Zobrazeno 1 - 10
of 1 677
pro vyhledávání: '"11"'
Autor:
Lisa A. Carey, Patrick L. Leslie, Yvonne L. Chao, Alessandro Porrello, Yi-Hsuan Tsai, Emily B. Harrison, Joel S. Parker, Subrata K. Ghosh, Brian C. Cooley, Chad V. Pecot, Amanda E.D. Van Swearingen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
Lymph node (LN) metastases correspond with a worse prognosis in nearly all cancers, yet the occurrence of cancer spreading from LNs remains controversial. Additionally, the mechanisms explaining how cancers survive and exit LNs are largely unknown. H
Autor:
Eliza Kwiatkowska-Borowczyk, Anna Kowalik, Andrzej Marszałek, Hanna Dams-Kozlowska, Andrzej Mackiewicz, Sebastian Adamczyk, Ewa Leporowska, Anna Lewandowska, Katarzyna Gryska
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154520 (2016)
PLoS ONE
PLoS ONE
The incidence of cancer is constantly increasing. Chemo/radiotherapy is one of major methods of treating cancer. Although adverse chemo/radiotherapy events, such as anemia and neutropenia, can be successfully cured, thrombocytopenia is still problema
Autor:
Alexander Gow, Farhad Ghoddoussi, Shane A. Perrine, Kathleen J. Maheras, Marcello Peppi, Matthew P. Galloway
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
Scientific Reports
Neuronal origins of behavioral disorders have been examined for decades to construct frameworks for understanding psychiatric diseases and developing useful therapeutic strategies with clinical application. Despite abundant anecdotal evidence for whi
Autor:
Francis G. Szele, Susana Frago, Nicholas B. Davies, Mirvat Surakhy, Martin Ducker, Claudia Bühnemann, Matthew P. Crump, Emma J. Carter, Sermet Can, Roman Trikin, A. Bassim Hassan, Jennifer Hughes
Publikováno v:
Scientific Reports
Hughes, J, Surakhy, M, Can, S, Ducker, M, Davies, N, Szele, F, Bühnemann, C, Carter, E, Trikin, R, Crump, M P, Frago, S & Hassan, A B 2019, ' Maternal transmission of an Igf2r domain 11 : IGF2 binding mutant allele (Igf2r I1565A ) results in partial lethality, overgrowth and intestinal adenoma progression ', Scientific Reports, vol. 9, no. 1, 11388 . https://doi.org/10.1038/s41598-019-47827-9
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Hughes, J, Surakhy, M, Can, S, Ducker, M, Davies, N, Szele, F, Bühnemann, C, Carter, E, Trikin, R, Crump, M P, Frago, S & Hassan, A B 2019, ' Maternal transmission of an Igf2r domain 11 : IGF2 binding mutant allele (Igf2r I1565A ) results in partial lethality, overgrowth and intestinal adenoma progression ', Scientific Reports, vol. 9, no. 1, 11388 . https://doi.org/10.1038/s41598-019-47827-9
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
The cation-independent mannose 6-phosphate/insulin-like growth factor-2 receptor (M6P/IGF2R or IGF2R) traffics IGF2 and M6P ligands between pre-lysosomal and extra-cellular compartments. Specific IGF2 and M6P high-affinity binding occurs via domain-1
Autor:
Jitske Jansen, Marinka Bakker-van Bebber, Fieke Mooren, Markus A. Loeven, Brigith Willemsen, Jennifer Eymael, Catherine Meyer-Schwesinger, Bart Smeets, Shagun Sharma, Jack F.M. Wetzels, Henry B.P.M. Dijkman, Johan van der Vlag, Laura Miesen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, 10
Scientific Reports
Scientific Reports, 10
Scientific Reports
Anti-Thy1.1 transgenic mice develop glomerular lesions that mimic collapsing focal segmental glomerulosclerosis (FSGS) in humans with collapse of the glomerular tuft and marked hyperplasia of the parietal epithelial cells (PECs). Immunostaining of ph
Autor:
Kouji Matsushima, Mizuho Hasegawa, Eri Nakamura, Kazutoshi Shibuya, Takashi Nishina, Daisuke Ohshima, Wakami Takeda, Norihiro Tada, Chiharu Nishiyama, Tetuo Mikami, Mizuho Nakayama, Shigeyuki Shichino, Hiroyasu Nakano, Mika Kawauchi, Masato Ohtsuka, Hideo Yagita, Naohiro Inohara, Satomi Adachi-Akahane, Masanobu Oshima, Soh Yamazaki, Yuko Kojima, Yutaka Deguchi, Satoshi Ueha
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Interleukin (IL)-11 is a member of the IL-6 family of cytokines and is involved in multiple cellular responses, including tumor development. However, the origin and functions of IL-11-producing (IL-11+) cells are not fully understood. To characterize
Autor:
Filiz T. Korkmaz, Joseph P. Mizgerd, Matthew R. Jones, Katrina E. Traber, Lee J. Quinton, Ernest L. Dimbo, Elise M. Symer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0221029 (2019)
PLoS ONE, Vol 14, Iss 8, p e0221029 (2019)
