Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Amir R Afshari"'
Publikováno v:
BioMed Research International, Vol 2021 (2021)
Background. Colorectal cancer (CRC) is recognized as one of the most common malignancies with a high mortality rate worldwide, supporting the necessity for an effective novel antitumor drug to improve current therapy’s effectiveness. Substance P (S
Publikováno v:
Journal of Oncology, Vol 2020 (2020)
One of the most lethal forms of CNS pathologies is glioblastoma multiforme (GBM) that represents high invasiveness, uncontrolled proliferation, and angiogenic features. Its invasiveness is responsible for the high recurrence even after maximal surgic
Autor:
Sajad Sahab-Negah, Mohammad Jalili-Nik, Fatemeh Ariakia, Sahar Salehi, Ghadir Rajabzadeh, Amir R Afshari, Fariborz Samini, Ali Gorji
Publikováno v:
Molecular Neurobiology
Using a novel curcumin-loaded niosome nanoparticle (CM-NP), the present study was designed to evaluate the effect of curcumin on human glioblastoma stem-like cells (GSCs). CM-NP has a diameter of ~ 60 nm and a zeta potential of ~ − 35 mV with a con
Publikováno v:
Molecular Biology Reports. 47:2253-2263
One of the most prevalent malignancies is esophageal squamous cell carcinoma (ESCC), which is associated with high morbidity and mortality. Substance P (SP), as one of the peptides released from sensory nerves, causes the enhancement of cellular exci
Publikováno v:
Preventive Nutrition and Food Science
One of the major challenges for stem cell therapy of ischemic organs is that the transplanted cells are confronted with nutrient deficiency and oxidative stress. Previous studies have indicated that pretreatment of stem cells with cytoprotective phyt
Autor:
Mostafa Karimi Roshan, Arash Soltani, Amir R Afshari, Kolsoum Rezaie Kahkhaie, Anvar Soleimani, Mohammad Soukhtanloo
Publikováno v:
Biochimie. 165:229-234
Epithelial-mesenchymal transition (EMT) is a critical process in the development of many tissues and organs in multicellular organisms that its important role in the pathogenesis of metastasis and tumor cell migration has been firmly established. Dec
Autor:
Majid Ghayour Mobarhan, Farnaz Barneh, Elisa Giovannetti, Majid Khazaei, Milad Hashemzehi, Fereshteh Asgharzadeh, Gordon A. Ferns, Mohieddin Jafari, Reyhaneh Moradi Marjaneh, Seyed Mahdi Hassanian, Amir Avan, Mohammad Reza Ahmadian, Mohammad-Reza Parizadeh, Farzad Rahmani, Mikhail Ryzhikov, Amir R Afshari, Atena Soleimani
Publikováno v:
Cellular Signalling, 85:110069. Elsevier Inc.
Rahmani, F, Hashemzehi, M, Avan, A, Barneh, F, Asgharzadeh, F, Moradi Marjaneh, R, Soleimani, A, Parizadeh, M, Ferns, G A, Ghayour Mobarhan, M, Ryzhikov, M, Afshari, A R, Ahmadian, M R, Giovannetti, E, Jafari, M, Khazaei, M & Hassanian, S M 2021, ' Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway ', Cellular Signalling, vol. 85, 110069 . https://doi.org/10.1016/j.cellsig.2021.110069
Rahmani, F, Hashemzehi, M, Avan, A, Barneh, F, Asgharzadeh, F, Moradi Marjaneh, R, Soleimani, A, Parizadeh, M, Ferns, G A, Ghayour Mobarhan, M, Ryzhikov, M, Afshari, A R, Ahmadian, M R, Giovannetti, E, Jafari, M, Khazaei, M & Hassanian, S M 2021, ' Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway ', Cellular Signalling, vol. 85, 110069 . https://doi.org/10.1016/j.cellsig.2021.110069
Background The therapeutic potency of Rigosertib (RGS) in the treatment of the myelodysplastic syndrome has been investigated previously, but little is known about its mechanisms of action. Methods The present study integrates systems and molecular b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b995e27a8a5df765a3bc452129c8fcc3
https://research.vumc.nl/en/publications/6cfca9ea-00fb-421b-81b4-28fd99d9042d
https://research.vumc.nl/en/publications/6cfca9ea-00fb-421b-81b4-28fd99d9042d
Autor:
Gordon A. Ferns, Amir R Afshari, Fereshteh Asgharzadeh, Farzad Rahmani, Atena Soleimani, Jalal Naghinezhad, Mohammad-Hassan Arjmand, Amir Avan, Maryam Moradi Binabaj, Majid Khazaei, Saeedeh Mehraban, Sayyed Hadi Sayyed‐Hosseinian, Mikhail Ryzhikov, Maryam Fakhraei, Mohammad Reza Parizadeh, Seyed Mahdi Hassanian
Publikováno v:
Journal of Cellular Physiology. 235:1349-1357
Here, we have investigated the therapeutic potency of EW-7197, a transforming growth factor-β type I receptor kinase inhibitor, against postsurgical adhesion band formation. Our results showed that this pharmacological inhibitor prevented the freque
Autor:
Hamid Mollazadeh, Mohammad Jalili-Nik, Hamed Sabri, Amirhossein Sahebkar, Amir R Afshari, Bahram Bibak
Publikováno v:
BioFactors (Oxford, England)REFERENCES. 47(5)
The most widespread and challenging aggressive malignant tumor in the brain is glioblastoma multiforme (GBM). GBM is characterized, in particular, by significant intratumor cell variability, high growth rates, and widespread invasiveness within the s
Autor:
Thomas P. Johnston, Maryam Givari, Mohammad Montazami Sadeghi, Bahram Bibak, Abolfazl Maghrouni, Amirhossein Sahebkar, Hamid Mollazadeh, Amir R Afshari, Mohammad Jalili-Nik
Publikováno v:
International immunopharmacology. 93
Glioblastoma multiforme (GBM), as one of the immunosuppressive and common intrinsic brain tumors in adults, remains an intractable malignancy to manage. Since the standard of care for treatment, which includes surgery and chemoradiation, has not prov