Zobrazeno 1 - 10
of 1 242
pro vyhledávání: '"Hong Zhang"'
Publikováno v:
Seminars in Cancer Biology. 83:261-268
Thyroid cancer is not among the top cancers in terms of diagnosis or mortality but it still ranks fifth among the cancers diagnosed in women. Infact, women are more likely to be diagnosed with thyroid cancer than the males. The burden of thyroid canc
Autor:
Hongwei Yu, Zhenning He, Yanqing Zhu, Hong Zhang, Ilayaraja Muthuramu, Lili Wang, James M. Wilson, Suryanarayan Somanathan, Anna Tretiakova, Peter Bell
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 1-10 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 1-10 (2021)
Gene therapy for hypercholesterolemia offers the potential to sustainably ameliorate disease for life with a single dose. In this study, we demonstrate the combinatorial effects of codon and vector optimization, which significantly improve the effica
Autor:
Chun-Yu Deng, Zhiming Ye, Xia Chen, Caoshuai Dou, Yingzhen Wen, Zhiwen Lian, Wenjian Wang, Juan Hu, Sijia Li, Wei Shi, Zhuo Li, Ruizhao Li, Guibao Ke, Qianmei Zhang, Jianchao Ma, Ruyi Liao, Xueqin Chen, Lixia Xu, Ting Lin, Wei Dong, Li Zhang, Yue Du, Houqin Xiao, Yuanhan Chen, Bohou Li, Fengxia Zhang, Chaosheng He, Zhonglin Feng, Shuangshuang Zhu, Shuangxin Liu, Jie Xiao, Xingchen Zhao, Minghao Zheng, Xinling Liang, Su-Juan Kuang, Hong Zhang
Publikováno v:
Kidney International. 100:377-390
Receptor activator of NF-κB (RANK) expression is increased in podocytes of patients with diabetic nephropathy. However, the relevance of RANK to diabetic nephropathy pathobiology remains unclear. Here, to evaluate the role of podocyte RANK in the de
Publikováno v:
FEBS Open Bio, Vol 11, Iss 7, Pp 1930-1940 (2021)
FEBS Open Bio
FEBS Open Bio
Graves’ ophthalmopathy, also known as thyroid‐associated orbitopathy (TAO), is the most common inflammatory eye disease in adults. The most common etiology for TAO is Graves’ disease (GD); however, proteomic research focusing on differences bet
Publikováno v:
Physiol Res
Gastrointestinal motility was disturbed in W/Wv, which were lacking of interstitial cells of Cajal (ICC). In this study, we have investigated the role of arecoline hydrobromide (AH) on smooth muscle motility in the jejunum of W/Wv and wild-type (WT)
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Wikstroemia (Thymelaeaceae) is a diverse genus that extends from Asia to Australia and has been recorded on the Hawaiian Islands. Despite its medicinal properties and resource utilization in pulp production, genetic studies of the species in this imp
Publikováno v:
Drug Discov Today
AR is an oncogenic driver of hepatocellular carcinoma but AR-targeted therapy is limited by feedback activation of the AKT-mTOR pathway. Co-targeting of mTORC1 and AR might be an effective approach to HCC treatment. Hepatocellular carcinoma (HCC) is
Autor:
Xiaoyan Mao, Qiaoli Li, Biaobang Chen, Jijun Hu, Lin Zhao, Wenjing Wang, Li Jin, Jing Du, Jie Dong, Hong Zhang, Da Li, Lin He, Xiaoxi Sun, Zhihua Zhang, Qing Sang, Yanping Kuang, Junhua Zhu, Jing Fu, Zhou Zhou, Jian Mu, Yiming Sun, Weijie Wang, Ling Wu, Lei Wang, Yang Zeng
Publikováno v:
Human Reproduction. 36:2371-2381
STUDY QUESTION Are any novel mutations and corresponding new phenotypes, other than recurrent hydatidiform moles, seen in patients with MEI1 mutations? SUMMARY ANSWER We identified several novel mutations in MEI1 causing new phenotypes of early embry
Publikováno v:
Inflammation. 44:1982-1992
Although natural killer T cells (NKT cells) are altered in obese asthmatic mice, their function remains completely unclear. To further explore the potential mechanism of NKT cells in airway inflammation of obesity-associated asthma, we examined the e
Publikováno v:
Journal of Molecular Histology. 52:643-650
Lung diseases, including asthma, pose a serious global health issue. Loss of mitochondrial function and decreased mitochondrial biogenesis play pivotal roles in the initiation and progression of chronic lung diseases. Thus, maintaining mitochondrial