Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Allison Berger"'
Autor:
Kathryn A. Rizzo, Steven Grant, Sri Lakshmi Chalasani, Lawrence F. Povirk, Liang Zhou, Yun Dai, Mohamed Rahmani, Allison Berger, Andrea Ferreira-Gonzalez, Lihong Li, Hui Lin, Catherine I. Dumur, Yun Leng, Shuang Chen, Maciej Kmieciak, Yu Zhang
Publikováno v:
Blood. 127:2219-2230
Two classes of novel agents, NEDD8-activating enzyme (NAE) and histone deacetylase (HDAC) inhibitors, have shown single-agent activity in acute myelogenous leukemia (AML)/myelodysplastic syndrome (MDS). Here we examined mechanisms underlying interact
Autor:
Dennis Huszar, Allison Berger, Alejandro Gomez-Pinillos, Mi-Sook Kim, Amitkumar Mehta, Igor Proscurshim, Chirag Patel, Paolo Caimi, Bingxia Wang, Sarit Assouline, Sharon Friedlander
Publikováno v:
Blood. 134:1593-1593
Background TAK-981 is a first-in-class, small molecule inhibitor of SUMOylation, a reversible post-translational modification that regulates protein function by covalent attachment of small ubiquitin-like modifier (SUMO) proteins to a protein substra
Autor:
Isere Kuiatse, Hua Wang, Nibedita Chattopadhyay, Robert Z. Orlowski, Saurabh Menon, Judy Qiuju Shi, Junling Zhuang, Hans C. Lee, Vaishali Shinde, Allison Berger, Marc L. Hyer, Anna Kreshock, Stephen Tirrell, Sakeena Syed, Jie Yu, Richard J. Jones, Fazal Shirazi
Publikováno v:
Blood. 128:3296-3296
Background: The ubiquitin-proteasome system (UPS) has been validated as a target in multiple myeloma (MM) through the success of proteasome inhibitors such as bortezomib, but drug resistance is an emerging challenge. Targeting some of the upstream co