Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Robert A. Anders"'
Autor:
Robert A. Anders, Sepideh Besharati, Xinqun Wu, Franck Housseau, Payam Fathi, Jawara Allen, Laura Jenkins, Shaoguang Wu, David L. Huso, Amanda E. Mackenzie, Ben Park, Cynthia L. Sears, Graeme Milligan, Annemarie Boleij, William Brian Dalton
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, 4
Communications Biology
Communications Biology, 4, 1
Communications Biology, 4
Communications Biology
Communications Biology, 4, 1
G protein-coupled receptor (GPR)35 is highly expressed in the gastro-intestinal tract, predominantly in colon epithelial cells (CEC), and has been associated with inflammatory bowel diseases (IBD), suggesting a role in gastrointestinal inflammation.
Autor:
Margaret A. Tempero, Elizabeth M. Jaffee, Michael Considine, Elana J. Fertig, Beth Onners, Takahiro Tsujikawa, Robert H. Vonderheide, Julie M. Nauroth, Andrew H. Ko, Lisa M. Coussens, Dung T. Le, Dirk G. Brockstedt, Jennifer N. Durham, Daniel A. Laheru, George A. Fisher, Todd S. Crocenzi, Robert A. Anders, Elizabeth A. Sugar, Kim A. Reiss, Ludmila Danilova, Annie A. Wu
Publikováno v:
Clin Cancer Res
Purpose: Two studies in previously treated metastatic pancreatic cancer have been completed combining GVAX pancreas vaccine (GM-CSF–secreting allogeneic pancreatic tumor cells) with cyclophosphamide (Cy) and CRS-207 (live, attenuated Listeria monoc
Autor:
Tricia R. Cottrell, Patrick M. Forde, Elizabeth M. Jaffee, Janis M. Taube, Josephine Feliciano, Mohamad E. Allaf, Julie E. Stein, Evan J. Lipson, Robert A. Anders, Ashley Cimino-Mathews, Mark Yarchoan, Elizabeth D. Thompson, Drew M. Pardoll, Hao Wang, Suzanne L. Topalian
Publikováno v:
Clin Cancer Res
Purpose: Pathologic response assessment of tumor specimens from patients receiving systemic treatment provides an early indication of therapeutic efficacy and predicts long-term survival. Grading systems for pathologic response were first developed f
Autor:
Eric Schiffhauer, Elizabeth M. Jaffee, Quingfeng Zhu, Martin Kräter, Angela Jacobi, Oliver Otto, Alexandra Surcel, Maik Herbig, Katarzyna Plak, Robert A. Anders, Jochen Guck, Pablo A. Iglesias, Douglas N. Robinson, Dustin Thomas, Hoku West-Foyle, Kathleen T. DiNapoli
Publikováno v:
Cancer Research
Metastasis is complex, involving multiple genetic, epigenetic, biochemical, and physical changes in the cancer cell and its microenvironment. Cells with metastatic potential are often characterized by altered cellular contractility and deformability,
Autor:
Gady Cojocaru, Ada J. Tam, Nicolas J. Llosa, Elizabeth D. Thompson, Drew M. Pardoll, Nicholas Siegel, Carol D. Morris, Daniel S. Rhee, Robert A. Anders, John A. Ligon, Teniola Oke, Brian H. Ladle, Aditya Suru, Christine A. Pratilas, Adam S. Levin, Emily Han-Chung Hsiue, Richard L. Blosser, Christian F. Meyer, Franck Housseau, Wei Fu, Woonyoung Choi, Megan H. Fong, David J. McConkey
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundCurrent therapy for osteosarcoma pulmonary metastases (PMs) is ineffective. The mechanisms that prevent successful immunotherapy in osteosarcoma are incompletely understood. We investigated the tumor microenvironment of metastatic osteosarc
Autor:
Teniola Oke, Thomas B. Schaffer, Evan J. Lipson, Dung T. Le, Christian F. Meyer, Lingling Chen, John Mc Mahon Gross, Laurene S. Cheung, Jillian T. Ngo, Nicolas J. Llosa, Janis M. Taube, Holly Kemberling, Karim Boudadi, John-William Sidhom, Robert A. Anders, Drew M. Pardoll, Luis A. Diaz
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Undifferentiated pleomorphic sarcoma (UPS), an aggressive soft-tissue sarcoma of adults, has been characterized by low tumor mutational burden (TMB) and high copy number alterations. Clinical trials of programmed death-1 (PD-1) blockade in UPS have r
Autor:
Qingfeng Zhu, Haidan Guo, Franco Verde, Hao Wang, Patrick M. Forde, Dung T. Le, Sune Justesen, Teniola Oke, Hongni Fan, Prerna Suri, Leslie Cope, Ludmila Danilova, Janis M. Taube, Anas H. Awan, Franck Housseau, Jennifer N. Durham, Hok Yee Chan, Nickolas Papadopoulos, Elizabeth D. Thompson, Bjarne Bartlett, Robert A. Anders, Nicholas Siegel, Victor E. Velculescu, Kellie N. Smith, John-William Sidhom, Laveet K. Aulakh, Kristen A. Marrone, Valsamo Anagnostou, Cynthia L. Sears, Joanne Riemer, Drew M. Pardoll, Luis A. Diaz, Brandon Luber, Ada J. Tam, Bert Vogelstein, Tricia R. Cottrell, Nicolas J. Llosa, Kenneth W. Kinzler, Julie R. Brahmer, William H. Sharfman, Jarushka Naidoo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Background Several predictive biomarkers are currently approved or are under investigation for the selection of patients for checkpoint blockade. Tumor PD-L1 expression is used for stratification of non-small cell lung (NSCLC) patients, with tumor mu
Autor:
Benjamin Green, Aleksandra Ogurtsova, Paul Nghiem, Jennifer H. Yearley, Elizabeth L. Engle, Nirasha Ramchurren, Candice D. Church, Abha Soni, Genevieve J. Kaunitz, Steve Fling, Joel C. Sunshine, Julie E. Stein, Ludmila Danilova, Janis M. Taube, Farah Succaria, Tricia R. Cottrell, Natalie J. Miller, Peter Nguyen, Haiying Xu, Nicolas A. Giraldo, Lisa Lundgren, Robert A. Anders, Mac Cheever, Jonathan D. Cuda, Suzanne L. Topalian, Evan J. Lipson, Sneha Berry
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-11 (2018)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Background We recently reported a 56% objective response rate in patients with advanced Merkel cell carcinoma (MCC) receiving pembrolizumab. However, a biomarker predicting clinical response was not identified. Methods Pretreatment FFPE tumor specime
Autor:
Michael Torbenson, Cynthia D. Guy, Robert A. Anders, Saba Yasir, Sudhakar K. Venkatesh, Zongming Eric Chen, Hee Eun Lee, Tsung Teh Wu
Publikováno v:
Hum Pathol
Summary Cases of new pseudotumors of the liver were collected from multiple medical centers. Four resection and 4 biopsy specimens were collected, including 4 women and 4 men at an average age of 48 ± 15 years (range: 28–73 years). The lesions wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d8aa91da7c2f834a02c59b8cf96047
https://europepmc.org/articles/PMC9469469/
https://europepmc.org/articles/PMC9469469/
Autor:
Aleksandra Popovic, Nina Chu, Minwei Cao, Alexander Hopkins, Elana J. Fertig, Todd D. Armstrong, Robert A. Anders, Bridget P. Keenan, Jacquelyn W. Zimmerman, Elizabeth M. Jaffee
Publikováno v:
Cancer Prev Res (Phila)
Almost all pancreatic ductal adenocarcinomas (PDA) develop following KRAS activation, which triggers epithelial transformation and recruitment of desmoplastic stroma through additional transcriptional and epigenetic regulation, but only a few of thes