Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Bart Staels"'
Autor:
Marcus Ståhlman, Patrick Schrauwen, Carlijn M. E. Remie, Pandichelvam Veeraiah, Martijn C. G. J. Brouwers, Bas Havekes, Yvonne M. H. Bruls, Vera B. Schrauwen-Hinderling, Esther Phielix, Renée de Mutsert, Marja-Riitta Taskinen, Kay H. M. Roumans, Lucas Lindeboom, Jan Borén, Bart Staels, Marjan Alssema, Harry P. F. Peters
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.1891. ⟨10.1038/s41467-020-15684-0⟩
Nature Communications, 11(1):1891. Nature Publishing Group
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.1891. ⟨10.1038/s41467-020-15684-0⟩
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Nature Communications
Nature Communications, 2020, 11 (1), pp.1891. ⟨10.1038/s41467-020-15684-0⟩
Nature Communications, 11(1):1891. Nature Publishing Group
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.1891. ⟨10.1038/s41467-020-15684-0⟩
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Hepatic steatosis is associated with poor cardiometabolic health, with de novo lipogenesis (DNL) contributing to hepatic steatosis and subsequent insulin resistance. Hepatic saturated fatty acids (SFA) may be a marker of DNL and are suggested to be m
Autor:
Sarah Costantino, Przemyslaw Blyszczuk, Johan Auwerx, Melanie Greter, Anne Tailleux, Urs Eriksson, Julien Weber, Christian M. Matter, Simona Stivala, Sokrates Stein, Jürg H. Beer, Melroy X. Miranda, Bart Staels, Thomas F. Lüscher, Kathrin Nussbaum, Tasneem Arsiwala, Burkhard Becher, Francesco Paneni, Raul Mostoslavsky, Michael O. Hottiger, Lavinia Bisceglie, Lambertus J. van Tits, Daniel S. Gaul, Jürgen Pahla
Publikováno v:
Journal of Molecular and Cellular Cardiology. 139:24-32
Aims Sirtuin 6 (Sirt6) is a NAD+-dependent deacetylase that plays a key role in DNA repair, inflammation and lipid regulation. Sirt6-null mice show severe metabolic defects and accelerated aging. Macrophage-foam cell formation via scavenger receptors
Autor:
Bart Staels, Charlène Pourpe, E. Eury, Christine Laborie, Didier Vieau, Emmanuelle Vallez, Philippe Froguel, Anne Delmont, Anne Tailleux, Simon Lecoutre, Anne Dickes-Coopman, Pierre Daubersies, Christophe Breton, Jean Lesage, Marie Verbanck, Valérie Montel
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 317:E1094-E1107
Clinical and animal studies have reported an association between low birth weight and the development of nonalcoholic fatty liver disease (NAFLD) in offspring. Using a model of prenatal maternal 70% food restriction diet (FR30) in the rat, we previou
Publikováno v:
Nature Reviews Cardiology
Nature Reviews Cardiology, 2021, Online ahead of print. ⟨10.1038/s41569-021-00569-6⟩
Nature Reviews Cardiology, Nature Publishing Group, 2021, Online ahead of print. ⟨10.1038/s41569-021-00569-6⟩
Nature Reviews Cardiology, 2021, Online ahead of print. ⟨10.1038/s41569-021-00569-6⟩
Nature Reviews Cardiology, Nature Publishing Group, 2021, Online ahead of print. ⟨10.1038/s41569-021-00569-6⟩
International audience; Peroxisome proliferator-activated receptor-α (PPARα), PPARδ and PPARγ are transcription factors that regulate gene expression following ligand activation. PPARα increases cellular fatty acid uptake, esterification and tra
Publikováno v:
Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2021, 1867 (5), pp.166097. ⟨10.1016/j.bbadis.2021.166097⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, 2021, 1867 (5), pp.166097. ⟨10.1016/j.bbadis.2021.166097⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2021, 1867 (5), pp.166097. ⟨10.1016/j.bbadis.2021.166097⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, 2021, 1867 (5), pp.166097. ⟨10.1016/j.bbadis.2021.166097⟩
International audience; Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and transcriptional modulators with crucial functions in hepatic and whole-body energy homeostasis. Besides their well-documented roles in lipid and glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85044d9a789d73efe8680e72af3b19b3
