Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Yue Zhou"'
Publikováno v:
Brain Research Bulletin. 163:40-48
Melatonin (Mel) has neuroprotective effects; however, its roles in hypoxic-ischemic brain damage (HIBD) and the underlying mechanisms remain unknown. We aimed to explore its roles and mechanisms in a HIBD rat model. We found that exogenous Mel treatm
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 47:1049-1057
Cisplatin (DDP) resistance limits its efficacy for retinoblastoma (Rb). Hypoxia-inducible factor-1α (HIF-1α) has been shown to contribute to chemotherapy resistance in tumours under hypoxic conditions. This study was designed to explore the role an
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
Eccentric exercise training accompanied by a low-fat diet can prevent insulin resistance (IR) and is currently an effective method for the treatment of IR induced by high-fat diet (HFD)-associated obesity. However, the molecular mechanisms underlying
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
The infiltration and deposition of cholesterol in the arterial wall play an important role in the initiation and development of atherosclerosis. Smooth muscle cells (SMCs) are the major cell type in the intima. Upon exposure to cholesterol, SMCs may
Autor:
Bei-Bei Zhao, Li Zhang, Jing Chen, Lei Hu, Fan Yang, Yue Zhou, Xiaofan Zhu, Wei Zhao, Xin-Mei Yang
Publikováno v:
Drug Design, Development and Therapy
Li Zhang,1,* Xin-Mei Yang,2,* Jing Chen,3 Lei Hu,4 Fan Yang,5 Yue Zhou,5 Bei-Bei Zhao,1 Wei Zhao,2,5,* Xiao-Fan Zhu1,* 1Department of Pediatric, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, In
Autor:
Samantha Shi Min Ling, Yan Xia Ng, Tuck Wah Ng, Qingsong Lin, Jenny P.C. Chong, Teck Kwang Lim, Shera Lilyanna, Oi Wah Liew, Enoch Ming Wei Ng, Peipei Wang, Eliot R. Y. Leong, Qifeng Lin, A. Mark Richards, Yue Zhou, Angeline E. S. Lim
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
High quality, well-validated antibodies are needed to mitigate irreproducibility and clarify conflicting data in science. We describe an epitope-directed monoclonal antibody (mAb) production method that addresses issues of antibody quality, validatio
Autor:
Yongjun Wang, Honghua Song, Hao Liang, Ziwen Zhu, Nan Du, Yuming Hu, Yue Zhou, Tiancheng Song, Xiaojun Chen, Yingjie Wang
Publikováno v:
Journal of Molecular Histology. 50:355-367
Based on deep RNA sequencing of distal segments of lesioned sciatic nerves, a huge number of differentially expression genes (DEGs) were thus obtained and functionally analyzed. The inflammatory response was denoted as one of most significant biologi
Publikováno v:
Neuroscience. 408:349-360
Oxysterol derived from cholesterol metabolism is involved in the inflammatory activation, and consequently in development of major chronic diseases. Multiple cytokines have been found to induce the expression of cholesterol metabolism-related enzymes
Autor:
Huaxin Liang, Jie Wang, Xu Huijing, Lei Zhang, Yan Li, Wei Liu, Yingya Li, Miao Li, Yue Zhou, Meiyan Sun
Publikováno v:
Cancer Management and Research
Jie Wang,1 Huaxin Liang,2 Meiyan Sun,3 Lei Zhang,3 Huijing Xu,3 Wei Liu,3 Yan Li,3 Yue Zhou,4 Yingya Li,5 Miao Li2 1Department of Neurology, The China-Japan Union Hospital of Jilin University, Changchun 130033, China; 2Department of Neurosurgery, The
Autor:
Jifeng Wang, Hongyang Liu, Yifa Zhou, Junjie Hou, Zhangjing Niu, Yue Zhou, Wen Zhong, Fuquan Yang, Miaomiao Xue, Zonghong Li, Tao Xu
Publikováno v:
Molecular & Cellular Proteomics. 17:2119-2131
Chronic hyperlipidemia causes the dysfunction of pancreatic β-cells, such as apoptosis and impaired insulin secretion, which are aggravated in the presence of hyperglycemia. The underlying mechanisms, such as endoplasmic reticulum (ER) stress, oxida