Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Pankaj Vats"'
Autor:
Namita G. Hattangady, Pankaj Vats, Thomas J. Giordano, Juilee Rege, Scott A. Tomlins, Kazutaka Nanba, Amy R Blinder, Chia Jen Liu, William E. Rainey, Tobias Else, Chandan Kumar-Sinha
Publikováno v:
Hypertension. 75:645-649
Driver somatic mutations for aldosterone excess have been found in ≈90% of aldosterone-producing adenomas (APAs) using an aldosterone synthase (CYP11B2)-guided sequencing approach. In the present study, we identified a novel somatic CACNA1H mutatio
Autor:
Jean Monlong, Claude Sinner, Dreycey Albin, Ann M Mc Cartney, Justin N. Vaughn, Arun Subramaniyan, Advait Balaji, Medhat Mahmoud, Moez Dawood, Qiandong Zeng, Eric T. Dawson, Najeeb Syed, Zev N. Kronenberg, Todd J. Treangen, Daniel L Cameron, Timothy Hefferon, Mark Chaisson, Ahmad Al Khleifat, Michael M. Khayat, Hakeem Almabrazi, Moritz Smolka, Fritz J. Sedlazeck, Evan Biederstedt, Alejandro Rafael Gener, Rupesh K. Kesharwani, Ahmed Arslan, James M Havrilla, Arda Soylev, Sagayamary Sagayaradj, Pamella Tater, Christopher Dunn, Fawaz Dabbaghie, Daniela C. Soto, Pankaj Vats, Barry Zorman, Wouter De Coster, Neha Tadimeti, Yunxi Liu, Ben Busby, Tsung-Yu Lu, Gaojianyong Wang, Kimberley Billingsley, Stephen J. Price, Kimberly Walker, Elbay Aliyev, Haowei Du, Daniel Paiva Agustinho, Divya Kalra, Tingting Zhao, Maximillian Marin, Adam C. English, Jingwen Ren, Bryce Kille, Shangzhe Zhang, Sairam Behera, Michael Jochum, Rocio Esteban, Angad Jolly, Nicolae Sapoval, Chunxiao Liao, Joyjit Daw, Chen-Shan Chin
Publikováno v:
F1000Research
In October 2020, 62 scientists from nine nations worked together remotely in the Second Baylor College of Medicine & DNAnexus hackathon, focusing on different related topics on Structural Variation, Pan-genomes, and SARS-CoV-2 related research. The o
Autor:
Kathryn McFadden, Arul M. Chinnaiyan, Andrew H. Zureick, Bailey Anderson, Sriram Venneti, Lili Zhao, Robert J. Lonigro, Karin M. Muraszko, Bernard L. Marini, Brendan Mullan, Patricia L. Robertson, Xuhong Cao, Pankaj Vats, Marcin Cieslik, Rajen Mody, Carl Koschmann, Jessica Everett, Paul E. McKeever, Sandra Camelo-Piragua, Yi-Mi Wu, Marcia Leonard, Hugh J. L. Garton, Cormac O. Maher, Andrew P. Lieberman, Katayoon Kasaian, Kevin Frank, John R. Prensner, Dan R. Robinson, Chandan Kumar-Sinha
Publikováno v:
JCO Precis Oncol
Purpose Brain tumors have become the leading cause of cancer-related mortality in young patients. Novel effective therapies on the basis of the unique biology of each tumor are urgently needed. The goal of this study was to evaluate the feasibility,
Autor:
Nicole D. Lee, Pankaj Vats, Saravana M. Dhanasekaran, Fengyun Su, Rohit Mehra, Arul M. Chinnaiyan, Robert J. Lonigro, Kumpati Premkumar, Jesse K. McKenney, Kiril Trpkov, Xuhong Cao
Publikováno v:
European Urology. 74:483-486
Renal cell carcinomas (RCC) with overlapping histomorphologic features poses diagnostic challenges. This is exemplified in RCCs with eosinophilic cytoplasm that include eosinophilic solid and cystic RCC (ESC RCC), RCCs in germline aberrations of tube
Autor:
Pankaj Vats, Tobias Else, Kazutaka Nanba, Amy R Blinder, Samuel W. Plaska, Thomas J. Giordano, Aaron M. Udager, Chandan Kumar-Sinha, Juilee Rege, William E. Rainey
Publikováno v:
