Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Minfeng Chen"'
Publikováno v:
Cancer Medicine, Vol 10, Iss 13, Pp 4437-4450 (2021)
Cancer Medicine
Cancer Medicine
Bladder cancer is a menace to global health worldwide due to its high recurrence rate and its progression to invasive muscular complications. Cell adhesion molecules play an intricate role in cancer migration, growth, and invasion. Therefore, through
Autor:
Peihua Liu, Huihuang Li, Minfeng Chen, Chaozhao Liang, Meng Zhang, Longfei Liu, Yu Cui, Hequn Chen, Hang Jin, Xiao-Long Zhang, Jinbo Chen, Xiongbing Zu, Jiao Hu
Publikováno v:
Journal of Cancer
Background: Bladder cancer is one of the most common malignancies in urologic system. The glucocorticoid-inducible kinase 2 (SGK2) expression and function were largely unknown in cancers. Current study was aimed to investigate the role of SGK2 in bla
Autor:
Yihai Cao, Jinrong Lin, Jincheng Zhong, Geni Ye, Weijin Lu, Jiayan Zhang, Ming Qi, Changzheng Shi, Xiaobo Li, Yunlong Yang, Minfeng Chen, Luyu Zhao, Wen-Cai Ye, An Hong, Jinghua Pan, Patrick Ming-Kuen Tang, Liangping Luo, Maohua Huang, Tongzheng Liu, Yong Li, Dong-Mei Zhang, Xukai Mo, Yiran Zhang
Publikováno v:
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, Vol 10, Iss 7, Pp n/a-n/a (2021)
Journal of Extracellular Vesicles, Vol 10, Iss 7, Pp n/a-n/a (2021)
Antiangiogenic tyrosine kinase inhibitors (AA‐TKIs) have become a promising therapeutic strategy for colorectal cancer (CRC). In clinical practice, a significant proportion of cancer patients temporarily discontinue AA‐TKI treatment due to recurr
Autor:
Wen-Cai Ye, Nan Yao, Chen-Ran Wang, Xiaobo Li, Minfeng Chen, Wei-Min Chen, Chun-Lin Fan, Mingqun Liu, Ming Qi, Jian Hong, Zhengqiu Li, Dong-Mei Zhang, Qi Qi, Ying-Jie Li, Jin-Jian Lu
Publikováno v:
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-13 (2020)
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-13 (2020)
Epidermal growth factor receptor (EGFR) activation plays a pivotal role in EGFR-driven non-small cell lung cancer (NSCLC) and is considered as a key target of molecular targeted therapy. EGFR tyrosine kinase inhibitors (TKIs) have been canonically us
Autor:
Lijuan Deng, Qing Wen, Dong-Mei Zhang, Geni Ye, Xiaobo Li, Maohua Huang, Weijin Lu, Jun Tang, Wen-Cai Ye, Rong Deng, Minfeng Chen
Publikováno v:
Cancer letters. 503
Tumor metastasis is the main cause of death in patients with triple-negative breast cancer (TNBC). Bone marrow-derived mesenchymal stem cells (BM-MSCs) have tropism towards tumor tissues, and can be converted into tumor-associated mesenchymal stromal
Autor:
Wenbiao Ren, Huihuang Li, Guanghui Gong, Peihua Liu, Anze Yu, Huihui Zhang, Xi Guo, Dongxu Qiu, Chao Li, Jinbo Chen, Minfeng Chen, Belaydi Othmane, Xiongbing Zu, Jiao Hu
Publikováno v:
Theranostics
Rationale: Siglec15 is an emerging target for normalization cancer immunotherapy. However, pan-cancer anti-Siglec15 treatment is not yet validated and the potential role of Siglec15 in bladder cancer (BLCA) remains elusive. Methods: We comprehensivel
Autor:
Xueping Lei, Jianyang Hu, Wen-Cai Ye, Yinghui Peng, Dong-Mei Zhang, Zhenjian Zhuo, Weiqian Mai, Minfeng Chen, Jun-Shan Liu, Lijuan Deng, Nan Yao, Liping Chen, Maohua Huang
Publikováno v:
Pharmacological Research. 123:130-142
Epithelial-mesenchymal transition (EMT) plays an important role in prostate cancer (PCa) metastasis; thus, developing EMT inhibitors may be a feasible treatment for metastatic PCa. Here, we discovered that arenobufagin and four other bufadienolides s
Autor:
Minfeng Chen, Longxiang Wu, Yangle Li, Xiheng Hu, Cheng Zhao, Yichuan Zhang, Zhi Wang, Shiyu Tong
Publikováno v:
Cellular Signalling. 84:110004
Uncontrolled proliferation and migration of benign prostatic hyperplasia (BPH) epithelial cells play a critical role in the pathogenesis of BPH. The regulatory roles of microRNAs (miRNAs) in multiple human diseases have been observed. This study was
Autor:
Heru Chen, Jianyang Hu, Nan Ma, Chunlin Fan, Dong-Mei Zhang, Xinyi Zhang, Weili Han, Baojian Wu, Nanhui Xu, Aihua Hong, Xiaobo Li, Qiulin Nie, Changzheng Shi, Minghan Xia, Maohua Huang, Qiang Yu, Ande Ma, Liangping Luo, Xueping Lei, Wen-Cai Ye, Bin Du, Hongsheng Li, Weiqian Mai, Zhengqiu Li, Minfeng Chen
Publikováno v:
Journal of Clinical Investigation. 127:3689-3701
Blood vessels in the tumor periphery have high pericyte coverage and are resistant to vascular disrupting agents (VDAs). VDA treatment resistance leads to a viable peripheral tumor rim that contributes to treatment failure and disease recurrence. Her
Publikováno v:
International Journal of Oncology. 51:677-685
Growth arrest-specific protein 6 (Gas6) induces the activation of Axl receptor tyrosine kinase (Axl), which plays an important role in angiogenic processes, including proliferation, migration, invasion, tube formation and pericyte recruitment of endo