Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Xiong Chen"'
Publikováno v:
Human & Experimental Toxicology. 40:1141-1152
Arsenic is a naturally occurring environmental toxicant, chronic exposure to arsenic can cause multiorgan damage, except for typical skin lesions, liver damage is the main problem for health concern in population with arsenic poisoning. Abnormal apop
Publikováno v:
Journal of Cellular Physiology. 236:4050-4065
Arsenic is an environmental toxicant. Its overdose can cause liver damage. Autophagy has been reported to be involved in arsenite (iAs3+ ) cytotoxicity and plays a dual role in cell proliferation and cell death. However, the effect and molecular regu
Autor:
Ruhong Li, Yanhong Zhou, Wei Xiong, Jianda Zhou, Fen Wang, Xiaohui Li, Fei Guo, Xiaoming Liu, Jianye Liu, Yuxing Zhu, Xiaoyan Wang, Ming Zhou, Qinghai Zeng, Qiang Wang, Xiaowei Xing, Ke Cao, Wen Xiao, Canxia Xu, Lian Gong, Hao Bo, Xiong Chen, Dong He
Publikováno v:
Hepatology. 72:2029-2050
Background and aims Hepatocellular carcinoma (HCC) is associated with high malignancy rates. Recently, a known deacetylase silent information regulator 1 (SIRT1) was discovered in HCC, and its presence is positively correlated with malignancy and met
Autor:
Mei Yoke Chan, Yvonne F. L. Yong, Derrick W. Q. Lian, Zhi Xiong Chen, Enrica E. K. Tan, Michaela S. F. Seng, Sharon Ling, Min Hwee Yong, Prasad Iyer, Yong Chen, Eileen H. Q. Ng, Yong Wei Chua, Esther Hee, Meng Kang Wong, Joyce Ching Mei Lam, Muhammad Fahmy Syed, Mee Hiong Ren, Amos Hong Pheng Loh, Sharon Y.Y. Low, Tony Kiat Hon Lim, Chik Hong Kuick, Kenneth Tou En Chang, Sudhanshi Jain, Sheng Hui Tan, Zhang'e Choo, Shui Yen Soh, Ah Moy Tan, Nurfarhanah Bte Syed Sulaiman
Publikováno v:
Cancer Science
Ex vivo evaluation of personalized models can facilitate individualized treatment selection for patients, and advance the discovery of novel therapeutic options. However, for embryonal malignancies, representative primary cultures have been difficult
Publikováno v:
Journal of Cellular and Molecular Medicine
Hypertension is the key factor for the development of cardiac fibrosis and diastolic dysfunction. Our previous study showed that knockout of sirtuin 3 (SIRT3) resulted in diastolic dysfunction in mice. In the present study, we explored the role of SI
Autor:
Xiayao Diao, Tianxin Lin, Weibin Xie, Lifang Huang, Hao Huang, Jianqiu Kong, Jian Huang, Chengran Huang, Shaoxu Wu, Junjiong Zheng, Haide Qin, Xiong Chen, Hao Yu, Jinhua Cai
Publikováno v:
Cancer Communications
Background The preoperative prediction of muscular invasion status is important for adequately treating bladder cancer (BC) but nevertheless, there are some existing dilemmas in the current preoperative diagnostic accuracy of BC with muscular invasio
Publikováno v:
The Asia Pacific Scholar, 5(3), 10-19. National University of Singapore
The Asia Pacific Scholar, Vol 5, Iss 3, Pp 10-19 (2020)
The Asia Pacific Scholar, Vol 5, Iss 3, Pp 10-19 (2020)
The expansion of biomedical sciences has seen a recent boom in the number of graduate students and early career scientists. However, the lack of motivation and increasing departure of graduates from research careers were not well explained in current
Autor:
Xiong Chen, Quazi Quamruzzaman, Hui Xu, Feng Chen, Junjie Li, Tian Xiao, Xiangyu Dai, Golam Mostofa, Qian Sun, Yongyue Wei, Dapeng Wang, Qizhan Liu, Aihua Zhang, Junchao Xue, Chao Chen
Publikováno v:
Toxicology Letters. 316:73-84
In the liver microenvironment, interactions among diverse types of hepatic cells are involved in liver fibrosis. In fibrotic tissues, exosomes act as transporters in intercellular communication. Long non-coding RNAs (lncRNAs) are involved in the acti
Autor:
Wei-Xiong Chen, Jing Gao, Xiao-Ya Zhang, Jin-Jun Qian, Jing Sun, Dong Chen, Qi-Jie Cong, Hafiz Muhammad Ahsan
Publikováno v:
Biomolecules & Therapeutics
This study sought to evaluate the effects of Asiatic acid in LPS-induced BV2 microglia cells and 1-methyl-4-phenyl-pyridine (MPP+)-induced SH-SY5Y cells, to investigate the potential anti-inflammatory mechanisms of Asiatic acid in Parkinson’s disea
Autor:
Xiaoming Liu, Canxia Xu, Qinghai Zeng, Jianye Liu, Xiong Chen, Ren-Jie Gong, Xingyu Chen, Yuxing Zhu, Mengqing Xiao, Ke Cao, Fen Wang
Publikováno v:
Cancers
Volume 13
Issue 14
Cancers, Vol 13, Iss 3475, p 3475 (2021)
Volume 13
Issue 14
Cancers, Vol 13, Iss 3475, p 3475 (2021)
Simple Summary Hepatocellular carcinoma (HCC) is characterized by a poor prognosis and high mortality rate, with complex molecular alterations, including glycosylation. O-linked N-acetylglucosamine (O-GlcNAc) is a dynamic modification process jointly