Journal of the Endocrine Society
Somatic mutations driving aldosterone production have been identified in approximately 90% of aldosterone-producing adenomas (APAs) using an aldosterone synthase (CYP11B2) immunohistochemistry (IHC)-guided DNA sequencing approach. In the present stud
Autor:
Daniel L. Hertz, Erika Mora, Pankaj Vats, Bailey Anderson, Yi-Mi Wu, Rajen Mody, Kevin Frank, Andrew Glatz, Amy L. Pasternak, Dan R. Robinson, Robert J. Lonigro, Arul M. Chinnaiyan, Erica Rabban
Publikováno v:
JCO Precis Oncol
Purpose Evidence-based guidelines inform treatment decisions for patients for whom germline genetic information is available. Our real-time tumor sequencing program, which makes precision treatment decisions for patients with cancer, produces matched
Autor:
Ronald F. Siebenaler, Jean Ching-Yi Tien, Vijaya L. Dommeti, Rahul Mannan, Stephanie J. Ellison, Sethuramasundaram Pitchiaya, Xuhong Cao, Seema Chugh, Howard C. Crawford, Ingrid J. Apel, Jessica Waninger, Chandan Kumar-Sinha, Andrew Goodrum, Sanjana Eyunni, Sylvia Zelenka-Wang, Pankaj Vats, Yuping Zhang, Malay Mody, Jiaqi Shi, Xiaoming Wang, Alice Xu, Sunita Shankar, John J.G. Tesmer, Arul M. Chinnaiyan
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Both KRAS and EGFR are essential mediators of pancreatic cancer development and interact with Argonaute 2 (AGO2) to perturb its function. Here, in a mouse model of mutant KRAS-driven pancreatic cancer, loss of AGO2 allows precursor lesion (PanIN) for
Autor:
Pankaj Vats, Rajen Mody, Dan R. Robinson, Jonathan Bender, Bailey Anderson, Chandan Kumar-Sinha, Qing Li, Yi-Mi Wu, Marcin Cieslik, Gina Ney, Arul M. Chinnaiyan
Background Cancer remains the number one cause of disease-related mortality in children, and despite advances in the molecular understanding of leukemia and targeted therapies, refractory leukemia remains a leading cause of death. It therefore is ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0667ec3a054ed0e4cdd3a930c95a7a63
https://europepmc.org/articles/PMC7036640/
https://europepmc.org/articles/PMC7036640/
Autor:
Gavin Ha, Roman Gulati, Jonathan Reichel, Pankaj Vats, Andrew J. Armstrong, Colin C. Pritchard, Arul M. Chinnaiyan, Vaibhav G. Patel, Rana R. McKay, Anna C. H. Hoge, Ajjai Alva, William Oh, R. Bruce Montgomery, Deepak Kilari, Landon C. Brown, Michael T. Schweizer, Tanya B. Dorff
Publikováno v:
JCO Precis Oncol
PURPOSE Translational studies have shown that CDK12 mutations may delineate an immunoresponsive subgroup of prostate cancer, characterized by high neo-antigen burden. Given that these mutations may define a clinically distinct subgroup, we sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5753fd80165dc1328ffe28ce5f2d4a
https://europepmc.org/articles/PMC7363399/
https://europepmc.org/articles/PMC7363399/
Publikováno v:
Methods in Molecular Biology ISBN: 9781493999033
RNA-seq provides an efficient and sensitive methodology to identify fusion transcripts in cancer tissues. Chimeric reads mapping across two different genes represent potential gene fusions. Various methodologies have been implemented in the detection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aafc25bb4d3c2ae9de1a6af24fac07b
https://doi.org/10.1007/978-1-4939-9904-0_5
https://doi.org/10.1007/978-1-4939-9904-0_5