Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Corinna Schlosser"'
Autor:
Manuela Carola Dürr, Sven Berger, Alexander Wiedenmann, Christine Rothe, Rachida Siham Bel Aiba, Ulrich Moebius, Corinna Schlosser, Marlon Hinner, Julia Schüler, Gabriele Matschiner, Louis Matis, Andrea Allersdorfer, Shane Olwill, Thomas Jaquin
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(19)
Purpose: 4-1BB (CD137) is a key costimulatory immunoreceptor and promising therapeutic target in cancer. To overcome limitations of current 4-1BB–targeting antibodies, we have developed PRS-343, a 4-1BB/HER2 bispecific molecule. PRS-343 is designed
Autor:
Nils Schweingruber, Christine Stadelmann, Dirk Fitzner, Marta Zagrebelsky, Jens Frahm, Francesca Odoardi, Brit Mollenhauer, Takashi Watanabe, Henrike J. Fischer, Corinna Schlosser, Arianna Merlini, Dmitri Lodygin, Michael Haberl, Moritz Hermann, Cassandra Flügel-Koch, Hsin-Fang Chang, Holger M. Reichardt, Sebastian Kügler, Alexander Flügel, Henrike Körner
Publikováno v:
Nature
The grey matter is a central target of pathological processes in neurodegenerative disorders such as Parkinson’s and Alzheimer’s diseases. The grey matter is often also affected in multiple sclerosis, an autoimmune disease of the central nervous
Autor:
Louis Matis, Rachida-Siham Bel Aiba, Sven Berger, Marlon Hinner, Shane Olwill, Andrea Allersdorfer, Corinna Schlosser, Christine Rothe, Manuela Carola Dürr, Thomas Jaquin
Publikováno v:
Cancer Research. 77:3673-3673
Background. 4-1BB (CD137) is a key costimulatory immunoreceptor and a highly promising therapeutic target in cancer. To overcome toxicity and efficacy limitations of current 4-1BB targeting antibodies, we have developed PRS-343, a 4-1BB/HER2 bispecif
Autor:
Thomas Jaquin, Gabriele Matschiner, Julia Schüler, R.S. Bel Aiba, Corinna Schlosser, Shane A. Olwill, Andrea Allersdorfer, Sven Berger, Ulrich Moebius, Christine Rothe, Alexander Wiedenmann, Marlon Hinner
Publikováno v:
European Journal of Cancer. 69:S99
Autor:
Gabriele Matschiner, Corinna Schlosser, Sven Berger, Marlon Hinner, Ulrich Moebius, Christine Rothe, Alexander Wiedenmann, Andrea Allersdorfer, Rachida-Siham Bel Aiba, Shane Olwill
Publikováno v:
Cancer Research. 76:556-556
Background. CD137 (4-1BB) is a key costimulatory immunoreceptor and a member of the TNF-receptor (TNFR) superfamily. While multiple lines of evidence show that CD137 is a highly promising therapeutic target in cancer, current mAb-based approaches are