Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Yu Yan"'
Autor:
Chun Xie, Min Huang, Qibiao Wu, Elaine Lai-Han Leung, Xiao-Jun Yao, Yi-Zhong Zhang, Ju-Min Huang, Ze-Bo Jiang, Xing-Xing Fan, Liang Liu, Yupo Ma, Pei-Yu Yan, Ya-Jia Xie, Cong Xu, Wen-Jun Wang, Xuan-Run Wang, Pei Liu
Publikováno v:
Cancer Letters. 515:36-48
Upregulated expression of immune checkpoint molecules correlates with exhausted phenotype and impaired function of cytotoxic T cells to evade host immunity. By disrupting the interaction of PD-L1 and PD1, immune checkpoint inhibitors can restore immu
Publikováno v:
Stem Cells and Development. 30:561-577
Acute myocardial infarction (AMI) is an event of ischemic myocardial necrosis caused by acute coronary artery occlusion, which ultimately leads to a large loss of cardiomyocytes. The prerequisite of salvaging ischemic myocardium and improving cardiac
Publikováno v:
Molecular Immunology. 131:44-50
Background Peripheral helper T (TPH) cells, a recently defined subset of Th cells, promote B cell differentiation and antibody production in inflamed tissues. This study investigated whether circulating TPH cells are associated with primary biliary c
Autor:
Stanislav Kopriva, Xiahe Huang, Junpeng Xie, Yingchun Wang, Yangwen Qian, Wei Wang, Liping Guo, Chengcai Chu, Xiujie Liu, Zhihua Zhang, Xiaohan Wang, Fanjiang Kong, Aifu Li, Shouyun Cao, Zhimin Jiang, Bin Hu, Li Zhao, Yu Yan, Baohui Liu, Legong Li, Yongqiang Liu, Yahong Qiu
Publikováno v:
Molecular Plant. 14:517-529
The coordinated utilization of nitrogen (N) and phosphorus (P) is vital for plants to maintain nutrient balance and achieve optimal growth. Previously, we revealed a mechanism by which nitrate induces genes for phosphate utilization; this mechanism d
Autor:
Glenn T. Stebbins, Kevin R Duque, Adam Margolius, Philip Saleh, Joaquin A. Vizcarra, Kelvin L. Chou, Alberto J. Espay, Diana Hengartner, Galit Kleiner, Hubert H. Fernandez, Alfonso Fasano, Albie Law, Michel Sáenz Farret, Yu-Yan Poon
Publikováno v:
Movement Disorders. 36:1392-1400
Background In patients with Parkinson's disease (PD), sleep, mood, cognitive, autonomic, and other non-motor symptoms may fluctuate in a manner similar to motor symptoms. Objectives To validate a final version of a patient-rated questionnaire that ca
Publikováno v:
Journal of Cellular Physiology. 236:6520-6533
Pre-eclampsia (PE) is a pregnancy-related disorder that occurs after 20 weeks of gestation. It seriously affects the health of maternity and the fetus. However, the pathogenesis of PE is still unknown. Decidualization deficiency is considered a contr
Autor:
Mojgan Hodaie, Andres M. Lozano, Renato P. Munhoz, Suneil K. Kalia, Cameron C. McIntyre, Alfonso Fasano, Marina Picillo, Sinem Balta Beylergil, Yu-Yan Poon, Onanong Phokaewvarangkul
Publikováno v:
Movement Disorders
Background No clinical trials have been specifically designed to compare medical treatments after surgery in Parkinson's disease (PD). Objective Study's objective was to compare the efficacy and safety of levodopa versus dopamine agonist monotherapy
Autor:
Yang Wang, Ming-Fei Du, Wei-Hua Gao, Bo-Wen Fu, Qiong Ma, Yu Yan, Yue Yuan, Chao Chu, Chen Chen, Yue-Yuan Liao, Ke Gao, Ke-Ke Wang, Min Li, Yue Sun, Jia-Wen Hu, Xin Chen, Dan Wang, Xiao-Yu Zhang, Chun-Hua Li, Hao-Wei Zhou, Wan-Hong Lu, Zu-Yi Yuan, John Chang, Jian-Jun Mu
Publikováno v:
European Journal of Clinical Nutrition. 75:531-538
Background/objectives Chronic kidney disease (CKD) is a global public health problem, including in China. The aim of this study was to identify the risk factors for the development and progression of subclinical renal disease (SRD) in a Chinese popul
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 791-802 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 791-802 (2020)
Transforming growth factor β (TGF-β)/Smad3 signaling plays a central role in chronic heart disease. Here, we report that targeting Smad3 with a Smad3 inhibitor SIS3 in an established mouse model of hypertension significantly improved cardiac dysfun
Autor:
Li‑Jie Zhang, Rong Wen, Hong Yang, Yong‑Ying Qin, Jun‑Lin Yang, Jun Wang, Deng‑Hua Pan, Yu‑Yan Pang, Qin‑Qiao Lai, Yu He, Jing‑Ni Lai, Xiao‑Jiao Li, Lin Shi, Jun Ma, Dong‑Yue Wen, Yun‑Hui Lai, Peng Lin
Publikováno v:
Molecular Medicine Reports
Thyroid cancer (TC) is a frequently occurring malignant tumor with a rising steadily incidence. microRNA (miRNA/miR)-193a-3p is an miRNA that is associated with tumors, playing a crucial role in the genesis and progression of various cancers. However