Zobrazeno 1 - 10
of 384
pro vyhledávání: '"72"'
Publikováno v:
Journal of infection in developing countries. 13(11)
Introduction: This research aimed to determine the association of the combination of H. pylori infection and TP53 codon 72 polymorphism with non-cardia gastric cancer (GC) in Vietnam. Methodology: A total of 164 patients with non-cardia GC and 164 pa
Autor:
Linyuan Qin, Xiaoqiang Qiu, Xiangyuan Yu, Hongping Yu, Songqing He, Bo Tang, Chunhua Bei, Yingchun Liu, Moqin Qiu, Xiaoyun Zeng
Publikováno v:
Tumor Biology. 37:3863-3870
The p53 tumor suppressor and its negative regulator, murine double minute 2 (MDM2), play critical roles in carcinogenesis. P53 codon 72 and MDM2 309T>G polymorphisms could influence p53 and MDM2 function, respectively, and might affect cancer suscept
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Journal of Diabetes Research
Journal of Diabetes Research
We aimed to investigate whether swimming exercise could improve insulin resistance (IR) by regulating tripartite motif family protein 72 (TRIM72) expression and AKT signal pathway in rats fed with high-fat diet. Five-week-old rats were classified int
Autor:
Margarita Gerou, Benjamin A. Hall, Scott P. Allen, Kathrin Meyer, Pamela J. Shaw, Ryan Woof, Jessica Allsop, Stephen J. Kolb
Publikováno v:
Neurobiology of Aging
Highlights • Aging affects the metabolic profile of fibroblasts derived from ALS cases • Increased NADH metabolism with age is observed in the presence of a specific set of catabolic energy substrates in healthy individuals • Reduced NADH metab
Autor:
Yu Cheng, Brenda C. M. de Winter, Juan Chen, Hong-Qiang Qiu, Rui-Xiang Xie, Hui Wu, Zheng Jiao, Qiu-Ling Zhao, Jing Huang, Lin Yang, Chang-Cheng Sheng
Publikováno v:
Cancer Chemotherapy & Pharmacology, 85(5), 881-897. Springer-Verlag
High-dose methotrexate (HD-MTX) is widely used in the treatment of non-Hodgkin lymphoma (NHL), but the pharmacokinetic properties of HD-MTX in Chinese adult patients with NHL have not yet been established through an approach that integrates genetic c
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 315:H1287-H1292
Abnormal pulmonary vascular development is a critical factor in the pathogenesis of bronchopulmonary dysplasia (BPD). Despite the well-established sex-specific differences in the incidence of BPD, the molecular mechanism(s) behind these are not compl
Autor:
Christopher P. Hedges, Bhoopika Shetty, Troy L. Merry, Anthony J. R. Hickey, Peter R. Shepherd, Toan Pham, Stewart W. C. Masson
Publikováno v:
Bioscience Reports
Genetic inhibition of the p110α isoform of phosphatidylinositol-3-kinase (PI3K) can increase murine lifespan, enhance mitochondrial function and alter tissue-specific oxidative balance. Here, we investigated whether pharmacological inhibition of the
Autor:
Ewa Śliwicka, Tomasz Cisoń, Łucja Pilaczyńska-Szcześniak, Anna Straburzyńska-Lupa, Andrzej Ziemba
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
In recent years, there has been increasing interest in the homeostatic response to extreme exercises, especially in the integrated function of muscle and bone. The aim of this study was to evaluate the effects of a marathon race on selected myokines
Publikováno v:
Experimental neurology. 331
Background and purpose The present study was designed to investigate the potential role and the mechanism of equilibrative nucleoside transporter 1 (ENT1) on neuronal apoptosis and neurological deficits after middle cerebral artery occlusion (MCAO) i
Autor:
Hsiao-Yue Wee, Sher-Wei Lim, Jinn-Rung Kuo, Hong-Xiang Zheng, Chung-Ching Chio, Chin-Hung Chang, Chung-Han Ho
Publikováno v:
Neurochemical research. 45(7)
Injury severity is correlated with poor prognosis after traumatic brain injury (TBI). It is not known whether triglycerides (TGs) or total cholesterol (TC) is good biomarker of increased injury of neuroinflammation and apoptosis in a high fat diet (H