic substances and must be transported from the inner membrane (IM) to the outer membrane (OM) through a bridge formed by seven membrane proteins (LptBFGCA