Zobrazeno 1 - 10
of 140
pro vyhledávání: '"11"'
Publikováno v:
Fish & Shellfish Immunology. 99:44-51
Interleukin 11 (IL-11) is a secretory cytokine with pleotropic properties, including anti-inflammatory and anti-apoptotic functions. This study aimed to functionally characterize a teleostean IL-11a ortholog from redlip mullet (LhIL-11a) through bioi
Autor:
Irvin Jose, Ashley Mansell, Liana Mackiewicz, Boris Reljic, Richard S. Hotchkiss, Hamsa Puthalakath, Joseph Menassa, Christina Nedeva, Pierre Faou, Marc Pellegrini, Marcel Doerflinger
Publikováno v:
The FEBS Journal. 288:1809-1821
Sepsis remains to be a major contributor to mortality in ICUs, and immune suppression caused by immune cell apoptosis determines the overall patient survival. However, diagnosis of sepsis-induced lymphopenia remains problematic with no accurate progn
Autor:
Matijs van Meurs, Adnan Aslan, Fransien van Dijk, Rik Mencke, Daniela Jou-Valencia, Peter Heeringa, Joost G. J. Hoenderop, Jan-Luuk Hillebrands, Jan G. Zijlstra, Grietje Molema, Eliane R. Popa, Jill Moser
Publikováno v:
Critical Care Medicine
Critical Care Medicine, 46(12), E1196-E1203. LIPPINCOTT WILLIAMS & WILKINS
Critical Care Medicine, 46, 12, pp. E1196-E1203
Critical Care Medicine, 46, E1196-E1203
Critical Care Medicine, 46(12), E1196-E1203. LIPPINCOTT WILLIAMS & WILKINS
Critical Care Medicine, 46, 12, pp. E1196-E1203
Critical Care Medicine, 46, E1196-E1203
Supplemental Digital Content is available in the text.
Objectives: To determine the applicability of recombinant Klotho to prevent inflammation and organ injury in sepsis in man and mice. Design: Prospective, clinical laboratory study using “w
Objectives: To determine the applicability of recombinant Klotho to prevent inflammation and organ injury in sepsis in man and mice. Design: Prospective, clinical laboratory study using “w
Autor:
Alexander Brill, Steven G. Thomas, Joshua H. Bourne, Malou Zuidscherwoude, Joana Campos, Steve P. Watson, Evelyn Garlick, Martina Colicchia, Lauren V. Terry, Jagadeesh Bayry, Ying Di, Nonantzin Beristain-Covarrubias, Julie Rayes
Publikováno v:
Frontiers in Immunology, 12
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2021, 12, pp.693974. ⟨10.3389/fimmu.2021.693974⟩
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, 2021, 12, pp.693974. ⟨10.3389/fimmu.2021.693974⟩
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2021, 12, pp.693974. ⟨10.3389/fimmu.2021.693974⟩
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, 2021, 12, pp.693974. ⟨10.3389/fimmu.2021.693974⟩
Contains fulltext : 239027.pdf (Publisher’s version ) (Open Access) Platelets play a key role in the development, progression and resolution of the inflammatory response during sterile inflammation and infection, although the mechanism is not well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99325c1544dce87442c95388ab82941
http://hdl.handle.net/2066/239027
http://hdl.handle.net/2066/239027
Publikováno v:
Redox Biology, Vol 12, Iss, Pp 438-455 (2017)
Redox Biology
Redox Biology
Resolvins are a novel class of lipid mediators that play an important role in the resolution of inflammation, although the underlying mechanisms are not very clear. To explore the anti-inflammatory mechanisms of resolvins, we have studied the effects
Autor:
Danijela Markovic, Pei F. Lai, Mark R. Johnson, Angela Yulia, Ektoras X. Georgiou, Bronwen R. Herbert, Natasha Singh
Publikováno v:
Biology of reproduction. 101(4)
Although progesterone (P4) supplementation is the most widely used therapy for the prevention of preterm labor (PTL), reports of its clinical efficacy have been conflicting. We have previously shown that the anti-inflammatory effects of P4 can be enh
Publikováno v:
Biology of reproduction. 100(2)
Aims: Globally, sepsis is a major cause of mortality through the combination of cardiovascular collapse and multiorgan dysfunction. Pregnancy appears to increase the risk of death in sepsis, but the exact reason for the greater severity is unclear. I
The response of the innate immune and cardiovascular systems to LPS in pregnant and nonpregnant mice
Autor:
Masao Takata, Mark R. Johnson, Lydia F Edey, James Leiper, Fabiana Gordon, Julia Zöllner, Kieran P. O'Dea, Laura G. Howe
Sepsis is the leading cause of direct maternal mortality, but there are no data directly comparing the response to sepsis in pregnant and nonpregnant (NP) individuals. This study uses a mouse model of sepsis to test the hypothesis that the cardiovasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c96f296b3b076edbb32772eb9a3a4b
http://hdl.handle.net/10044/1/52959
http://hdl.handle.net/10044/1/52959
Autor:
Yuanrong Dai, Xuejun Qin, Songmin Ying, Jiesen Zhou, Fang Liu, Zhihua Chen, Wen Li, Huahao Shen, Yuehai Ke, Zhangwei Qiu
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177334 (2017)
PLoS ONE
PLoS ONE
Shp2 played an important role in cigarette-smoke-mediated inflammation, surfactant homeostasis and asthmatic airway remodeling. However, whether shp2 plays a key role in epithelium-associated allergic reaction is still unknown. In this study, LPS and
Autor:
Lydia F Edey, David A. MacIntyre, Kieran P. O'Dea, Bronwen R. Herbert, Mark R. Johnson, Philip R. Bennett, Renyi Hua, Simon N. Waddington, Masao Takata
Inflammation plays a key role in human term and preterm labor (PTL). Intrauterine LPS has been widely used to model inflammation-induced complications of pregnancy, including PTL. It has been shown to induce an intense myometrial inflammatory cell in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a80e0ff4891a2feb175c5bc5d9b2a92
http://hdl.handle.net/10044/1/43812
http://hdl.handle.net/10044/1/43812