Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Karthik, M."'
Autor:
Kaitlyn Thatcher, J. Will Thompson, Punashi Dutta, Karthik M. Kodigepalli, Joy Lincoln, Sarah Rains, Robert B. Hinton, Stephanie LaHaye, Casey Nagel
Publikováno v:
Circ Res
Rationale: Calcific aortic valve disease (CAVD) affects >5.2 million people in the United States. The only effective treatment is surgery, and this comes with complications and no guarantee of long-term success. Objective: Outcomes from pharmacologic
Publikováno v:
BMJ Case Rep
Adrenal myelolipomas represent a benign neoplasm with known associations with many chronic diseases, 21-hydroxylase deficiency and cancer. However, the aetiology of adrenal myelolipomas remains unknown. Here, we present a case of a patient with image
Autor:
Karthik M. Ganesh, Ajith Kumar Navin, Ilangovan Ramachandran, Sakhila K. Banu, Felicia Mary Michael, Mariajoseph Michael Aruldhas, G. Vengatesh, Sankar Venkatachalam, Jone A. Stanley, Sheerin L. Banu, Mohammad Abdulkader Akbarsha, Kathiresh M. Kumar, Shobana Navaneethabalakrishnan, Balaji Sadasivam
Publikováno v:
Reproductive Toxicology. 69:84-98
The effect of gestational exposure to CrVI (occupational/environmental pollutant and target to Sertoli cells(SC)) was tested in a rat model during the testicular differentiation from the bipotential gonad may interrupt spermatogenesis by disrupting S
Autor:
Karthik M. Kodigepalli, Shan-Lu Liu, Li Wu, Minghua Li, Serena Bonifati, Patrick L. Green, Amanda R. Panfil
Sterile alpha motif and HD domain-containing protein 1 (SAMHD1) is a mammalian dNTP hydrolase (dNTPase) and functions as a negative regulator in the efficacy of cytarabine treatment of acute myeloid leukemia (AML). We have reported that SAMHD1 knocko
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7966d17b4102e33c1a09794b92cd22a2
https://europepmc.org/articles/PMC6300106/
https://europepmc.org/articles/PMC6300106/
Autor:
Joy Lincoln, Frederick J. Schoen, Karthik M. Kodigepalli, Kaitlyn Thatcher, Daniel P. Howsmon, Christopher K. Breuer, Toni West, Michael S. Sacks
Publikováno v:
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease, Vol 7, Iss 57, p 57 (2020)
Journal of Cardiovascular Development and Disease, Vol 7, Iss 57, p 57 (2020)
Heart valves are dynamic structures that, in the average human, open and close over 100,000 times per day, and 3 × 109 times per lifetime to maintain unidirectional blood flow. Efficient, coordinated movement of the valve structures during the cardi
Autor:
Jenna M. Antonucci, Zhihua Qin, Li Wu, Olga Buzovetsky, Yong Xiong, Denis C. Guttridge, Mario L. Santiago, Katherine J. Ladner, Bradley S. Barrett, Jacob S. Yount, Corine St. Gelais, Karthik M. Kodigepalli, Kirsten M. Knecht, Serena Bonifati, Shuliang Chen, Sun Hee Kim
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(16)
Sterile alpha motif and HD-domain-containing protein 1 (SAMHD1) blocks replication of retroviruses and certain DNA viruses by reducing the intracellular dNTP pool. SAMHD1 has been suggested to down-regulate IFN and inflammatory responses to viral inf
Sterile alpha motif and HD domain-containing protein 1 (SAMHD1) is a mammalian dNTP hydrolase that acts as a negative regulator in the efficacy of cytarabine treatment against acute myeloid leukemia (AML). However, the role of SAMHD1 in AML developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec171e79e6b1e4d8f37fec5b3cac5b89
Sezary syndrome (SS) is a rare subtype of cutaneous T-cell lymphoma (CTCL) that is characterized by aggressive spread of neoplastic CD4+ T-cells from the skin into the bloodstream with metastasis to visceral organs. The deoxynucleoside triphosphohydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f346688d7e816970c87a9462a3e541d5
https://europepmc.org/articles/PMC5195900/
https://europepmc.org/articles/PMC5195900/
Autor:
Anthony A. Kossiakoff, Joseph A. Piccirilli, Jean-Louis K. Kouadio, Karthik M. Sundaram, Yilin Zhang, Ernst Lengyel, Katja Gwin, Anirban K. Mitra, Brian B. Roman
Publikováno v:
Cancer research. 77(7)
Poor prognosis of ovarian cancer, the deadliest of the gynecologic malignancies, reflects major limitations associated with detection and diagnosis. Current methods lack high sensitivity to detect small tumors and high specificity to distinguish mali