Interleukin-11 (IL-11) is an interleukin-6 (IL-6) family cytokine shown to play a protective role in acute inflammatory settings including systemic infection. In this study we addressed the role of IL-11 in acute bacterial pneumonia using a mouse mod
Autor:
Jeroen H. F. de Baaij, Steef Kurstjens, Mohamed Kebieche, Hacene Bouras, Joost G. J. Hoenderop, Caro Overmars-Bos, René J. M. Bindels
Publikováno v:
Scientific Reports, 9
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Approximately 30% of patients with type 2 diabetes mellitus (T2D) have hypomagnesemia (blood magnesium (Mg2+) concentration 2+ levels. To investigate how T2D and metformin affect Mg2+ homeostasis db/m and db/db mice were treated with metformin or pla
Autor:
Nathaniel Rothman, Yolanda Benavente, Paul Brennan, Qing Lan, Pierluigi Cocco, Simon Crouch, Anneclaire J. De Roos, Josh Wright, Christine F. Skibola, Mark P. Purdue, Elisabete Weiderpass, James R. Cerhan, Randy D. Gascoyne, Maria Grazia Ennas, Kari E. North, Zhaoming Wang, Jinyan Huang, Julie M. Cunningham, Alain Monnereau, Peter Kraft, Patricia Hartge, Edward Giovannucci, Karen Curtin, Giovanna Masala, Jacqueline Clavel, Neil E. Kay, Jacques Riby, María Dolores Chirlaque, John J. Spinelli, Delphine Casabonne, Jenny Turner, Lucia Conde, Lesley F. Tinker, Martha Glenn, Sara S. Strom, Donna K. Arnett, Rebecca Montalvan, Ju-Hyun Park, Melissa C. Southey, Ann Maria, Karin E. Smedby, Lindsay M. Morton, Marc Maynadié, Laurie Burdett, Amy Hutchinson, Bengt Glimelius, W. Ryan Diver, Elio Riboli, Sonja I. Berndt, Lisa A. Cannon-Albright, Kimberly A. Bertrand, Aaron D. Norman, Sara J. Achenbach, Celine M. Vachon, Angela Cox, Xifeng Wu, Theodore R. Holford, Neil E. Caporaso, Joseph F. Fraumeni, Roel Vermeulen, Rudolph Kaaks, Mads Melbye, Joseph Vijai, Kari G. Chaffee, Lauren R. Teras, Rebecca D. Jackson, Lenka Foretova, J. Brice Weinberg, Paige M. Bracci, Sophia S. Wang, Demetrius Albanes, Stephen J. Chanock, Wendy Cozen, Mark Liebow, Anne J. Novak, Hans-Olov Adami, George J. Weiner, Angela Brooks-Wilson, Kenneth Offit, Anne Kricker, Claire M. Vajdic, James McKay, Ellen T. Chang, Baoshan Ma, Cristine Allmer, Susan L. Slager, Brian K. Link, Elizabeth A. Holly, Anthony Staines, Liming Liang, Jarmo Virtamo, Timothy G. Call, Nicola J. Camp, Ruth C. Travis, Alexandra Nieters, Degui Zhi, Brenda M. Birmann, Tait D. Shanafelt, Rachel S. Kelly, Graham G. Giles, Nilanjan Chatterjee, John A. Snowden, Yuanqing Ye, Núria Sala, Tongzhang Zheng, Paolo Boffetta, Lynn R. Goldin, Danylo J. Villano, Jose F. Leis, Paolo Vineis, Lucia Miligi, Jian Gu, Justin M. Leach, Silvia de Sanjosé, Richard K. Severson, Yawei Zhang, Henrik Hjalgrim, Roger L. Milne, Charles E. Lawrence, Meredith Yeager, Moara Machado, Nikolaus Becker, Joseph M. Connors, Anne Zeleniuch-Jacquotte, Giovanni Maria Ferri, Stephanie J. Weinstein
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Communications
Nature Communications, Nature Publishing Group, 2016, 7, 〈https://www.nature.com/articles/ncomms10933〉. 〈10.1038/ncomms10933〉
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications, Nature Publishing Group, 2016, 7, ⟨10.1038/ncomms10933⟩
Nature Communications [E], 7. Nature Publishing Group
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Communications
Nature Communications, Nature Publishing Group, 2016, 7, 〈https://www.nature.com/articles/ncomms10933〉. 〈10.1038/ncomms10933〉
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications, Nature Publishing Group, 2016, 7, ⟨10.1038/ncomms10933⟩
Nature Communications [E], 7. Nature Publishing Group
Chronic lymphocytic leukemia (CLL) is a common lymphoid malignancy with strong heritability. To further understand the genetic susceptibility for CLL and identify common loci associated with risk, we conducted a meta-analysis of four genome-wide asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f977c49c00f0687004f3a881710fa78
https://dspace.library.uu.nl/handle/1874/345512
https://dspace.library.uu.nl/handle/1874/345512
Autor:
Jennifer M. Carr, Edith A. Perez, Julia E. Crook, Bianca C. Axenfeld, Panos Z. Anastasiadis, Daniel J. Serie, Alvaro Moreno-Aspitia, Brian M. Necela, Jennifer M. Kachergus, Ryan W. Feathers, Pooja Advani, E. Aubrey Thompson, Nadine Norton, Xochiquetzal J. Geiger
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 4, p e0153411 (2016)
PLoS ONE, Vol 11, Iss 4, p e0153411 (2016)
Background Invasive lobular carcinoma (ILC) comprises approximately ~10–20% of breast cancers. In general, multifocal/multicentric (MF/MC) breast cancer has been associated with an increased rate of regional lymph node metastases. Tumor heterogenei