Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Fang Chen"'
Publikováno v:
Current Stem Cell Research & Therapy. 16:608-621
The prevalence of Heart Failure (HF) has increased over time. Ischemic heart failure accounts for 50% of HF, which results from ischemic coronary heart diseases such as Myocardial Infarction (MI). Conventionally, reduction of cardiac load and revascu
Autor:
Chongguang Yang, Huanming Yang, Xin Meng, Pauline Ogrodzki, Rong Liu, Junhua Li, Stefan Weber, Ashish Koshy, Tao Ma, Ke Liang, Stephen S. Francis, Xavier Anton, Farida Al Hosani, Pengjuan Liu, Wenjun He, Jian Wang, Francis Amirtharaj Selvaraj, Nan Qiao, Xun Xu, Hanif Khalak, Budoor Alqarni, Xin Jin, Sally Mahmoud, Javier Quilez, Walid Abbas Zaher, Mohammed Saifuddin Fasihuddin, Long Lin, Vinay Kusuma, Denghui Liu, Nawal Al Kaabi, Weibin Liu, Zhaorong Yuan, Peng Xiao, Pei Wu, Fang Chen, Xinyu Huang, Siyang Liu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
BASE-Bielefeld Academic Search Engine
Scientific Reports
BASE-Bielefeld Academic Search Engine
To unravel the source of SARS-CoV-2 introduction and the pattern of its spreading and evolution in the United Arab Emirates, we conducted meta-transcriptome sequencing of 1067 nasopharyngeal swab samples collected between May 9th and Jun 29th, 2020 d
Autor:
Shihao Wu, Jing Wu, Liqi Xu, Longbao Lv, Xia Ma, Tian-Lin Cheng, Yingzhou Hu, Xiao Li, Zhi-Fang Chen, Zilong Qiu, Hao Li, Wenchao Wang, Ling Li, Yong Yin, Haisong Jiang, Xintian Hu
Publikováno v:
Neuroscience Bulletin
Whether direct manipulation of Parkinson’s disease (PD) risk genes in the adult monkey brain can elicit a Parkinsonian phenotype remains an unsolved issue. Here, we used an adeno-associated virus serotype 9 (AAV9)-delivered CRISPR/Cas9 system to di
Publikováno v:
Journal of Oncology, Vol 2021 (2021)
Journal of Oncology
Journal of Oncology
The functions of long noncoding RNAs (lncRNAs) have been widely investigated in human cancers, including gastric cancer (GC). The purpose of this study was to elucidate the role of lncRNA HCG11 in GC. In this study, mRNA and protein expressions were
Publikováno v:
Journal of Cellular and Molecular Medicine
Long non‐coding RNA (lncRNA) lnc‐ISG20 has been found aberrantly up‐regulated in the glomerular in the patients with diabetic nephropathy (DN). We aimed to elucidate the function and regulatory mechanism of lncRNA lnc‐ISG20 on DN‐induced re
Autor:
Xiao Han, Tijun Wu, Lin Wang, Fang Chen, Yixue Shao, Jiahui Wang, Yaru Zhang, Xirui Li, Wenyu Dong, Yuqing Guo
Publikováno v:
Journal of Cellular and Molecular Medicine
Chronic ethanol consumption is a well‐established independent risk factor for type 2 diabetes mellitus (T2DM). Recently, increasing studies have confirmed that excessive heavy ethanol exerts direct harmful effect on pancreatic β‐cell mass and fu
Autor:
Guochun Wang, Hanbo Yang, Fang Chen, Xiaoming Shu, Wenli Li, Qingyan Liu, Chuiwen Deng, Xia Liu, Lu Zhang, Xin Lu, Qinglin Peng, Shanshan Li, Lida Chen
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Arthritis Research & Therapy
Arthritis Research & Therapy
Background T cell Ig and ITIM domain (TIGIT)/CD226 pathway has a critical role in regulating T cell responses and has come to the forefront in cancer as a promising immunotherapeutic target. However, its role in autoimmune diseases is just beginning
Autor:
Simon F. Lacey, Caroline Diorio, Edward M. Behrens, David M. Barrett, David L. Porter, Fang Chen, Jenny Bush, Bruce L. Levine, Alena Orlenko, Edward Pequignot, J. Joseph Melenhorst, Jason H. Moore, Natalka Koterba, Pamela A. Shaw, Richard Aplenc, Donglan Zhang, Michele Paessler, David T. Teachey, Vanessa E. Gonzalez, Don L. Siegel, Hamid Bassiri, Stephan A. Grupp, Megan M. Davis, Nuala J. Meyer, Scott L. Weiss, Amanda M. DiNofia, Shannon L. Maude, Carl H. June
Publikováno v:
Blood Adv
Chimeric antigen receptor (CAR) T-cells directed against CD19 have drastically altered outcomes for children with relapsed and refractory acute lymphoblastic leukemia (r/r ALL). Pediatric patients with r/r ALL treated with CAR-T are at increased risk
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Mediators of Inflammation
Mediators of Inflammation
Sepsis remains a major global concern and is associated with high mortality and morbidity despite improvements in its management. Markers currently in use have shortcomings such as a lack of specificity and failures in the early detection of sepsis.
Publikováno v:
Cell Death Differ
Development of renal fibrosis is a hallmark of renal aging and chronic kidney disease of all etiologies and characterized by extensive renal cell injuries and subsequent myofibroblast transdifferentiations (MTDs), which are significantly influenced b