Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jonathan E. Kolitz"'
Autor:
Robert K. Stuart, Grerk Sutamtewagul, Ann-Kathrin Eisfeld, Ravi Vij, Krzysztof Mrózek, Jessica Kohlschmidt, Mohan Thakuri, Richard Stone, William Blum, Wendy Stock, Andrew J. Carroll, Jonathan E. Kolitz, Richard A. Larson, Guido Marcucci, Eunice S. Wang, Clara D. Bloomfield, Jun Yin, John C. Byrd, Alison Walker, Sawyer B. Jacobson
Publikováno v:
Blood Adv
Overexpression of B-cell leukemia/lymphoma 2 (BCL2) renders acute myeloid leukemia (AML) cells resistant to chemotherapy and has been associated with unfavorable outcomes. Oblimersen (G3139) is a phosphorothioate 18-mer antisense oligonucleotide dire
Autor:
Sophia E. Maharry, Clara D. Bloomfield, Marius Bill, Sandya Liyanarachchi, Christopher C. Oakes, Chi Song, Christopher J. Walker, Albert de la Chapelle, Geoffrey L. Uy, Brian Giacopelli, James S. Blachly, Bayard L. Powell, Eunice S. Wang, Shelley Orwick, Jonathan E. Kolitz, Richard Stone, Deedra Nicolet, Kellie J. Archer, Ann-Kathrin Eisfeld, John C. Byrd, Luke K Genutis, Jessica Kohlschmidt, Dimitrios Papaioannou, Krzysztof Mrózek, Andrew J. Carroll
Publikováno v:
Clin Cancer Res
Purpose:Uniparental disomy (UPD) is a way cancer cells duplicate a mutated gene, causing loss of heterozygosity (LOH). Patients with cytogenetically normal acute myeloid leukemia (CN-AML) do not have microscopically detectable chromosome abnormalitie
Autor:
Marius Bill, Bayard L. Powell, John C. Byrd, Brian Giacopelli, Jessica Kohlschmidt, Jonathan E. Kolitz, Dimitrios Papaioannou, Christopher C. Oakes, Ramiro Garzon, Krzysztof Mrózek, Richard Stone, Andrew J. Carroll, Ann-Kathrin Eisfeld, Deedra Nicolet, Clara D. Bloomfield
Publikováno v:
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-4 (2021)
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-4 (2021)
Recently, a novel knowledge bank (KB) approach to predict outcomes of individual patients with acute myeloid leukemia (AML) was developed using unbiased machine learning. To validate its prognostic value, we analyzed 1612 adults with de novo AML trea
Autor:
Clara D. Bloomfield, Bayard L. Powell, Andrew J. Carroll, Shelley Orwick, Ann-Kathrin Eisfeld, Jessica Kohlschmidt, Bhavana Bhatnagar, Dimitrios Papaioannou, Richard Stone, Deedra Nicolet, Krzysztof Mrózek, John C. Byrd, Jonathan E. Kolitz, Christopher J. Walker, James S. Blachly
Publikováno v:
Leukemia. 34:358-368
Sole trisomies of chromosomes 4, 8, 11, 13 and 21 account for 89–95% of all sole trisomies in adult AML patients. We analyzed clinical and molecular characteristics of 138 de novo AML patients with sole +4, +8, +11, +13 or +21, and compared them wi
Autor:
Jessica Kohlschmidt, Dimitrios Papaioannou, Clara D. Bloomfield, Paolo Fadda, Deedra Nicolet, Richard Stone, Andrew J. Carroll, John C. Byrd, Eunice S. Wang, Hatice Gulcin Ozer, Stefano Volinia, Jonathan E. Kolitz, Ramiro Garzon, Krzysztof Mrózek
Publikováno v:
Molecular Cancer Therapeutics. 18:1451-1459
We have previously shown that expression levels of 48 long noncoding RNAs (lncRNA) can generate a prognostic lncRNA score that independently associates with outcome of older patients with cytogenetically normal acute myeloid leukemia (CN-AML). Howeve
Autor:
Jonathan E. Kolitz, William Blum, Christopher J. Walker, Ann-Kathrin Eisfeld, Jessica Kohlschmidt, James S. Blachly, Dimitrios Papaioannou, Deedra Nicolet, Geoffrey L. Uy, Eunice S. Wang, Marius Bill, Richard Stone, Krzysztof Mrózek, Bayard L. Powell, Clara D. Bloomfield, Andrew J. Carroll, John C. Byrd
Publikováno v:
Leukemia
