Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fuping You"'
Publikováno v:
European Journal of Immunology. 51:1641-1651
Emerging life-threatening viruses have posed great challenges to public health. It is now increasingly clear that epigenetics plays a role in shaping host-virus interactions and there is a great need for a more thorough understanding of these intrica
ELF4 facilitates innate host defenses against Plasmodium by activating transcription of Pf4 and Ppbp
Publikováno v:
Journal of Biological Chemistry. 294:7787-7796
Platelet factor 4 (PF4) is an anti-Plasmodium component of platelets. It is expressed in megakaryocytes and released from platelets following infection with Plasmodium. Innate immunity is crucial for the host anti-Plasmodium response, in which type I
Autor:
Ting Zhang, Jie Wang, Tianxu Liu, Fengmin Lu, Huiling Zheng, Jia Liu, Fuping You, Congle Shen, Xiangmei Chen, Jun Zou, Guiwen Guan, Jing Zhang, Xiaoyu Feng, Deyao Li, Xiaobin Zao, Jin Cheng
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Oncoimmunology
article-version (VoR) Version of Record
Oncoimmunology
article-version (VoR) Version of Record
Nuclear factor of activated T cells 3 (NFATc3) has been reported to upregulate type I interferons (IFNs) expression, and the abnormal expression and activation of NFATc3 were closely related to tumorigenesis. However, the potential function of NFATc3
Autor:
Leilei Wang, Duomeng Yang, Tingting Geng, Jesse Hwang, Penghua Wang, Long Yang, Shu Zhu, Harshada Ketkar, Fuping You, Tao Lin, Richard A. Flavell, Erol Fikrig, Jinzhu Ma, Gong Cheng, Jianfeng Dai, Guang Yang, Anthony T. Vella, Yanlin Wang
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Macrophage scavenger receptor 1 (MSR1) mediates the endocytosis of modified low-density lipoproteins and plays an important antiviral role. However, the molecular mechanism underlying MSR1 antiviral actions remains elusive. We report that MSR1 activa
Autor:
Leilei Wang, Gong Cheng, Shuang Cui, Jinzhu Ma, Rongtuan Lin, Fuping You, Long Yang, Harshada Ketkar, Toyoshi Fujimoto, Penghua Wang, Dana G. Mordue, Tingting Geng, Erol Fikrig, Guang Yang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
The ubiquitin regulatory X domain-containing proteins (UBXNs) are likely involved in diverse biological processes. Their physiological functions, however, remain largely unknown. Here we present physiological evidence that UBXN3B positively regulates
Autor:
Xiang Gao, Yunfei Li, Hongqiang Du, Chunxia Jing, Xiaohong Ye, Peng Li, Shengde Liu, Meiling Ou, Fuping You, Feng Shao, Guang Yang, Lili Cao, Siji Li, Baohuan Zhang, Yingchi Zhao, Penghua Wang, Peiyan Wang
Toxoplasma gondii is an important neurotropic pathogen that establishes latent infections in humans that can cause toxoplasmosis in immunocompromised individuals. It replicates inside host cells and has developed several strategies to manipulate host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289775e2fcac04c3781017c8381babce
https://europepmc.org/articles/PMC6851339/
https://europepmc.org/articles/PMC6851339/
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 8, p e0200385 (2018)
PLoS ONE, Vol 13, Iss 8, p e0200385 (2018)
The innate immune system plays a critical role in the initial antiviral response. However, the timing and duration of these responses must be tightly regulated during infection to ensure appropriate immune cell activation and anti-viral defenses. Her
Autor:
Shuang Cui, Huaping Sun, Tong Liu, Guang Yang, Hongqiang Du, Li Yu, Jingxuan Chen, Baoping Jiang, Fuping You, Weiwei Tao
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
E. fischeriana has long been used as a traditional Chinese medicine. Recent studies reported that some compounds of E. fischeriana exhibited antimicrobial and immune enhance activity. Innate immune system is essential for the immune surveillance of i
Autor:
Jim Auer, Richard E. Sutton, Erol Fikrig, Yani Hu, Kaitlin C. O'Boyle, Sagar Raju, Fuping You, Penghua Wang
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 2, p e1006187 (2017)
PLoS Pathogens, Vol 13, Iss 2, p e1006187 (2017)
UBXN proteins likely participate in the global regulation of protein turnover, and we have shown that UBXN1 interferes with RIG-I-like receptor (RLR) signaling by interacting with MAVS and impeding its downstream effector functions. Here we demonstra