https://www.hal.inserm.fr/inserm-03176517
https://www.hal.inserm.fr/inserm-03176517
Autor:
Alessio Luzi, Ottavia Porzio, Rainer H. Böger, Arianna Massimi, Rossella Menghini, Andrea Magrini, Nikolaus Marx, Massimo Federici, Juliane Hannemann, Maria Mavilio, Peter J. Grant, Stefano Rizza, Michael Lehrke, Bart Staels, Marta Ballanti
Publikováno v:
Acta Diabetologica
Objective To detect premature gluco-metabolic defects among night shift workers with disturbances in circadian rhythms. Design and methods We performed a hypothesis-generating, cross-sectional analysis of anthropometric, metabolic, lipid, and inflamm
Autor:
Denis A. Mogilenko, Delphine Staumont-Sallé, Geert van Loo, Wim Declercq, Peter Vandenabeele, Michael Devos, David Dombrowicz, Peter Tougaard, C. Becquart, Claus Bachert, Sandrine Quemener, Bart Staels, Barbara Gilbert, Hélène Dehondt, Sébastien Fleury
Publikováno v:
Journal of Investigative Dermatology. 139:135-145
Keratinocytes are key players in chronic inflammatory skin diseases. A20 regulates NF-κB-dependent expression of proinflammatory genes and cell death, but the impact of its expression in keratinocytes on systemic inflammation and skin disorders has
Autor:
Kevin Kasprzak, Stéphanie Mouton, Sandro Ninni, Brieuc Noirot-Cosson, H. Ridon, Bart Staels, Claire Seunes, François Pontana, Staniel Ortmans, Augustin Coisne, Cedric Klein, Benjamin Longère, Patrizio Lancellotti, Laurent Davin, Amandine Coppin, David Montaigne
Publikováno v:
The International Journal of Cardiovascular Imaging. 35:267-273
Both genetic and environmental factors interact to control left ventricular (LV) remodeling in the context of aortic stenosis (AS). Epicardial adipose tissue (EAT) is a specific visceral adipose tissue with paracrine properties in close contact with
Autor:
Antoine Rauch, Guillaume Lefèvre, Alain Duhamel, Anne Bauters, Eric Kipnis, Natacha Rousse, Senna Staessens, Pauline Varlet, Sophie Susen, Annabelle Dupont, Julien Labreuche, Bart Staels, Morgan Caplan, Flavien Vincent, Julien Poissy, Marc Lambert, Mickael Rosa, Mouhamed Moussa, Simon F. De Meyer, Julien Goutay, Karine Faure, Fanny Lassalle, Delphine Corseaux, Delphine Garrigue, Emmanuelle Jeanpierre, Peter J. Lenting
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 41(5)
Objective: Whether endotheliopathy only mirrors coronavirus disease 2019 (COVID-19) severity or plays an intrinsic role in microvascular thrombosis and organ failure remains unanswered. We assessed whether markers of endothelial damage and immune dys
Autor:
Marlène Maitre, Astrid Cannich, Julie Charton, Alexia Duveau, Giovanni Marsicano, Valentine Guinot, Valérie S. Fénelon, Ashley Castellanos-Jankiewicz, Delphine Gonzales, Gilles Mithieux, Omar Guzmán-Quevedo, Kristina Schoonjans, Sandrine Quemener, Catherine Piveteau, Philippe Zizzari, Vincent Simon, Vincent Prevot, Nathalie Hennuyer, Fredrik Bäckhed, Nathalie Dupuy, Samantha Clark, Camille Allard, Daniela Fernandois, Bart Staels, Daniela Cota, Marcus Henricsson, Thierry Leste-Lasserre, Alessia Perino, Carmelo Quarta, David Dombrowicz, Benoit Deprez, Luigi Bellocchio, Anne Tailleux
Publikováno v:
Cell Metabolism
Cell Metabolism, 2021, 33 (7), pp.1483-1492.e10. ⟨10.1016/j.cmet.2021.04.009⟩
Cell Metabolism, Elsevier, 2021, Online ahead of print. ⟨10.1016/j.cmet.2021.04.009⟩
Cell Metabolism, 2021, 33 (7), pp.1483-1492.e10. ⟨10.1016/j.cmet.2021.04.009⟩
Cell Metabolism, Elsevier, 2021, Online ahead of print. ⟨10.1016/j.cmet.2021.04.009⟩
International audience; Bile acids (BAs) improve metabolism and exert anti-obesity effects through the activation of the Takeda G protein-coupled receptor 5 (TGR5) in peripheral tissues. TGR5 is also found in the brain hypothalamus, but whether hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8e0b6ce73c10e7979f80c2f7767e1b
https://www.hal.inserm.fr/inserm-03257931
https://www.hal.inserm.fr/inserm-03257931