Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hays Arnold"'
Autor:
Hays Arnold, Andrew J. Muir, Alexander J. Thompson, Alex M. DePaoli, Lei Ling, Stephen J. Rossi, Alan Wigg, Elizabeth J. Carey, Martin Weltman, Barbara A. Leggett, Marlyn J. Mayo
Publikováno v:
Hepatology Communications, Vol 2, Iss 9, Pp 1037-1050 (2018)
Hepatology Communications
Hepatology Communications
Patients with primary biliary cholangitis (PBC) who had an inadequate response to ursodiol have few treatment options. Alkaline phosphatase (ALP) and bilirubin levels correlate with the risk of liver transplant or death in PBC patients. Fibroblast gr
Autor:
Stephen J. Rossi, Mary E. Rinella, Mark J. Jaros, Alex M. DePaoli, Marcelo Kugelmas, Stephen A. Harrison, Manal F. Abdelmalek, Hays Arnold, James F. Trotter, Mustafa R. Bashir, ing L, Angelo H. Paredes, Rohit Loomba
Publikováno v:
The Lancet. 391:1174-1185
Non-alcoholic steatohepatitis is a chronic liver disease characterised by the presence of hepatic steatosis, inflammation, and hepatocellular injury, for which no Food and Drug Administration (FDA)-approved treatment exists. FGF19 is a hormone that r
Autor:
Stephen H. Caldwell, Saumya Jayakumar, Anna Mae Diehl, G. Mani Subramanian, Ling Han, John G. McHutchison, Zachary Goodman, Nezam H. Afdhal, C. Stephen Djedjos, Eric Lawitz, Parvez S. Mantry, Rohit Loomba, Hays Arnold, Robert P. Myers, Michael Charlton
Publikováno v:
Hepatology. 67:549-559
Inhibition of apoptosis signal-regulating kinase 1, a serine/threonine kinase, leads to improvement in inflammation and fibrosis in animal models of nonalcoholic steatohepatitis. We evaluated the safety and efficacy of selonsertib, a selective inhibi
Autor:
Hays Arnold, Robert P. Myers, Saumya Jayakumar, C. Stephen Djedjos, Michael Charlton, Michael S. Middleton, Magdy Elkhashab, Manal F. Abdelmalek, Parvez S. Mantry, Anna Mae Diehl, Ren Xu, Stephen H. Caldwell, Nezam H. Afdhal, Ling Han, Reem Ghalib, Claude B. Sirlin, Kris V. Kowdley, Rohit Loomba, Eric Lawitz, Zachary Goodman, G. Mani Subramanian
Publikováno v:
Journal of hepatology, vol 70, iss 1
Jayakumar, Saumya; Middleton, Michael S; Lawitz, Eric J; Mantry, Parvez S; Caldwell, Stephen H; Arnold, Hays; et al.(2019). Longitudinal correlations between MRE, MRI-PDFF, and liver histology in patients with non-alcoholic steatohepatitis: Analysis of data from a phase II trial of selonsertib. JOURNAL OF HEPATOLOGY, 70(1), 133-141. doi: 10.1016/j.jhep.2018.09.024. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/96b1p0vj
Jayakumar, Saumya; Middleton, Michael S; Lawitz, Eric J; Mantry, Parvez S; Caldwell, Stephen H; Arnold, Hays; et al.(2019). Longitudinal correlations between MRE, MRI-PDFF, and liver histology in patients with non-alcoholic steatohepatitis: Analysis of data from a phase II trial of selonsertib. JOURNAL OF HEPATOLOGY, 70(1), 133-141. doi: 10.1016/j.jhep.2018.09.024. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/96b1p0vj
Background & Aims Non-invasive tools for monitoring treatment response and disease progression in non-alcoholic steatohepatitis (NASH) are needed. Our objective was to evaluate the utility of magnetic resonance (MR)-based hepatic imaging measures for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da08a6210691f138234a9000638dd431
https://escholarship.org/uc/item/96b1p0vj
https://escholarship.org/uc/item/96b1p0vj
Autor:
Stephen A. Harrison, Mary E. Rinella, Manal F. Abdelmalek, Lei Ling, James F. Trotter, Marcelo Kugelmas, Hays Arnold, Mustafa R. Bashir, Angelo H. Paredes, Alex M. DePaoli, Rohit Loomba, Stephen J. Rossi
Publikováno v:
Journal of Hepatology. 66:S92-S93