Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Xiang-sheng Zhang"'
Autor:
Sen Gao, Xiang-Sheng Zhang, Cang Liu, Tao Tao, Chun-Hua Hang, Zong Zhuang, Yi-Ting Guo, Wen Li, Yan Zhou, Yue Lu, Wei Li, Wei-Han Wang
Publikováno v:
British Journal of Pharmacology. 178:3648-3666
BACKGROUND AND PURPOSE Dioscin has multiple biological activities and is beneficial for cardiovascular and cerebral vascular diseases. Here, we investigated the protective effects of dioscin against subarachnoid haemorrhage and the molecular mechanis
Autor:
Chun-Hua Hang, Xiang-Sheng Zhang, Yue Lu, Da-Yong Xia, Cang Liu, Tao Tao, Wei Li, Lei Peng, Wen Li, Zong Zhuang, Sen Gao, Wei-Han Wang
Publikováno v:
British Journal of Pharmacology. 178:1114-1132
Background and purpose Oxidative stress and neuronal apoptosis play key roles in traumatic brain injury. We investigated the protective effects of astaxanthin against traumatic brain injury and its underlying mechanisms of action. Experimental approa
Autor:
Da-Yong Xia, Yue Lu, Chun-Hua Hang, Xiang-Sheng Zhang, Han Wang, Tao Tao, Xun-Zhi Liu, Guang-Jie Liu, Cang Liu, Wei Li
Publikováno v:
Molecular Neurobiology. 57:5286-5298
Oxidative stress is a key component of the pathological cascade in subarachnoid hemorrhage (SAH). Fucoxanthin (Fx) possesses a strong antioxidant property and has shown neuroprotective effects in acute brain injuries such as ischemic stroke and traum
Autor:
Lijun Hou, Jigang Chen, Shengyin Lv, Xiang-Sheng Zhang, Qi Wu, Jiang Shao, Yuan Zhou, Xiao-Ming Zhou, Yue Lu, Chengguang Huang, Xin Zhang
Publikováno v:
The FASEB Journal. 33:9588-9601
Platelet-derived growth factor receptor β (PDGFRβ) dynamically changes after brain injury, possibly mediating the neuroprotective role of soluble homodimers of the platelet-derived growth factor β subunit (PDGF-BB) that is secreted by microcircula
Autor:
Yong-Yue Gao, Zi-Huan Zhang, Yue Lu, Xiao-Ming Zhou, Xiang-Sheng Zhang, Wei Li, Chun-Hua Hang, Zhen-Nan Ye, Chun-Lei Chen, Ling-Yun Wu, Jing-Peng Liu
Publikováno v:
The FASEB Journal. 33:3051-3062
Recent studies suggest that peroxiredoxin1/2 (Prx1/2) may be involved in the pathophysiology of postischemic inflammatory responses in the brain. In this study, we assessed the distribution and function of Prx1/2 in mice after experimental subarachno
Autor:
Xiang-hua Zhang, Xiang-Sheng Zhang, Yi-Peng Dong, Da-Yong Xia, Cheng-Jun Wang, Jing Zhang, Lei Peng, Cang Liu
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology, Vol 11 (2020)
Excessive cerebral inflammation plays a key role in early brain injury (EBI) after subarachnoid hemorrhage (SAH). Berberine, an isoquinoline alkaloid isolated from Chinese herb Coptis chinensis, possesses anti-inflammatory, and neuroprotective effect
Autor:
Yong-Yue Gao, Haibin Dai, Yue Lu, Chun-Hua Hang, Zong Zhuang, Ling-Yun Wu, Xiang-Sheng Zhang, Tao Tao, Yan Zhou, Han Wang, Guang-Jie Liu, Wei Li
Publikováno v:
Molecular neurobiology. 58(5)
Excessive inflammation is a major cause contributing to early brain injury (EBI) and is associated with negative or catastrophic outcomes of subarachnoid hemorrhage (SAH). Resolvin D1 (RvD1) exerts strong anti-inflammatory and pro-resolving effects o
Autor:
Jing-Peng Liu, Guang-bin Xie, Xiang-Sheng Zhang, Meng-Liang Zhou, Ling-Yun Wu, Chen-Hui Zhou, Ji-Xin Shi, Chun-Hua Hang, Chun-xi Wang, Zhen-Nan Ye, Yong-Yue Gao, Zong Zhuang, Chao Tang
Publikováno v:
Behavioural Neurology, Vol 2018 (2018)
Behavioural Neurology
Behavioural Neurology
Inflammatory injury and neuronal apoptosis participate in the period of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Suppression of inflammation has recently been shown to reduce neuronal death and neurobehavioral dysfunction post SA
Autor:
Xin Zhang, Shengyin Lv, Qi Wu, Jiang Shao, Jin Xue, Qing-Rong Zhang, Li-Li Wen, Jing-Peng Liu, Xiang-Sheng Zhang
Publikováno v:
World Neurosurgery. 111:e362-e373
Aneurysmal subarachnoid hemorrhage (aSAH) is a severe cerebrovascular accident with high morbidity and mortality. The aim of this study is to investigate the relationship between level of inflammatory cytokines in cerebrospinal fluid (CSF) of aSAH pa
Autor:
Qiang Chen, Jing-Peng Liu, Wen-Zhong Hou, Ling-Yun Wu, Xiang-Sheng Zhang, Zong Zhuang, Yue Lu, Zhen-Nan Ye, Zi-Huan Zhang, Ce-Gang Liu, Hua-Sheng Zhang, Chun-Hua Hang
Publikováno v:
Human Pathology. 63:46-52
Glioma is the most common type of malignant neoplasm in the central nervous system, with high incidence and mortality rate. MicroRNAs, as a class of small noncoding RNAs, play an important role in carcinogenesis and correlate with glioma diagnosis an