Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wei-Lun Hwang"'
Autor:
Li Chuan Chan, Ming-Feng Hou, Yi Hsin Hsu, Ying Nai Wang, Heng Huan Lee, Shouping Xu, Jun Yao, Jia Shen, Wei Lun Hwang, Wen Hao Yang, Chin Hua Yang, Lin Ming Tseng, Yufan Qiu, Shao Chun Wang, Gabriel N. Hortobagyi, Meisi Yan, Yongkun Wei, Zhou Jiang, Dihua Yu, Xifeng Wu, Jennifer L. Hsu, Yu Han Wang, Jong Ho Cha, Da Pang, Yuan-Liang Wang, Mei Ren Pan, Weiya Xia, Yuanqing Ye, Hirohito Yamaguchi, Mien Chie Hung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
Human ribonuclease 1 (hRNase 1) is critical to extracellular RNA clearance and innate immunity to achieve homeostasis and host defense; however, whether it plays a role in cancer remains elusive. Here, we demonstrate that hRNase 1, independently of i
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6829, p 6829 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6829, p 6829 (2021)
Volume 22
Issue 13
Orbital fibrosis, a hallmark of tissue remodeling in Graves’ ophthalmopathy (GO), is a chronic, progressive orbitopathy with few effective treatments. Orbital fibroblasts are effector cells, and transforming growth factor β1 (TGF-β1) acts as a cr
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1742, p 1742 (2021)
Cancers, Vol 13, Iss 1742, p 1742 (2021)
Simple Summary Head and neck squamous cell carcinomas (HNSCCs) are highly heterogeneous human malignancies associated with genetic and environmental factors. In HNSCCs, cancer stem cells (CSCs) provide the plasticity for cancer cell progression, meta
Autor:
Ko Hsun Liao, Ting Fen Tsai, Pei Ning Wang, Mel Campbell, Wei Lun Hwang, Wan Shan Yang, Hsing Jien Kung, Fang Shin Nian, Liang Kung Chen, Pei Ching Chang, Ming Wei Lin, Jin Wu Tsai, Chia Pei Yang, Chuan Chuan Chao, Tsai Yu Tzeng, Yuan Chi Teng, Yu Hui Wong, Kai Hsuan Wang, Ming Hsuan Chang
Publikováno v:
Aging Cell
In mammals, microRNAs can be actively secreted from cells to blood. miR‐29b‐3p has been shown to play a pivotal role in muscle atrophy, but its role in intercellular communication is largely unknown. Here, we showed that miR‐29b‐3p was upregu
Autor:
Ming Heng Wu, Chang Ta Chiou, Shyun Yeu Liu, Wen Chang Wang, Wei Lun Hwang, Tzu Hao Chang, Chi Hua Chang, Jung Wu Yang, Kuen Haur Lee, Wei Fan Chiang, Ji Dung Luo
Publikováno v:
Head & Neck. 40:1046-1056
Background Oral verrucous hyperplasia is commonly observed in the oral cavity of betel quid chewers and is a potential malignant disorder. However, the prognostic factors and genetic alterations of oral verrucous hyperplasia are unclear. Methods We c
Autor:
Chih Yung Yang, Yin Quan Chen, Jeng Kai Jiang, Chun Chi Lin, Chih Chan Lee, Hsin Yi Lan, Wei-Chung Cheng, Ruey Hwa Lu, Tzu Yu Yeh, Tsai Tsen Liao, Arthur Er Terg Chiou, Hung Hsin Lin, Shu Han Su, Wei Lun Hwang
Publikováno v:
Cancers, Vol 13, Iss 1833, p 1833 (2021)
Cancers
Volume 13
Issue 8
Cancers
Volume 13
Issue 8
Simple Summary Metastasis of tumor cells is the leading cause of death in cancer patients. Concurrent therapy with surgical removal of primary and metastatic lesions is the main approach for cancer therapy. Currently, therapeutic resistant properties
Publikováno v:
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-17 (2019)
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-17 (2019)
Background Cell-cell interactions maintain tissue homeostasis and contribute to dynamic alteration of the tumor microenvironment (TME). Communication between cancer and host cells not only promotes advanced disease aggression but also determines ther
Autor:
Wei Lun Hwang, Shyh Kuan Tai, Tsai Tsen Liao, Muh Hwa Yang, Wen Hao Hsu, Ting Lo, Hsin Yi Lan, Cheng-Chi Chang, Chien Hsin Ho
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 520-533 (2016)
SummaryLet-7 is crucial for both stem cell differentiation and tumor suppression. Here, we demonstrate a chromatin-dependent mechanism of let-7 in regulating target gene expression in cancer cells. Let-7 directly represses the expression of AT-rich i
Autor:
Wei Lun Hwang, Muh Hwa Yang, Chun Chi Lin, Hung Kai Chen, Chih Chan Lee, Ying Ju Kuo, Shyh Kuan Tai, Jiunn Chang Lin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
A favorable interplay between cancer cells and the tumor microenvironment (TME) facilitates the outgrowth of metastatic tumors. Because of the distinct initiating processes between primary and metastatic tumors, we investigate the differences in tumo
Autor:
Tse Shun Huang, Chuan Chi Shih, Wei Lun Hwang, Wen Wei Lin, Chi Hung Lin, Ko Hsun Liao, Oscar K. Lee, Muh Hwa Yang, Chen Li Chien, Hsin Chuan Chang, Shung Haur Yang, Te Chia Feng, Shing-Jyh Chang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0179758 (2017)
PLoS ONE, Vol 12, Iss 6, p e0179758 (2017)
Tissue angiogenesis is intimately regulated during embryogenesis and postnatal development. Defected angiogenesis contributes to aberrant development and is the main complication associated with ischemia-related diseases. We previously identified the