Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Normanno N"'
Autor:
Cardone C., Blauensteiner B., Moreno-Viedma V., Martini G., Simeon V., Vitiello P. P., Ciardiello D., Belli V., Matrone N., Troiani T., Morgillo F., Zito Marino F., Dentice M., Nappi A., Boccaccino A., Antoniotti C., Cremolini C., Pietrantonio F., Prager G. W., Normanno N., Maiello E., Argiles G., Elez E., Signoriello G., Franco R., Falcone A., Tabernero J., Sibilia M., Ciardiello F., Martinelli E., ZITO MARINO, Federica
Background RAS mutations are the only validated biomarkers in metastatic colorectal cancer (mCRC) for anti-epidermal growth factor receptor (EGFR) therapy. Limited clinical information is available on AXL expression, marker of epithelial to mesenchym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4937b3b9337afc85a90006c6268b2a74
https://hdl.handle.net/11588/920571
https://hdl.handle.net/11588/920571
Autor:
Nicla La Verde, Fiamma Buttitta, Maria Angela Bella, Massimo Barberis, Ettore Capoluongo, Chiara Trevisiol, Pierosandro Tagliaferri, Enrico Ricevuto, Nicola Normanno, Nicoletta Colombo, Matilde Pensabene, Antonio Russo, Sandro Pignata, Anna Sapino, Domenica Lorusso, Liliana Varesco, Maurizio Genuardi, Lorena Incorvaia, Massimo Gion, Valentina Guarneri, Laura Cortesi, Pierfrancesco Tassone, Paolo Radice, Mauro Truini, Paolo Marchetti, Stefania Gori, Antonio Marchetti, Barbara Pasini, Paola Carrera
The current availability of new Poly(ADP-ribose) Polymerase (PARP)-inhibitors for the treatment of ovarian cancer patients independently of the presence of a BRCA pathogenic variant, together with the validation of somatic test for the analysis of BR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942108ee20348ca4ec8b28d92ca4333a
http://hdl.handle.net/10447/437173
http://hdl.handle.net/10447/437173
Autor:
Ettore Capoluongo, Sandro Pignata, Paola Carrera, Enrico Ricevuto, Maurizio Genuardi, Paolo Radice, Antonio Russo, Nicoletta Colombo, Carmine Pinto, Stefania Gori, Barbara Pasini, Paolo Marchetti, Nicola Normanno, Valentina Guarneri, Laura Cortesi, Antonio Marchetti, Mauro Truini, Maria Angela Bella, Pierosandro Tagliaferri, Pierfrancesco Tassone, Gaetano De Rosa, Francesca Fenizia, Claudio Clemente, Liliana Varesco
In the last 20 years, following the identification of the BRCA1 and BRCA2 genes (hereinafter referred to as the BRCA genes), preventive pathways have been developed for the identification and clinical management of individuals at high risk of develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb9b4ad22ad35cde975131fad7a5a30
http://hdl.handle.net/11577/3362422
http://hdl.handle.net/11577/3362422
Autor:
Francesco Izzo, Anna Maria Trotta, Vittorio Albino, Lucrezia Silvestro, Antonio Avallone, Raffaele Palaia, Gerardo Botti, Monica Capozzi, Paolo Chiodini, Rossana Casaretti, Carmine Picone, Stefania Scala, Nicola Normanno, Mario Tamburini, Andrea Belli, Crescenzo D'Alterio, Anna Maria Rachiglio, Massimiliano Di Marzo, Guglielmo Nasti, Paolo Delrio, Cristin Roma, Anna Nappi, Carmela Romano, Antonella Petrillo, Antonino Cassata, Gianfranco De Feo, Alessandro Ottaiano, Salvatore Tafuto, Maria Napolitano, Alfonso Amore, Alfonso De Stefano, Ugo Pace, Luigi Portella
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
BMC Cancer
BMC Cancer
Background Combination of chemotherapies (fluoropirimidines, oxaliplatin and irinotecan) with biologic drugs (bevacizumab, panitumumab, cetuximab) have improved clinical responses and survival of metastatic colorectal cancer (mCRC). However, patients
Autor:
Marion Vandromme, Jean Philippe Spano, Olivier Cussenot, Chloé Rideau, Carole Corsini, Isabelle Treilleux, Michèle Vintraud, Ignace Vergote, Yves-Jean Bignon, Kevin S. Hughes, Bernard Baertschi, Eitan Friedman, Daniel Zarca, Marie Duboys de Labarre, Pascal Pujol, Jean Marc Rey, Joseph Gligorov, Ettore D. Capoluongo, Clarisse Duriez, Marion Imbert-Bouteille, Yann Neuzillet, Jean-Louis Mandel, Isabelle Ray-Coquard, Laurence Gladieff, Jose E. Alés Martínez, Frédérique Penault-Llorca, Karim Fizazi, Pierre Jean Lamy, Julie A. Vendrell, Pascal Hammel, Thibault De La Motte Rouge, Jesus Garcia Foncillas, Diether Lambrechts, Tatiana Kogut-Kubiak, Karen Baudry, William Jacot, William D. Foulkes, Frédéric Thomas, Sophie Nambot, Massimo Barberis, Michèle Anahory, Matti Aapro, Xavier Rebillard, Josep M. Piulats, Florence Duchamp, Steven A. Narod, Sylviane Olschwang, Banu Arun, Marc Bollet, Philp Beer, Clare Turnbull, Helen Hanson, Nicola Normanno, Virginie Galibert
