Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Thomas S. Uldrick"'
Autor:
Suzanne George, Caroline Schenkel, S. Percy Ivy, Edward S. Kim, Gwynn Ison, Mark Stewart, Patricia A. Spears, Diana Merino Vega, Richard L. Schilsky, Thomas S. Uldrick, Alexander I. Spira, James L. Wade, Andrea Denicoff, Allison Magnuson, Raymond P. Perez, Suanna S. Bruinooge, R. Donald Harvey, Julia A. Beaver, William D. Tap
Publikováno v:
Clinical Cancer Research. 27:2394-2399
Purpose: Restrictive clinical trial eligibility criteria (EC) limit the number of patients who can enroll and potentially benefit from protocol-driven, investigational treatment plans and reduce the generalizability of trial results to the broader po
Autor:
George Anthony Komatsoulis, Suanna S. Bruinooge, Whitney Rhodes, Gwynn Ison, Richard L. Schilsky, Edward J. Stepanski, Elizabeth Garrett-Mayer, Robert S. Miller, Wendy S. Rubinstein, Edward S. Kim, Sean Khozin, Caroline Schenkel, R. Donald Harvey, Thomas S. Uldrick, Li Chen
Publikováno v:
Clinical Cancer Research. 27:2430-2434
Purpose: Cancer clinical trials often accrue slowly or miss enrollment targets. Strict eligibility criteria are a major reason. Restrictive criteria also limit opportunities for patient participation while compromising external validity of trial resu
Autor:
Kathryn Finch Mileham, Cassadie Moravek, Andrew S. Kennedy, Thomas S. Uldrick, E. Claire Dees, Caroline Schenkel, Scot Ebbinghaus, S. Percy Ivy, Jamie Renee Brewer, Atiqur Rahman, R. Donald Harvey, Vishal Bhatnagar, Elizabeth Ness
Publikováno v:
Clin Cancer Res
Purpose: Washout periods and concomitant medication exclusions are common in cancer clinical trial protocols. These exclusion criteria are often applied inconsistently and without evidence to justify their use. The authors sought to determine how was
Autor:
Kathryn Lurain, Matthew Lindsley, Armando C. Filie, Joseph M. Ziegelbauer, Robert Yarchoan, Wendell Miley, Maryalice Stetler-Stevenson, Thomas S. Uldrick, Nazzarena Labo, Hao-Wei Wang, Elena Cornejo-Castro, Vickie Marshall, Denise Whitby, Anaida Widell, Constance M. Yuan, Adam Rupert, Ramya Ramaswami
Publikováno v:
AIDS
OBJECTIVE To assess the cytokine and viral profiles of effusions and peripheral blood among patients diagnosed with HIV and Kaposi sarcoma herpesvirus [KSHV, also known as human herpesvirus 8 (HHV-8)]-associated conditions. DESIGN Retrospective compa
Autor:
Amrit Singh, Anthony P. Schwarer, Helen L. Partridge, Frits van Rhee, Daniel J. Arenas, David C. Fajgenbaum, Katie L. Stone, Mariko Okumura, Jason R. Ruth, Nelson Hamerschlak, Michael R. Betts, Thomas S. Uldrick, Gerald Wertheim, Christopher S. Nabel, Taku Kambayashi, Michael B. Jordan, Sheila K Pierson, Fabio Freire José, Alberto Sada Japp, Arthur H. Rubenstein, Adam D. Cohen, Ruth-Anne Langan, Vera P. Krymskaya
Publikováno v:
Journal of Clinical Investigation. 129:4451-4463
BACKGROUND Idiopathic multicentric Castleman disease (iMCD) is a hematologic illness involving cytokine-induced lymphoproliferation, systemic inflammation, cytopenias, and life-threatening multi-organ dysfunction. The molecular underpinnings of inter
Autor:
Priscila H. Goncalves, Thomas S. Uldrick, Mark N. Polizzotto, Ramya Ramaswami, Denise Whitby, Seth M. Steinberg, Giovanna Tosato, Anaida Widell, Robert Yarchoan, William D. Figg, Kathryn Lurain, Kathleen M. Wyvill
Publikováno v:
Clin Cancer Res
Purpose: VEGF-A is important in the pathogenesis of Kaposi sarcoma, and bevacizumab has a response rate of 31%. We explored the combination of bevacizumab with liposomal doxorubicin in patients with Kaposi sarcoma. Patients and Methods: Patients with
Autor:
Thomas S. Uldrick, Vishal N. Koparde, Anna P. Serquiña, Ramya Ramaswami, Takanobu Tagawa, Kathryn Lurain, Joseph M. Ziegelbauer, John L. Spouge, Shaojian Gao, Robert Yarchoan, Mileidy Gonzalez
Publikováno v:
Proceedings of the National Academy of Sciences. 115:12805-12810
Noncoding RNAs have substantial effects in host–virus interactions. Circular RNAs (circRNAs) are novel single-stranded noncoding RNAs which can decoy other RNAs or RNA-binding proteins to inhibit their functions. The role of circRNAs is largely unk
Autor:
Joanna Sztuba-Solinska, Elena M. Cornejo Castro, Nazzarena Labo, Lynne McNamara, Robert Yarchoan, Stuart F. J. Le Grice, Patrick MacPhail, Vickie Marshall, Karen Aleman, Kathleen M. Wyvill, Denise Whitby, Thomas S. Uldrick, Mark N. Polizzotto
Publikováno v:
Oncotarget
// Vickie A. Marshall 1 , Nazzarena Labo 1 , Joanna Sztuba-Solinska 2, 6 , Elena M. Cornejo Castro 1 , Karen Aleman 3 , Kathleen M. Wyvill 3 , Lynne McNamara 4 , Stuart F.J. Le Grice 2 , Robert Yarchoan 3 , Thomas S. Uldrick 3 , Patrick MacPhail 5 ,
Autor:
Matthew Painschab, Thomas S. Uldrick, Michalina A Montaño, Maganizo Chagomerana, Rachel A Bender Ignacio, Margaret Borok
Publikováno v:
Curr HIV/AIDS Rep
PURPOSE OF REVIEW: The relationship between antiretroviral therapy (ART) and cancer treatment outcomes among people living with HIV (PLWH) in low- and middle-income countries (LMICs) is complex and poorly understood for many cancers. We aimed to summ
Publikováno v:
Curr HIV/AIDS Rep
PURPOSE OF REVIEW: Immune checkpoint inhibitors targeting the programmed cell death-1 (PD-1) pathway are a class of anti-cancer immunotherapy agents changing treatment paradigms of many cancers that occur at higher rates in people living with HIV (PL