Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rossella Manfredini"'
Autor:
Laura Cortesi, Tommaso Trenti, Monica Pedroni, Elena Barbieri, Marco Marino, Fiammetta Biagiarelli, Elena Tenedini, Luca Roncucci, Sara Castellano, Rossella Manfredini, Pierluigi Iapicca, Lucia Artuso, Angela Toss, Mario Luppi, Fabio Celestini, Enrico Tagliafico
Publikováno v:
Diagnosis (Berlin, Germany)References. 9(1)
Objectives The Next Generation Sequencing (NGS) based mutational study of hereditary cancer genes is crucial to design tailored prevention strategies in subjects with different hereditary cancer risk. The ease of amplicon-based NGS library constructi
Autor:
Mario Cazzola, Alessandro M. Vannucchi, Chiara Paoli, Rossella Manfredini, Paola Guglielmelli, Elisa Rumi, Francesco Mannelli, Annalisa Pacilli, Sara Fiaccabrino, Giada Rotunno, Giada Brogi, Giovanni Barosi, Benedetta Sordi, Francesca Gesullo, Carmela Mannarelli, Ilaria M. Marone
Publikováno v:
Blood. 133:2802-2808
TO THE EDITOR: The discovery of prognostically informative mutations in patients with primary myelofibrosis (PMF)[1][1] prompted the development of mutation-enhanced risk scores.[2][2][⇓][3][⇓][4][⇓][5]-[6][6] Among these mutations, those in AS
Autor:
Chiara Rossi, Roberta Zini, Sebastiano Rontauroli, Samantha Ruberti, Zelia Prudente, Greta Barbieri, Elisa Bianchi, Simona Salati, Elena Genovese, Niccolò Bartalucci, Paola Guglielmelli, Enrico Tagliafico, Vittorio Rosti, Giovanni Barosi, Alessandro M. Vannucchi, Rossella Manfredini, the AGIMM (AIRC‐Gruppo Italiano Malattie Mieloproliferative) investigators
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 12, Iss 12, Pp 2102-2123 (2018)
Molecular Oncology, Vol 12, Iss 12, Pp 2102-2123 (2018)
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterized by an excessive production of pro-inflammatory cytokines resulting in chronic inflammation and genomic instability. Besides the driver mutations in JAK2, MPL, and CALR genes,
Autor:
Simona Salati, Zelia Prudente, Elena Genovese, Valentina Pennucci, Sebastiano Rontauroli, Niccolò Bartalucci, Carmela Mannarelli, Samantha Ruberti, Roberta Zini, Chiara Rossi, Elisa Bianchi, Paola Guglielmelli, Enrico Tagliafico, Alessandro M. Vannucchi, Rossella Manfredini, null on behalf of the AGIMM (AIRC Gruppo
Publikováno v:
Stem Cells and Development. 27:225-236
Calreticulin (CALR) is a chaperone protein that localizes primarily to the endoplasmic reticulum (ER) lumen where it is responsible for the control of proper folding of neo-synthesized glycoproteins and the retention of calcium. Recently, mutations a
Autor:
Chiara Carretta, Sebastiano Rontauroli, Greta Barbieri, Micaela Bergamaschi, Roberta Zini, Fausto Castagnetti, Rossella Manfredini, Agostino Tafuri, Samantha Ruberti, Chiara Rossi, Elena Genovese, Enrico Tagliafico, Roberto M. Lemoli, Valentina Salvestrini, Antonio Curti, Gianantonio Rosti, Simona Salati, Elisa Bianchi, Gabriele Gugliotta
Publikováno v:
Oncotarget
// Simona Salati 1 , Valentina Salvestrini 2 , Chiara Carretta 1 , Elena Genovese 1 , Sebastiano Rontauroli 1 , Roberta Zini 1 , Chiara Rossi 1 , Samantha Ruberti 1 , Elisa Bianchi 1 , Greta Barbieri 1 , Antonio Curti 2 , Fausto Castagnetti 2 , Gabri
miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes
Autor:
Anette-Gabriele Ziegler, Isabelle Serr, Adam M. Zahm, Saverio Bellusci, Katharina Gerlach, Martin G. Scherm, Victoria K. Salb, Rossella Manfredini, Benno Weigmann, Carolin Daniel, Jonathan Schug, Klaus H. Kaestner
Publikováno v:
Nat. Commun. 10:5697 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
In type 1 diabetes, the appearance of islet autoantibodies indicates the onset of islet autoimmunity, often many years before clinical symptoms arise. While T cells play a major role in the destruction of pancreatic beta cells, molecular underpinning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e536d3d68712489a059ba724008a1e14
https://hdl.handle.net/11380/1221487
https://hdl.handle.net/11380/1221487
Autor:
Rossella Manfredini, Simona Salati, Valentina Pennucci, Enrico Tagliafico, Paola Guglielmelli, Elisa Bianchi, Elena Enzo, Samantha Ruberti, Carmela Mannarelli, Alessandro M. Vannucchi, Niccolò Bartalucci, Elena Genovese, Chiara Carretta, Zelia Prudente, Chiara Rossi, Laura Calabresi, Sebastiano Rontauroli, Manjola Balliu, Roberta Zini
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Somatic mutations of calreticulin (CALR) have been described in approximately 60–80% of JAK2 and MPL unmutated Essential Thrombocythemia and Primary Myelofibrosis patients. CALR is an endoplasmic reticulum (ER) chaperone responsible for proper prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0feb88299b71898c389a3cd041c9973
https://hdl.handle.net/11380/1183743
https://hdl.handle.net/11380/1183743
Autor:
Federica Frezzato, Domenico Delia, Claudio Brancolini, Rossella Manfredini, Valentina Trimarco, Fabio Benedetti, Sonia Ciotti, Raffaella Picco, Elisa Bianchi, Gianpietro Semenzato, Andrea Sgorbissa, Livio Trentin, Andrea Tomasella
Publikováno v:
Oncotarget
// Andrea Tomasella 1 , Raffaella Picco 1 , Sonia Ciotti 1 , Andrea Sgorbissa 1 , Elisa Bianchi 2 , Rossella Manfredini 2 , Fabio Benedetti 3 , Valentina Trimarco 4 , Federica Frezzato 4 , Livio Trentin 4 , Gianpietro Semenzato 4 , Domenico Delia 5 ,
Publikováno v:
Blood. 127:1249-1259
Megakaryopoiesis is a complex, stepwise process that takes place largely in the bone marrow. At the apex of the hierarchy, hematopoietic stem cells undergo a number of lineage commitment decisions that ultimately lead to the production of polyploid m
Autor:
Rossella Manfredini, Alberto L. Horenstein, Roberta Zini, Valeria Quarona, Fabio Malavasi, Roberto Gambari, Nicoletta Bianchi, Davide Ferrari, Antonella Chillemi
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology
Frontiers in Pharmacology
Cytokine-induced killer (CIK) cells, a heterogeneous T cell population obtained by in vitro differentiation of peripheral blood mononuclear cells (PBMC), represent a promising immunological approach in cancer. Numerous studies have explored the role