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Autor:
Irum Khan, Nandini Kalakota, Andrei L. Gartel, Olga Frankfurt, Marianna Halasi, Nadim Mahmud, Anand Patel, Yi Hua Chen, Nathan Aardsma, Li Liu, Rachael Schultz, John D. Crispino
Publikováno v:
JCI Insight
Acute myeloid leukemia (AML) patients with NPM1 mutations demonstrate a superior response to standard chemotherapy treatment. Our previous work has shown that these favorable outcomes are linked to the cytoplasmic relocalization and inactivation of F