Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jianqiang Hu"'
Autor:
Shanjie Wang, Mingming Zhang, Xinyu Feng, Tingting Liu, Jianqiang Hu, Dongdong Sun, Zhenyu Xiong, Zhijing Zhao, Haichang Wang, Jie Lin, Chuang Sun, Zhi Yang, Zheng Cheng, Yanhong Fan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:1905-1914
Mitochondrial dysfunction contributes to heart failure induced mortality in approximately 80% of diabetic patients. Mitophagy degrades defective mitochondria and maintains a healthy mitochondrial population, which is essential for cardiomyocyte survi
Autor:
Liang Zhang, Rui Song, Haichang Wang, Mingming Zhang, Dong Sun, Kaikai Hao, Baolin Guo, Xiaoming Gu, Gaoli Wei, Zhenyu Xiong, Jie Lin, Jing Gu, Jianqiang Hu, Dongdong Sun, Bo Wang, Congye Li, Wanrong Man
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Frontiers in Physiology
Cardiac remodeling and dysfunction are responsible for the high mortality after myocardial infarction (MI). We assessed the potential for Shank3 to alleviate the post-infarction cardiac dysfunction. The experimental MI mice model was constructed by l
Autor:
Jianqiang Hu, Lang Hu, Wangang Guo, Yuerong Xu, Feng Xue, Wei Zhang, Yan Li, Mingming Zhang, Yexian Fang, Dongwei Zhang, Dong Guo, Runze Wang
Publikováno v:
Journal of Cellular and Molecular Medicine
Cardiovascular diseases are a main cause of mortality whose prevalence continues to increase worldwide. Long non‐coding RNAs (lncRNAs) regulate a variety of biological processes by modifying and regulating transcription of coding genes, directly bi
Autor:
Jianhong Duan, Yingmei Zhang, Haichang Wang, Jie Lin, Zhijing Zhao, Wanrong Man, Lichao Hou, Mingming Zhang, Dongwei Zhang, Jianqiang Hu, Yanjie Guo, Dongdong Sun, Min Shen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:1962-1972
Myocardial infarction (MI), which is characterized by chamber dilation and left ventricular (LV) dysfunction, represents a major cause of morbidity and mortality worldwide. Polydatin (PD), a monocrystalline and polyphenolic drug isolated from a tradi
Autor:
Jianqiang Hu, Dongdong Sun, Zhijing Zhao, Rongqing Zhang, Jiaxing Wang, Mingming Zhang, Lei Zhang, Haichang Wang, Jie Lin, Wanrong Man, Erhe Gao, Wenjun Yu, Congye Li
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:1951-1961
The incidence and prevalence of heart failure (HF) in the world are rapidly rising possibly attributed to the worsened HF following myocardial infarction (MI) in recent years. Here we examined the effects of oncostatin M (OSM) on postinfarction cardi
Autor:
Ruhu Yan, Lichao Hou, Er-Fei Zhang, Xiaoying Zhao, Jinqi Yan, Jianqiang Hu, Dongdong Sun, Mingming Zhang, Ke Tu, Nan Li, Li Zhang
Publikováno v:
Apoptosis : an international journal on programmed cell death. 24(3-4)
Myocardial damage is responsible for the high mortality of sepsis. However, the underlying mechanism is not well understood. Cardiomyocyte autophagy alleviates the cardiac injury caused by myocardial infarction. Enhanced cardiomyocyte autophagy also
Autor:
Zhang Lei, Yu Duan, Haichang Wang, Tingting Wang, Jianqiang Hu, Dongdong Sun, Wanrong Man, Jie Lin, Mingming Zhang, Jiaxu Feng, Congye Li, Hongbing Jia, Lei Sun, Rongqing Zhang
Publikováno v:
Diabetologia. 59:2435-2447
Diabetic cardiomyopathy (DCM) is associated with suppressed autophagy and augmented apoptosis in the heart although the interplay between the two remains elusive. The ability of mammalian sterile 20-like kinase 1 to regulate both autophagy and apopto
Autor:
Xinyu Feng, Erhe Gao, Mingming Zhang, Jianqiang Hu, Haichang Wang, Dongdong Sun, Jie Lin, Shanjie Wang, Zheng Cheng, Tingting Wang
Publikováno v:
Journal of Cellular and Molecular Medicine
Apoptosis is associated with various myocardial diseases. Angiotensin II (Ang II) plays a central role in the pathogenesis of RAAS‐triggered cardiac apoptosis. Our previous studies showed that mammalian Ste20‐like kinase 1 (Mst1) aggravates cardi
Autor:
Erhe Gao, Jianqiang Hu, Dongdong Sun, Xinyu Feng, Haichang Wang, Shanjie Wang, Zhenyu Xiong, Jie Lin, Zhi Yang, Zheng Cheng, Tingting Wang
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1864(11)
Diabetic cardiomyopathy (DCM) is characterized by cardiac microvascular endothelial cells (CMECs) injury and cardiomyocyte (CM) dysfunction. Exosomes mediated cellular communication between CMECs and CM has emerging roles in the pathogenesis of DCM,
Autor:
Mingming Zhang, Jianqiang Hu, Tingting Wang, Erhe Gao, Dongdong Sun, Xinyu Feng, Haichang Wang, Shanjie Wang, Zheng Cheng, Jie Lin
Publikováno v:
Journal of molecular and cellular cardiology. 125
Aims Angiotension II (Ang II) plays a central role in the pathogenesis of renin-angiotensin-aldosterone system (RAAS)-induced heart failure. Mst1 exerts its function in cardiomyocytes subjected to pathological stimuli via inhibiting autophagy and agg