Complex karyotype (CK) with ≥ 3 abnormalities is detected in 10–12% of patients with acute myeloid leukemia (AML) and associated with poor prognosis. The most common unbalanced abnormalities found in CK result in loss of material from the 5q, 7q,
Autor:
Brian Giacopelli, Markus Scholz, Pamela Brock, Sebastian Schwind, Andrew J. Carroll, Marius Bill, Christopher C. Oakes, John C. Byrd, Dietger Niederwieser, Christopher J. Walker, Richard Stone, Krzysztof Mrózek, Eunice S. Wang, Ann-Kathrin Eisfeld, Jonathan E. Kolitz, Clara D. Bloomfield, Bayard L. Powell, Luke K Genutis, Sandya Liyanarachchi, Albert de la Chapelle, Jessica Kohlschmidt, Deedra Nicolet
Publikováno v:
Leukemia. 33:771-775
Autor:
Bayard L. Powell, Bhavana Bhatnagar, Alice S. Mims, Isaiah Boateng, Deedra Nicolet, Richard Stone, James S. Blachly, Shelley Orwick, Jessica Kohlschmidt, Ann-Kathrin Eisfeld, Albert de la Chapelle, Sophia E. Maharry, Jonathan E. Kolitz, Ramiro Garzon, Andrew J. Carroll, John C. Byrd, James L. Fisher, Krzysztof Mrózek, Electra D. Paskett, Brian Giacopelli, Qiuhong Zhao, Christopher C. Oakes, Christopher J. Walker
Publikováno v:
Cancer Discov
Clinical outcome of patients with acute myeloid leukemia (AML) is associated with cytogenetic and molecular factors and patient demographics (e.g., age and race). We compared survival of 25,523 non-Hispanic Black and White adults with AML using Surve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d28d2bb84fbfcea7e33723db08a26f1
https://europepmc.org/articles/PMC7933110/
https://europepmc.org/articles/PMC7933110/
Autor:
James S. Blachly, Ann-Kathrin Eisfeld, Richard Stone, Christopher J. Walker, Krzysztof Mrózek, Albert de la Chapelle, Bayard E. Powell, Andrew J. Carroll, Alice S. Mims, Deedra Nicolet, Jessica Kohlschmidt, Jonathan E. Kolitz, Dimitrios Papaioannou, Clara D. Bloomfield, John C. Byrd
Publikováno v:
Leukemia
The European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) have become an important tool to assess patients’ prognosis and guide treatment. We tested the prognostic impact of the 2017 ELN classificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899263e881c301e0751b5213e0cae6d1
https://europepmc.org/articles/PMC7882079/
https://europepmc.org/articles/PMC7882079/
Autor:
Adrienne M. Dorrance, Andrew J. Carroll, Deedra Nicolet, Ann-Kathrin Eisfeld, Allison E. Walker, Michał Świerniak, Christopher J. Walker, Felice Pepe, Krzysztof Mrózek, Marius Bill, Stefano Volinia, Richard Stone, Jonathan E. Kolitz, Jessica Kohlschmidt, Ramiro Garzon, Bayard L. Powell, Sakari Kauppinen, Andreas Petri, Dimitrios Papaioannou, Eunice S. Wang, Clara D. Bloomfield, Geoffrey L. Uy, John C. Byrd
Publikováno v:
Papaioannou, D, Volinia, S, Nicolet, D, Świerniak, M, Petri, A, Mrózek, K, Bill, M, Pepe, F, Walker, C J, Walker, A E, Carroll, A J, Kohlschmidt, J, Eisfeld, A-K, Powell, B L, Uy, G L, Kolitz, J E, Wang, E S, Kauppinen, S, Dorrance, A, Stone, R M, Byrd, J C, Bloomfield, C D & Garzon, R 2020, ' Clinical and functional significance of circular RNAs in cytogenetically normal AML ', Blood advances, vol. 4, no. 2, pp. 239-251 . https://doi.org/10.1182/bloodadvances.2019000568
Circular RNAs (circRNAs) are noncoding RNA molecules that display a perturbed arrangement of exons, called backsplicing. To examine the prognostic and biologic significance of circRNA expression in cytogenetically normal acute myeloid leukemia (CN-AM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c2eb89548dfe66eacf2fabbea796ed
https://vbn.aau.dk/ws/files/336993210/advancesadv2019000568.pdf
https://vbn.aau.dk/ws/files/336993210/advancesadv2019000568.pdf