Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Matteo Pirro"'
Publikováno v:
Seminars in Cancer Biology. 69:337-348
Despite considerable advances in the application of liposomal drug delivery systems in cancer treatment, the clinical application of liposomal formulations has been limited by many factors. It seems that there is a wide gap between results of experim
Autor:
Paolo Puccetti, Rita Chiari, Francesca Fallarino, Vanessa Bianconi, Biagio Ricciuti, Giulia Costanza Leonardi, Amirhossein Sahebkar, Matteo Pirro, Sara Baglivo
Publikováno v:
Pharmacology & Therapeutics. 196:105-116
Immunotherapy through immune checkpoint blockers (ICBs) is quickly transforming cancer treatment by improving patients' outcomes. However, innate and acquired resistance to ICBs remain a major challenge in clinical settings. Indoleamine 2,3-dioxygena
Publikováno v:
International Journal of Cancer. 143:2105-2115
Cytokine members of the IL-12 family have attracted enormous attention in the last few years, with IL-35 being the one of the most attractive-suppressive cytokine. IL-35 is an important mediator of regulatory T cell function. Regulatory T cells play
Publikováno v:
Current Opinion in Hematology. 25:44-51
Monocyte chemoattractant protein (MCP)-1, a chemokine regulating monocyte chemotaxis and T-lymphocyte differentiation by binding to the CC chemokine receptor 2 (CCR2), plays a crucial role in the pathogenesis of inflammatory diseases, atherosclerosis
Publikováno v:
BioFactors. 43:331-346
Curcumin, the bioactive polyphenolic ingredient of turmeric, has been extensively studied for its effects on human papilloma virus (HPV) infection as well as primary and malignant squamous cervical cancers. HPV infections, especially those related to
Autor:
Mahmoud Reza Jaafari, Amirhossein Sahebkar, Matteo Pirro, Mahdi Hatamipour, Seyed Mohammad Gheibi Hayat, Vanessa Bianconi
Publikováno v:
Cellular oncology (Dordrecht). 43(1)
CD47 is a widely expressed cellular receptor well known for its immunoregulatory functions. By interacting with its ligands, including thrombospondin-1 (TSP-1), signal regulatory protein α (SIRPα), integrins, and SH2-domain bearing protein tyrosine
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 120, Iss, Pp-(2019)
Stem cells have a therapeutic potential in various medical conditions. In cases without sufficient response to conventional drug treatments, stem cells represent a next generation therapeutic strategy in cardiovascular diseases. Cardiac stem cells (C
Autor:
Marco Avila-Rodriguez, Amirhossein Sahebkar, George E. Barreto, Tannaz Jamialahmadi, Mohammad Mohajeri, Vanessa Bianconi, Matteo Pirro
Publikováno v:
Pharmacological research. 156
Curcumin (Cur) is an active derivative extracted from turmeric which exerts a wide range of interactions with biomolecules through complex signaling pathways. Cur has been extensively shown to possess potential antitumor properties. In addition, ther
Autor:
Andrea De Giglio, Giuseppe Lamberti, Biagio Ricciuti, Amirhossein Sahebkar, Rita Chiari, Carlo Genova, Elisa Andrini, Vanessa Bianconi, Matteo Pirro
Publikováno v:
Seminars in cancer biology. 69
With 9.6 million deaths in 2018, cancer represents one of the most common causes of death, both in men and women. Despite recent advances in the understanding of molecular mechanisms involved in cancer development and progression, treatment options a
Publikováno v:
Cancer letters. 459
Tumor tolerance is known as a condition of systemic immune unresponsiveness or immunosuppression against cancers, in which malignant cells escape from the immune surveillance. Among the elements of immune tolerance orchestra, the CD4+CD25 + forkhead