Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Cheng Fan"'
Autor:
Gaurav Mehta, Gary L. Johnson, Lynn Chollet-Hinton, Stuart R. Jefferys, Joel S. Parker, Andres Forero-Torres, Timothy J. Stuhlmiller, Ian E. Krop, Xiaping He, Charles M. Perou, Kristalyn K. Gallagher, Noah Sciaky, Daniel R. Goulet, Steven P. Angus, Alastair M. Thompson, Maki Tanioka, J. Felix Olivares-Quintero, Cheng Fan, Lisa A. Carey, Rashmi Krishna Murthy, Darshan Singh, Matthew G. Soloway, H. Shelton Earp, Xin Chen, Jon S. Zawistowski, Patricia A. Spears, Michael L. Gatza, Naim U. Rashid, Michael P. East, Samantha M. Bevill
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-15 (2021)
Inhibition of the HER2/ERBB2 receptor is a keystone to treating HER2-positive malignancies, particularly breast cancer, but a significant fraction of HER2-positive (HER2+) breast cancers recur or fail to respond. Anti-HER2 monoclonal antibodies, like
Autor:
Hsin-Fang Tu, Ming-Shyue Lee, Geen-Dong Chang, Santiago Ramón-Maiques, Chia-Chi Ku, Der-Yen Lee, Chao-Chi Ho, Hsin-Ying Lin, Ching-Tai Lee, Francisco Del Caño-Ochoa, Chun-Jung Ko, Ya-Hui Chuang, I-Chun Chen, Shao-Wei Lan, Hsin-Hsien Lin, Cheng-Fan Lee
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
13 páginas, 7 figuras
Current clinical trials of combined EGFR-tyrosine kinase inhibitors (TKI) and immune checkpoint blockade (ICB) therapies show no additional effect. This raises questions regarding whether EGFR-TKIs attenuate ICB-enhanced C
Current clinical trials of combined EGFR-tyrosine kinase inhibitors (TKI) and immune checkpoint blockade (ICB) therapies show no additional effect. This raises questions regarding whether EGFR-TKIs attenuate ICB-enhanced C
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
Increasing evidence suggests that abnormal regulation of neurotrophic factors is involved in the etiology and pathogenesis of Autism Spectrum Disorder (ASD). However, clinical data on neurotrophic factor levels in children with ASD were inconsistent.
Autor:
Federico Rojo, Kevin R. Mott, Jeffery M. Rosen, Juan Miguel Cejalvo, Octavio Burgues, Susana García-Recio, Lisa A. Carey, Aleix Prat, Eduardo Martínez de Dueñas, Fara Brasó-Maristany, Alisha R. Coffey, Joel S. Parker, Ana Lluch, Xiaping He, Sara R. Selitsky, Charles M. Perou, Cheng Fan, Daniel P. Hollern, Joseph P. Garay, Michael P. East, Aatish Thennavan, Patricia Galván, David Marron, Joan Albanell, Gary L. Johnson
Publikováno v:
J Clin Invest
JOURNAL OF CLINICAL INVESTIGATION
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-FHPC. Repositorio Institucional de Producción Científica de la Fundación del Hospital Provincial de Castellón
JOURNAL OF CLINICAL INVESTIGATION
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-FHPC. Repositorio Institucional de Producción Científica de la Fundación del Hospital Provincial de Castellón
Mechanisms driving tumor progression from less aggressive subtypes to more aggressive states represent key targets for therapy. We identified a subset of luminal A primary breast tumors that give rise to HER2-enriched (HER2E) subtype metastases, but
Autor:
Chun-Jung Lin, Vitaly Margulis, Bing Guan, Andrew Dang, Junhang Luo, Fei Li, Ji‐Ming Bao, Elizabeth Hernandez, Cheng-Fan Lee, Wanlong Tan, Jer Tsong Hsieh, Vandana Panwar, Payal Kapur, Junjie Cen, Boris Feldkoren, Qiang Dang, Rolf A. Brekken, U-Ging Lo
Publikováno v:
Journal of Cellular Physiology. 236:1926-1938
Aberrant expression of transforming growth factor-β1 (TGF-β1) is associated with renal cell carcinoma (RCC) progression by inducing cancer metastasis. However, the downstream effector(s) in TGF-β signaling pathway is not fully characterized. In th
Autor:
Mei-Ju May Chen, Cheng-Fan Lee, Hsin-Fang Tu, Ting-Wei Hsu, Chun-Jung Ko, Ming-Shyue Lee, Hsin-Ying Lin, Cheng-Chung Huang, Ting-Feng Hsiao, Hsin-Hsien Lin, Shang-Ru Wu, Shao-Wei Lan, Pei-Wen Hsiao, Hsiang-Po Huang
Publikováno v:
Oncogene
TMPRSS2 is an important membrane-anchored serine protease involved in human prostate cancer progression and metastasis. A serine protease physiologically often comes together with a cognate inhibitor for execution of proteolytically biologic function
Publikováno v:
Neurochemical Research. 45:1888-1901
Selenium has been shown to possess antioxidant and neuroprotective effects by modulating mitochondrial function and activating mitochondrial biogenesis. Our previous study has also suggested that selenium protected neurons against glutamate toxicity
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 520
Background Conventional coagulation assays (CCAs) are of limited value in the assessment of coagulation status in patients with deep vein thrombosis (DVT). We aimed to compare thromboelastography (TEG) and CCAs in identifying DVT and evaluating coagu
Autor:
Longxian Zhang, Yu-Xin Wang, Xi Chen, Xin Yang, Guang-Hui Zhao, Xian-Cheng Fan, Jun-Ke Song, Xue-Mei Wu
Publikováno v:
Parasites & Vectors
Parasites & Vectors, Vol 14, Iss 1, Pp 1-12 (2021)
Parasites & Vectors, Vol 14, Iss 1, Pp 1-12 (2021)
Background Cryptosporidium baileyi is an economically important zoonotic pathogen that causes serious respiratory symptoms in chickens for which no effective control measures are currently available. An accumulating body of evidence indicates the pot
Autor:
Yue Liu, Xu Wang, Ran Zhang, De-Pei Liu, De-Long Hao, Zhu-Qin Zhang, Peng Zhang, Guang-Yuan Xiao, Jia-Hua Qu, Jian-Fei Pei, Hou-Zao Chen, Yan Xie, Peng-Cheng Fan, Tao Zhang, Ye Su, Bing Liu, Xiao-Man Wang, Ping Xu
Publikováno v:
iScience, Vol 17, Iss, Pp 155-166 (2019)
iScience
iScience
Summary Both caloric restriction (CR) and mitochondrial proteostasis are linked to longevity, but how CR maintains mitochondrial proteostasis in mammals remains elusive. MicroRNAs (miRNAs) are well known for gene silencing in cytoplasm and have recen