Zobrazeno 1 - 10
of 400
pro vyhledávání: '"FANG YANG"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Cathepsin A (CTSA) is a lysosomal protease that regulates galactoside metabolism. The previous study has shown CTSA is abnormally expressed in various types of cancer. However, rarely the previous study has addressed the role of CTSA in hepatocellula
Autor:
Mo-Xian Chen, Jing-Fang Yang, Yuan Tian, Qin-Lai Liu, Jianhua Zhang, Yinggao Liu, Yu-Zhen Zhao, Chen Chen, Shaoming Zhou, Tao Fan, Das Debatosh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Eukaryotic cells can expand their coding ability by using their splicing machinery, spliceosome, to process precursor mRNA (pre-mRNA) into mature messenger RNA. The mega-macromolecular spliceosome contains multiple subcomplexes, referred to as small
Autor:
Fei Ling, Xiaomin Liu, Xiuqing Zhang, Xiao Liu, Shilong Zhong, Zhiwei Zhang, Fang Yang, Huanming Yang, Xu Huaiqian, Wai-Ho Mak, Xun Xu, Jian Wang, Tao Zhang, Hanshi Xu, Huijue Jia, Zheng Su, Qingshan Geng, Jiyan Chen
Publikováno v:
The Pharmacogenomics Journal
ImportanceAlthough a few studies have reported the effects of several polymorphisms on major adverse cardiovascular events (MACE) in patients with acute coronary syndromes (ACS) and those undergoing percutaneous coronary intervention (PCI), these gen
Publikováno v:
Cancer Medicine, Vol 10, Iss 12, Pp 3919-3927 (2021)
Cancer Medicine
Cancer Medicine
Background Core needle biopsy (CNB) has become the most common tissue sampling modality for pathological diagnosis of peripheral lung nodules. However, approximately 10% of pulmonary CNB specimens cannot be unambiguously diagnosed, even with auxiliar
Autor:
Yin Huang, Fengguo Xu, Xiaoying Deng, Fang Yang, Zunjian Zhang, Linling Guo, Peifang Liu, Xinyue Yu, Yuan Tian
Publikováno v:
Amino Acids. 53:893-901
The nervous system disorders caused by doxorubicin (DOX) are among the severe adverse effects that dramatically reduce the quality of life of cancer survivors. Astragali Radix (AR), a popular herbal drug and dietary supplement, is believed to help tr
Autor:
Xiaosong Rao, Yu Zhang, Yiran Chen, Fang Yang, Ziwei Guo, Jing Zhao, Li Li, Li Lin, Gaoda Ju, Xiaomin Lv, Weiran Xu, Jun Liang, Tao Xing
Publikováno v:
Biomarkers in Medicine. 15:497-508
Background: There was increasing evidence showing that ARID1A alterations correlated with higher tumor mutational burden, but there were limited studies focusing on the adaptive mechanisms for tumor cells to survive under excessive genomic alteration
Publikováno v:
Drug Design, Development and Therapy
Wenjuan Feng,1,2 Longyun Nie,3 Xiaoyu Wang,4 Fang Yang,1 Pan Pan,5 Xiaohui Deng1 1Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, Peo
Autor:
Wenhua Lei, Yan-Biao Liao, Dan Xiao, Tianyi Qu, Junli Li, Mao Chen, Fang-Yang Huang, Guoyong Li, Li Chen, Changming Li, Jialiang Zhang, Jiahao Zhao, Hao Zhou
Publikováno v:
Journal of Cellular and Molecular Medicine
MARCH5 is a critical regulator of mitochondrial dynamics, apoptosis and mitophagy. However, its role in cardiovascular system remains poorly understood. This study aimed to investigate the role of MARCH5 in endothelial cell (ECs) injury and the invol
Publikováno v:
Drug Design, Development and Therapy
Yue Xu,1,* Weiyin Chen,1,* Zeran Chen,2 Mengyuan Huang,1 Fang Yang,1 Yang Zhang1 1Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, People’s Republic of China; 2School of Medical and Life Sciences, Chengdu University
Autor:
Chien-Yun Lee, Hui-Chih Hung, Chi-Li Lin, Ju-Yi Hsieh, Yi-Liang Liu, Guang-Yaw Liu, Yi-Fang Yang
Publikováno v:
Journal of Cellular Physiology. 236:5646-5663
This study reveals an uncovered mechanism for the regulation of polyamine homeostasis through protein arginyl citrullination of antizyme (AZ), a natural inhibitor of ornithine decarboxylase (ODC). ODC is critical for the cellular production of polyam