Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Bhagwat, A"'
Autor:
Hem Chandra Jha, Hamendra Singh Parmar, Rajesh Sharma, Pramod K. Gavel, Aakruti Nayak, Shivani Bhagwat
Publikováno v:
Current Cancer Drug Targets. 21:575-600
Cancer patients are more susceptible to COVID-19; however, the prevalence of COVID-19 in different types of cancer is still inconsistent and inconclusive. Here, we delineate the intricate relationship between breast cancer and COVID-19. Breast cancer
Autor:
Havish Shukla, Rakesh K. Tekade, HariPriya Koppisetti, Shreya Pande, Aayushi S. Ditani, Pragyan Paramita Mallick, Kiran Kalia, Umesh Kathar, Nimeet Desai, Bhagwat Sirsat
Publikováno v:
Future Medicinal Chemistry. 13:663-686
Globally, diabetic nephropathy (DN) is the foremost cause of end-stage renal disease. With the incidence of diabetes increasing day by day, DN's occurrence is expected to surge to pandemic proportions. Current available therapeutic interventions asso
Publikováno v:
Plant Genetic Resources: Characterization and Utilization. 19:122-132
Khasi mandarin (Citrus reticulata Blanco) is a commercial mandarin variety grown in northeast India and one of the 175 Indian food items included in the global first food atlas. The cultivated plantations of Khasi mandarin grown prominently in the lo
Publikováno v:
Journal of Biotechnology. 330:27-34
The bacteriolysin lysostaphin (Lst) and endolysin PlyPH are potent modular lytic enzymes with activity against clinically-relevant Gram-positive Staphylococcus aureus and Bacillus cereus, respectively. Both enzymes possess an N-terminal catalytic dom
Autor:
Margaret K. Wilkens, Monica Musteanu, Aine Knott, Magda Bahcall, Shripad V. Bhagwat, Kara M. Soroko, Prafulla C. Gokhale, Jens Köhler, Emily S. Chambers, Mika Lin, Yutong Zhao, Hong L. Tiv, Jihyun Choi, Jason Manro, Ramon V. Tiu, Arrien A. Bertram, Pasi A. Jänne, Atsuko Ogino, Cloud P. Paweletz, Jiaqi Li, Chiara Ambrogio
Publikováno v:
Molecular Cancer Therapeutics. 20:641-654
RAS gene mutations are the most frequent oncogenic event in lung cancer. They activate multiple RAS-centric signaling networks among them the MAPK, PI3K, and RB pathways. Within the MAPK pathway, ERK1/2 proteins exert a bottleneck function for transm
Autor:
Hong Lin, Richard Koche, Stephanie Braunstein, Anouar Zouak, Bing Li, Aliaksandra Radzisheuskaya, Peggy Scherle, Min Wang, Aishwarya Krishnan, Kris Vaddi, Young C. Park, Raajit K. Rampal, Abdul Karzai, Neha Bhagwat, Benjamin H. Durham, Aaron D. Viny, Friederike Pastore, Robert L. Bowman, Alexander Grego, Wenbin Xiao, Ross L. Levine, Keith B. Cordner, Jesper L.V. Maag, Jaanvi Mehta, Kristian Helin, Alessandro Pastore
Publikováno v:
Cancer Discovery. 10:1742-1757
We investigated the role of PRMT5 in myeloproliferative neoplasm (MPN) pathogenesis and aimed to elucidate key PRMT5 targets contributing to MPN maintenance. PRMT5 is overexpressed in primary MPN cells, and PRMT5 inhibition potently reduced MPN cell
Autor:
Ashlesha Bhagwat, Unnati Padalia
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 18, Iss 1, Pp 1-9 (2020)
Journal of Genetic Engineering & Biotechnology
Journal of Genetic Engineering & Biotechnology
Background Prodigiosin is a naturally occurring red pigment by Serratia marcescens and having enormous medicinal properties. Recently, there is a need to develop a high-throughput and economically feasible bioprocess for the production of prodigiosin
Publikováno v:
Molecular Pharmacology. 98:234-242
We previously established that androgen glucuronides are primarily effluxed by MRP2 and MRP3 in liver and intestine. However, no data exist on the mechanism of hepatic uptake of these metabolites. To fill this knowledge gap, the first goal of this st
Autor:
Douglas Senalik, Dorothea Tholl, Suzanne Laliberte, Shelby Ellison, Andrew Muchlinski, Susan R. Whitehead, Philipp W. Simon, Mwafaq Ibdah, Bhagwat Nawade, Mossab Yahyaa
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Carrot (Daucus carota L.) is an important root vegetable crop with high nutritional value, characteristic flavor, and benefits to human health. D. carota tissues produce an essential oil that is rich in volatile terpenes and plays a major role in car
Autor:
Ramon V. Tiu, Michael John Rodriguez, Meghann Pogue, Baohui Zhao, Denis J. McCann, Xiu-Juan Yuan, Wenjuan Wu, William T. McMillen, Shufen Cai, Robert S. Flack, Gregory D. Plowman, Jason Manro, Shripad V. Bhagwat, Matthew Whitesell, Andrew J. Dropsey, Eunice Yuen, Robert D. Van Horn, Lisa Kindler, Sajan Joseph, Jennie L. Walgren, Yan Zhai, Xi Rao, Sheng-Bin Peng, Weihua Shen, Bryan D. Anderson
Publikováno v:
Molecular Cancer Therapeutics. 19:325-336
The ERK pathway is critical in oncogenesis; aberrations in components of this pathway are common in approximately 30% of human cancers. ERK1/2 (ERK) regulates cell proliferation, differentiation, and survival and is the terminal node of the pathway.