Zobrazeno 31 - 40
of 236
pro vyhledávání: '"Yu Yan"'
Publikováno v:
Plant Physiology and Biochemistry. 139:141-151
Proanthocyanidins (PAs) from plants are a nutritionally valuable component of the human diet and play important roles in defense against pests and diseases. PAs are products of the flavonoid pathway, which also leads to the production of anthocyanins
Autor:
Xiang Chen, Shijie Tang, Qing Wang, Can Liu, Huiqing Xie, Wei Chen, Zizi Chen, Jianda Zhou, Yu Yan, Aijun Wang
Publikováno v:
OncoTargets and Therapy. 12:4655-4663
Background: IMD-0354 is a kind of hydrophobic small molecule inhibitor of IKKβ, which can effectively inhibit the NF-κB pathway. Besides, IMD-0354 can inhibit a variety of tumor cells in culture, but its poor water solubility and low utilization ha
Autor:
Thi Hoang Anh Nguyen, Jin-ling Zhang, Ya-ying Chen, Xiang-yuan Song, Shisan Bao, Yu-yan Zhang, Jing-yi Zhang
Publikováno v:
International Immunopharmacology. 71:164-168
Glaucoma eventually leads to optic nerve damage and vision loss without medical intervention. More than 50% of glaucoma caused blindness are attributed to primary angle closure glaucoma, particularly in Asians. It is reported that immune inflammation
Autor:
Jing Su, Xin-Ru Zhong, Li-Chao Zhang, Sihang Yu, Xiao-Yu Yan, Yong Zhang, Liankun Sun, Yanan Liu
Publikováno v:
Journal of Cellular and Molecular Medicine
Increasing evidence suggests that p62/SQSTM1 functions as a signalling centre in cancer. However, the role of p62 in tumour development depends on the interacting factors it recruits and its precise regulatory mechanism remains unclear. In this study
Autor:
Li-Chao Zhang, Yao Wu, Xiao-Yu Yan, Liankun Sun, Rui Guo, Bingbing Yu, Yang Li, Jing Su, Jiuling Li, Ya-Nan Xue, Yanan Liu
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 8, Iss 5, Pp 2462-2473 (2019)
Cancer Medicine, Vol 8, Iss 5, Pp 2462-2473 (2019)
Metabolic reprogramming is a central hallmark of cancer. Therefore, targeting metabolism may provide an effective strategy for identifying promising drug targets for cancer treatment. In prostate cancer, cells undergo metabolic transformation from zi
Autor:
Nan Lou, Wen-Bin Li, Min Zhang, Xiao-Hui Xian, Hang Zhao, Meng-Yue Zhang, Jian-Xue Gong, Jing-Ge Zhang, Jie Qi, Yu-Yan Hu, A-Chou Su, Li Li, Cong-Cong Zhao, Ling-Yan Zhang
Publikováno v:
Brain Research Bulletin. 147:1-13
The previous studies have shown that glial glutamate transporter-1 (GLT-1) participates in cerebral ischemic injury in rats. However, the mechanism involved remains to be elucidated. This study was undertaken to investigate whether p38 MAPK was invol
Autor:
Guang Wang, Zhen-You Jiang, Ying-Jie Fu, Yu Yan, Xiao-tan Zhang, Xin Cheng, Yu-Qi Yan, Xuesong Yang
Publikováno v:
Infection, Genetics and Evolution. 69:176-189
Zika virus (ZIKV) infection during gestation is deemed to be coupled to birth defects through direct impairment of the nervous system during neurogenesis. However, in this study, our data showed that ZIKV infection dramatically suppressed cranial ost
Autor:
Jun Li, Xiao-Xin Zhang, Qing Li, Jian-Yu Yang, Yan-Li Zhang, Xiao-Mei Yang, Li-Peng Hu, Qin Yang, Jiang-Yu Yan, Xueli Zhang, Huizhen Nie, Yong-Sheng Jiang, Shu-Heng Jiang, Shangwei Hou, Zhigang Zhang, Shan Huang, Fangyuan Dong, Xiao-Yan Cao, Lili Zhu, Miao Dai, Rong Hua, Ce Zhang, Guang-Ang Tian, Kathy Qian Luo, Lei Zhu, Man Zhang, Yong-Wei Sun, Ling-Ye Tao, Rong-Kun Li, Jianren Gu, Ya-Hui Wang
Publikováno v:
Gut. 68:1994-2006
Background and aimsPancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related death worldwide. Neurotransmitter-initiated signalling pathway is profoundly implicated in tumour initiation and progression. Here, we investigated whethe
Publikováno v:
Cancer Management and Research. 11:1503-1515
Introduction Aquaporins (AQPs), also called water channels, have been shown to have functions in the migration, invasion, and proliferation of human breast tumor cells. Most AQP mRNA expression levels were tested by cell lines, mouse models, and even
Publikováno v:
Food and Nutrition Sciences. 10:1374-1387
Although a number of bioactive peptides are capable of angiotensin I-converting enzyme (ACE) inhibitory effects, little is known regarding the mechanism of hazelnut peptides using molecular simulation. In the present study, gel filtration chromatogra