Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Antrix Jain"'
Autor:
Ramona Curpan, Balkees Abderrahman, Yue Chen, Debra A. Tonetti, Rui Xiong, Sean W. Fanning, Jay S. Hanspal, Charles E. Foulds, Ping Fan, Antrix Jain, Anna Malovannaya, Gregory R. J. Thatcher, V. Craig Jordan, Geoffrey L. Greene, Philipp Y. Maximov
Publikováno v:
Mol Cancer Ther
Patients with long-term estrogen-deprived breast cancer, after resistance to tamoxifen or aromatase inhibitors develops, can experience tumor regression when treated with estrogens. Estrogen's antitumor effect is attributed to apoptosis via the estro
Autor:
Ayse L. Mindikoglu, Antone R. Opekun, Zoe R. Wilhelm, Mustafa M. Abdulsada, Antrix Jain, Sung Yun Jung, Sridevi Devaraj, Prasun K. Jalal
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Metabolic syndrome is characterized by central obesity, insulin resistance, elevated blood pressure, and dyslipidemia. Metabolic syndrome is a significant risk factor for several common cancers (e.g., liver, colorectal, breast, pancreas). Pharmacolog
Autor:
Yu Chen Du, Antrix Jain, Sung Yun Jung, Xiao-Nan Li, Xiang Chen, John Hicks, Justin M M Cates, Tsz-Kwong Man
Publikováno v:
Molecular Oncology, Vol 14, Iss 4, Pp 846-864 (2020)
Molecular Oncology
Molecular Oncology
The development of pulmonary metastasis is the leading cause of death in osteosarcoma (OS), which is the most common malignant bone tumor in children. We have previously reported that the tumor suppressor p27 (KIP1, CDKN1B) is frequently mislocalized
Autor:
Richard N. Sifers, Carolyn J. Adamski, Antrix Jain, Kaifang Pang, J. Lloyd Holder, Sung Yun Jung, Huda Y. Zoghbi, Zhandong Liu, Li Wang, Vitaliy V. Bondar, Evelyn Craigen, John R. Collette, Kihoon Han
Publikováno v:
Molecular psychiatry
Neurons are sensitive to changes in the dosage of many genes, especially those regulating synaptic functions. Haploinsufficiency of SHANK3 causes Phelan-McDermid syndrome and autism, whereas duplication of the same gene leads to SHANK3 duplication sy
Autor:
Sung Yun Jung, Matthew J. Ellis, Purba Singh, Hamssika Chandrasekaran, Antrix Jain, Anna Malovannaya, Doug W. Chan, Lacey E. Dobrolecki, Jong M. Choi, Alexander B. Saltzman, Bhoomi Bhatt, Mei Leng, Michael T. Lewis
Publikováno v:
Molecular & Cellular Proteomics. 17:2270-2283
In quantitative mass spectrometry, the method by which peptides are grouped into proteins can have dramatic effects on downstream analyses. Here we describe gpGrouper, an inference and quantitation algorithm that offers an alternative method for assi
Autor:
Axel Loredo, Yuda Chen, Chenfei Yu, Aviva Gordon, Juan Tang, Sung Yun Jung, Antrix Jain, Han Xiao
Publikováno v:
Bioconjugate Chemistry. 29:3522-3526
Site-specific antibody conjugates with a well-defined structure and superb therapeutic index are of great interest for basic research, disease diagnostics, and therapy. Here, we develop a novel proximity-induced antibody conjugation strategy enabling
Autor:
Antrix Jain, Yue Chen, Ross Han, Ramona Curpan, Anna Malovannaya, Geoffrey L. Greene, Yousef M Hawsawi, Charles E. Foulds, Bradley M. Broom, Philipp Y. Maximov, Sean W. Fanning, V. Craig Jordan, Daniela M. Quintana Rincon, Balkees Abderrahman, Jeffery A. Greenland, Ping Fan
Publikováno v:
Molecular Pharmacology
High-dose synthetic estrogen therapy was the standard treatment of advanced breast cancer for three decades until the discovery of tamoxifen. A range of substituted triphenylethylene synthetic estrogens and diethylstilbestrol were used. It is now kno
Autor:
Melissa Paola Mezzari, Antone R. Opekun, Ayse L. Mindikoglu, Jong Min Choi, Sridevi Devaraj, Joseph F. Petrosino, Prasun K. Jalal, Antrix Jain, Sung Yun Jung, Mustafa M. Abdulsada
Publikováno v:
J Proteomics
Murine studies showed that disruption of circadian clock rhythmicity could lead to cancer and metabolic syndrome. Time-restricted feeding can reset the disrupted clock rhythm, protect against cancer and metabolic syndrome. Based on these observations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd362fe6f97c90884bd9096b539596d
https://europepmc.org/articles/PMC7429999/
https://europepmc.org/articles/PMC7429999/
Autor:
Tawfik Issa, Hamed M A Mutwally, Gamal Osman, Antrix Jain, Sung Yun Jung, Osama Mohamed M Sarhan, Mohamed M. El-Mogy
Publikováno v:
Biology
Volume 9
Issue 1
Volume 9
Issue 1
We investigated the early risk of developing cancer by inhalation of low doses (60 µ
L/day) of methyl tertiary butyl ether (MTBE) vapors using protein SDS-PAGE and LC-MS/MS analysis of rat sera. Furthermore, histological alterations were as
L/day) of methyl tertiary butyl ether (MTBE) vapors using protein SDS-PAGE and LC-MS/MS analysis of rat sera. Furthermore, histological alterations were as
Autor:
Daniela F. Felice, Antrix Jain, Benjamin Deneen, Chia-Ching John Lin, Brittney Lozzi, Debosmita Sardar, Junsung Woo, Adriana Paulucci-Holthauzen, Navish A. Bosquez Huerta, Anna Yu-Szu Huang
Publikováno v:
Trends Immunol
Neuron
Neuron
Astrocytes play essential roles in brain function by supporting synaptic connectivity and associated circuits. How these roles are regulated by transcription factors is unknown. Moreover, there is emerging evidence that astrocytes exhibit regional he