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
European Journal of Cancer
European Journal of Cancer, 2021, 146, pp.30-47. ⟨10.1016/j.ejca.2020.12.023⟩
European Journal of Cancer, Elsevier, 2021, 146, pp.30-47. ⟨10.1016/j.ejca.2020.12.023⟩
Universidad de Barcelona
European Journal of Cancer
European Journal of Cancer, 2021, 146, pp.30-47. ⟨10.1016/j.ejca.2020.12.023⟩
European Journal of Cancer, Elsevier, 2021, 146, pp.30-47. ⟨10.1016/j.ejca.2020.12.023⟩
BRCA1 and BRCA2 gene pathogenic variants account for most hereditary breast cancer and are increasingly used to determine eligibility for PARP inhibitor (PARPi) therapy of BRCA-related cancer. Because issues of BRCA testing in clinical practice now o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68784e83fff96e28dfb34c7477a991a
http://hdl.handle.net/2445/176353
http://hdl.handle.net/2445/176353
Autor:
Teresa Troiani, Giulia Martini, F. De Vita, Claudia Cardone, Tiziana Latiano, Fortunato Ciardiello, Evaristo Maiello, Nicola Normanno, Erika Martinelli, Anna Maria Rachiglio, Pietro Paolo Vitiello, Davide Ciardiello
Epidermal growth factor receptor (EGFR) inhibitors are valuable therapeutics in metastatic colorectal cancer (mCRC). Anti-EGFR monoclonal antibodies (MoAbs), such as cetuximab or panitumumab, in combination with chemotherapy are effective treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc1e2145074e4fd31c7a3f556eb19ea
http://hdl.handle.net/11591/427752
http://hdl.handle.net/11591/427752
Autor:
Antonio Rossi, Francesco Perrone, Filippo de Marinis, Fortunato Ciardiello, Agnese Montanino, Cesare Gridelli, Floriana Morgillo, Nicola Normanno, Ciro Gallo, Gennaro Daniele, Lucio Crinò, Maria Carmela Piccirillo, Alessandro Morabito
Publikováno v:
Clinical Lung Cancer. 17:461-465
BACKGROUND: About 20% of advanced non-small-cell lung cancer (NSCLC) cases harbor somatic mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) gene. In these patients, the standard first-line treatments are the EGFR-
Autor:
Alessia Iannaccone, Daniela Frezzetti, Anna Maria Rachiglio, Marianeve Carotenuto, Evaristo Maiello, Antonella De Luca, Cristin Roma, Matilde Lambiase, Francesca Fenizia, Nicola Normanno, Fortunato Ciardiello, E. Martinelli, Claudia Cardone
Publikováno v:
Cancers, Vol 11, Iss 6, p 859 (2019)
Cancers
Volume 11
Issue 6
Cancers
Volume 11
Issue 6
Previous findings suggest that metastatic colorectal carcinoma (mCRC) patients with KRAS/NRAS/BRAF/PIK3CA wild-type (quadruple-wt) tumors are highly sensitive to anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (MoAbs). However, add
Autor:
Giovanni Scambia, Cosimo Sacco, Giorgio Valabrega, Maria Carmela Piccirillo, Antonella Savarese, Pierosandro Tagliaferri, Rossella Lauria, Francesco Perrone, Ugo De Giorgi, Sabrina Chiara Cecere, Marilena Di Napoli, Saverio Cinieri, Gabriella Ferrandina, Ciro Gallo, Giulia Amadio, Maria Ornella Nicoletto, Vanda Salutari, Nicola Normanno, Sandro Pignata, Domenica Lorusso, Simona Losito, Giuseppa Maltese, Gennaro Daniele, Anna Maria Mosconi, Claudia Omarini, Alessandra Sacco, Carmela Pisano, Stefano Greggi, Simona Signoriello, Barbara Kopf, Francesco Raspagliesi
Publikováno v:
Gynecologic oncology. 153(3)
Background Cervical cancer cells often express Epidermal Growth Factor Receptor (EGFR). Cetuximab (CET), an anti-EGFR antibody, can be safely combined with carboplatin (C) and paclitaxel (P), a standard treatment for advanced/recurrent cervical cance
Autor:
Emanuela Rossi, Francesca Di Rella, Carlo Putzu, Francesco Perrone, Rossella Lauria, Lucia Del Mastro, Gennaro Daniele, Vittorio Simeon, Vincenza Tinessa, Ermelinda De Maio, Sabino De Placido, G. Landi, Sandro Barni, Francesco Nuzzo, Saverio Cinieri, Giovanni Iodice, Andrea de Matteis, Nicola Normanno, A. Fabbri, Carmen Pacilio, Laura Arenare, Maria Carmela Piccirillo, Toni Ibrahim, Valeria Forestieri, Angela Stefania Ribecco, Adriano Gravina, Ciro Gallo, Stefania Gori, Anna Maria Mosconi, Ferdinando Riccardi, Michele Orditura, Michelino De Laurentiis
Publikováno v:
European journal of cancer (Oxford, England : 1990). 118
Aim The aim of the study is to analyse whether letrozole (L) and zoledronic acid plus L (ZL) are more effective than tamoxifen (T) as adjuvant endocrine treatment of premenopausal patients with breast cancer with hormone receptor–positive (HR+) tum