Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Haijing Wu"'
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 3, Pp 649-665 (2021)
Immunity, Inflammation and Disease
Immunity, Inflammation and Disease
Absent in melanoma 2 (AIM2) is a novel member of interferon (IFN)‐inducible PYHIN proteins. In innate immune cells, AIM2 servers as a cytoplasmic double‐stranded DNA sensor, playing a crucial role in the initiation of the innate immune response a
Publikováno v:
Clinical Reviews in Allergy & Immunology. 60:220-243
G protein-coupled receptors (GPCRs) constitute the largest family of plasma membrane receptors in nature and mediate the effects of a variety of extracellular signals, such as hormone, neurotransmitter, odor, and light signals. Due to their involveme
Publikováno v:
Clinical Reviews in Allergy & Immunology. 62:273-291
There are two major clinical subsets of scleroderma: (i) systemic sclerosis (SSc) is a complex systemic autoimmune disorder characterized by inflammation, vasculopathy, and excessive fibrosis of the skin and multiple internal organs and (ii) localize
Publikováno v:
Clinical Reviews in Allergy & Immunology. 60:68-86
Complex composition is one of the most important features of the immune system, involving many types of organs, tissues, cells, and molecules that perform immune functions. The normal function of each component of the immune system is the guarantee f
Publikováno v:
Expert Review of Clinical Immunology. 16:829-837
Between 5 and 25% of patients with cutaneous lupus erythematosus (CLE) can progress to systemic lupus erythematosus (SLE) during the course of the disease. There is no clear predictive guideline for the progression of CLE to SLE.Lupus erythematosus (
Publikováno v:
International Reviews of Immunology. 39:174-187
Laboratory animal models are beneficial when they recapitulate all or just some of the clinical and immunological manifestations of the disease. Various animals such as cats, rats, dogs, hamsters, guinea pigs, rabbits, horses, minks, pigs, and primat
Publikováno v:
Cell Mol Immunol
Innate lymphoid cells (ILCs), as an important component of the innate immune system, arise from a common lymphoid progenitor and are located in mucosal barriers and various tissues, including the intestine, skin, lung, and adipose tissue. ILCs are he
Publikováno v:
Autoimmunity. 53:192-200
Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by abnormal T and B cells. B-cell activating factor (BAFF) has been suggested to play a crucial role in lupus by promoting the proliferation, differentiation, and survi
Publikováno v:
Autoimmunity. 53:122-136
The evidence indicates that microRNAs (miRNAs) can regulate gene expression and play an important role in the pathogenesis of autoimmune diseases, yet studies on expression profiles of miRNAs are still inconclusive. Our objective is to identify miRNA
Publikováno v:
Autoimmunity. 53:56-64
Systemic lupus erythematosus (SLE) is an autoimmune disease that often occurs in females of child-bearing age. It involves multiple systems and severely threatens human life. One of the typical characteristics of SLE is the formation of immune comple