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pro vyhledávání: '"Krystelle Godbout"'
Autor:
Ma'en Obeidat, Krystelle Godbout, Kim Valette, Philippe Joubert, Louis-Philippe Boulet, Sébastien Thériault, Maarten van den Berge, Patrick Mathieu, Arnaud Chignon, Catherine Labbé, Valentin Bon-Baret, Jean-Christophe Bérubé, Jennifer Lamothe, Nathalie Gaudreault, Aida Eslami, David C. Nickle, Ke Hao, Don D. Sin, Zhonglin Li, Michel Laviolette, Wim Timens, Andréanne Côté, Yohan Bossé
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, 4(1):700. Nature Publishing Group
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, 4(1):700. Nature Publishing Group
To identify candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls). We then carried out functional mapping through transcriptome-
Publikováno v:
Biochemical pharmacology. 179
Asthma is a chronic inflammatory disease of the airways affecting more than 300 million patients worldwide. The disease can be of various severity ranging from very mild to severe. The severe form of the disease only affects about 5% of patients but