Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Chen Liang"'
Autor:
Jianwei Wang, Quanjie Li, Yu Huang, Shan Mei, Fei Guo, Xiaoxiao Zhao, Liang Wei, Di Zhang, Chao Wu, Xiaoman Liu, Chen Liang, Hong Sun, Siqi Hu, Fengwen Xu, Shan Cen, Zhangling Fan, Fei Zhao
Publikováno v:
J Biol Chem
Interferon-regulated myxovirus resistance protein B (MxB) is an interferon-induced GTPase belonging to the dynamin superfamily. It inhibits infection with a wide range of different viruses, including HIV-1, by impairing viral DNA entry into the nucle
Publikováno v:
Metabolites, Vol 11, Iss 424, p 424 (2021)
Metabolites
Metabolites
Skeletal muscle contraction relies on both high-fidelity calcium (Ca2+) signals and robust capacity for adenosine triphosphate (ATP) generation. Ca2+ release units (CRUs) are highly organized junctions between the terminal cisternae of the sarcoplasm
Publikováno v:
The Journal of Biological Chemistry
Viral proteins are known to be methylated by host protein arginine methyltransferases (PRMTs) necessary for the viral life cycle, but it remains unknown whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins are methylated. Her
Publikováno v:
Biochemical and Biophysical Research Communications. 514:187-193
A number of studies microRNAs (miRNA) play an important role in cardiac physiological and pathological processes. In these studies, miRNA regulates gene expression by repressing translation or directing sequence-specific degradation of complementary
Publikováno v:
Computational Biology and Chemistry. 80:390-397
Squalene synthase (SQS) is a potential target for hyperlipidemia treatment. To identify novel chemical scaffolds of SQS inhibitors, we generated 3D-QSAR pharmacophore models using HypoGen. The best quantitative pharmacophore model, Hypo 1, was select
Autor:
Tai-Lan Tuan, Ping Wu, Kylie Tanabe, Cheng-Ming Chuong, Randall B. Widelitz, David A. Kulber, Ya-Chen Liang, Yun-Shain Lee
Publikováno v:
Experimental Dermatology. 28:480-484
Keloids are wounding-induced fibroproliferative human tumor-like skin scars of complex genetic makeup and poorly defined pathogenesis. To reveal dynamic epigenetic and transcriptome changes of keloid fibroblasts, we performed RNA-seq and ATAC-seq ana
Publikováno v:
Journal of Cellular Biochemistry. 120:9047-9055
Myocardin is an important factor that regulates cardiac hypertrophy, and its activity can be regulated by GATA4. However, the molecular mechanism of the above process remains unclear. This paper presents three kinds of possible molecular mechanisms o
Autor:
Wei-Wan Zheng, Qiu-Shi Wang, Ming-Ming Wu, Chen Liang, Xu Yang, Zhi-Ren Zhang, Jie Lou, Bin-Lin Song, Liang-Liang Tang, Na Niu, He-Ping Ma
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Previous studies have shown that high salt induces artery stiffness by causing endothelial dysfunction via increased sodium influx. We used our unique split-open artery technique combined with protein biochemistry and in vitro measurement of vascular
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Lignin-carbohydrate complex (LCC) is the biological macromolecule that has been demonstrated to exert multiple biological functions, including antioxidant, anti-inflammation and anti-tumorigenesis, which support its broad application in the bioengine
Publikováno v:
Foodfunction. 11(10)
This study assessed the melanogenesis effects of rice protein hydrolysate (RPH) and explored the underlying molecular mechanism of its characteristic peptides. In this investigation, human epidermal melanocyte (PIG1) cells were used to establish a UV