Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hitoshi Kashiwagi"'
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:448-452
Antibiotic-associated diarrhea (AAD) is a typical side effect of antibiotic treatment, especially in children. Amoxicillin (AMPC) and amoxicillin/clavulanate (AMPC/CVA) are associated with high risk of AAD; however, these antibiotics are important in
Publikováno v:
Biologicalpharmaceutical bulletin. 43(10)
The anti-inflammatory agent colchicine may cause toxic effects such as rhabdomyolysis, pancytopenia, and acute respiratory distress syndrome in cases of overdose and when patients have renal or liver impairment. As colchicine is a substrate for CYP3A
Autor:
Toshikatsu Okumura, Fumiaki Kojima, Yoshitaka Imamichi, Koh-ichi Yuhki, Shuh Narumiya, Hitoshi Kashiwagi, Fumitaka Ushikubi, Shima Kumei
Publikováno v:
The FASEB Journal. 32:2354-2365
Nonalcoholic steatohepatitis (NASH) is a hepatic manifestation of metabolic syndrome. Although the prostaglandin (PG)I2 receptor IP is expressed broadly in the liver, the role of PGI2-IP signaling in the development of NASH remains to be determined.
Autor:
Yoshikazu Tasaki, Fumiaki Kojima, Koh-ichi Yuhki, Shuh Narumiya, Hitoshi Kashiwagi, Shima Kumei, Yoshitaka Imamichi, Fumitaka Ushikubi
Publikováno v:
Thrombosis and haemostasis. 119(8)
Platelets play an important role in both physiological hemostasis and pathological thrombosis. Thromboxane (TX) A2 and prostaglandin (PG) I2 are well known as a potent stimulator and an inhibitor of platelet function, respectively. Recently, PGE2 has
Autor:
Yoh Takekuma, Ken Iseki, Masaki Kobayashi, Takayuki Miyai, Mitsuru Sugawara, Hitoshi Kashiwagi, Shungo Imai
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236789 (2020)
PLoS ONE
PLoS ONE
Artificial neural networks are the main tools for data mining and were inspired by the human brain and nervous system. Studies have demonstrated their usefulness in medicine. However, no studies have used artificial neural networks for the prediction
Autor:
Hitoshi Kashiwagi, Takashi Yazawa, Reiko Okada, Satoru Takahashi, Takeshi Kitano, Takanobu Taniguchi, Koh-ichi Yuhki, Rafiqul Islam Khan, Kaoru Miyamoto, Yoshitaka Imamichi, Fumitaka Ushikubi, Takashi Kajitani, Yoshihiko Inaoka, Junsuke Uwada, Asuka Mano, Tariqul Islam, Nobuo Suzuki, Takahiro Nemoto, Toshio Sekiguchi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Diethylstilbestrol (DES), a strong estrogenic compound, is well-known to affect the reproductive system. In this study, we investigated the effects of DES administration on gonadotropin levels and ovarian steroidogenesis in prepubertal rats. DES trea