Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Amanda B. Muir"'
Autor:
Kathleen E. Sullivan, Kelly Maurer, Li Song, Jonathan M. Spergel, Melanie A. Ruffner, Joshua X. Wang, Amanda B. Muir, Margaret Carroll, Lihua Shi
Publikováno v:
Allergy
Background Germline-encoded innate immune pattern recognition receptors (PRR) are expressed at epithelial surfaces and modulate epithelial defenses. Evidence suggests that stimulation of the Toll-like receptor (TLR) family of PRR may regulate epithel
Autor:
Manabu Muto, Masataka Shimonosono, Takaaki Arigami, Amanda B. Muir, Masaki Mori, Takashi Kijima, Yuta Kasagi, Shinya Ohashi, Andres J. Klein-Szanto, Prasanna M. Chandramouleeswaran, Narayan G. Avadhani, Itaru Omoto, Shoji Natsugoe, Gregory G. Ginsberg, Seiji Naganuma, Veronique Giroux, Varun Sahu, Yoshiaki Shinden, Osamu Kikuchi, Devraj Basu, J. Alan Diehl, Yasuto Uchikado, Koji Tanaka, Yoshiaki Kita, Yuichiro Doki, Adam J. Bass, Ken Sasaki, Hiroshi Nakagawa, Anil K. Rustgi, Kelly A. Whelan, Takeo Hara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Background & Aims Oropharyngeal and esophageal squamous cell carcinomas, especially the latter, are a lethal disease, featuring intratumoral cancer cell heterogeneity and therapy resistance. To facilitate cancer therapy in personalized medicine, thre
Autor:
Bailey Aaron, Masataka Shimonosono, Dominique Bailey, Takeo Hara, Julian A. Abrams, Kathryn E. Hamilton, Yuta Kasagi, Veronique Giroux, Hiroshi Nakagawa, Jonathan M. Spergel, Gary W. Falk, Amanda B. Muir, Tatiana A. Karakasheva, Seema S. Aceves, Kelly A. Whelan, Takashi Kijima, Benjamin J. Wilkins
Publikováno v:
Curr Protoc Stem Cell Biol
The homeostatic proliferation-differentiation gradient in the esophageal epithelium is perturbed under inflammatory disease conditions such as gastroesophageal reflux disease and eosinophilic esophagitis. Herein we describe the protocols for rapid ge
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 4, Pp 461-478 (2018)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The stratified squamous epithelium of the esophagus shows a proliferative basal layer of keratinocytes that undergo terminal differentiation in overlying suprabasal layers. Esophageal pathologies, including eosinophilic esophagitis, gastroesophageal
Autor:
Dorottya Laczkó, Divya Rao, Khvaramze Shaverdashvili, Kelly A. Whelan, Amanda B. Muir, Daniel Weinblatt, Wenpeng Jiang, Jennie Padlo, Jonathan P. Katz, Yang Jia, John P. Lynch
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215746 (2019)
Understanding the regulatory mechanisms within esophageal epithelia is essential to gain insight into the pathogenesis of esophageal diseases, which are among the leading causes of morbidity and mortality throughout the world. The zinc-finger transcr
Autor:
Thomas A.E. Platts-Mills, Lisa A. Spencer, Marion Groetch, Wendy Book, Mirna Chehade, Joshua B. Wechsler, Chris A. Liacouras, Joshua Friedlander, Marc E. Rothenberg, Kara Kliewer, Ting Wen, Amanda B. Muir, Seema S. Aceves, Nirmala Gonsalves, Antonella Cianferoni, Leah C. Kottyan, Jonathan M. Spergel, Edaire Cheng, Evan S. Dellon, Ikuo Hirano
Publikováno v:
The Journal of allergy and clinical immunology, vol 142, iss 1
The Consortium of Eosinophilic Gastrointestinal Diseases and the International Gastrointestinal Eosinophil Researchers organized a day-long symposium at the recent 2018 Annual Meeting of the American Academy of Allergy, Asthma & Immunology, which was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1514cbb7fd21ca6a8c6ecfd14fd1eba
https://europepmc.org/articles/PMC6129859/
https://europepmc.org/articles/PMC6129859/
Autor:
Glenn T. Furuta, Jamie Merves, Jonathan M. Spergel, Gary W. Falk, Alain Benitez, Amanda B. Muir, Hiroshi Nakagawa, Kelly A. Whelan, Mei-Lun Wang
Publikováno v:
American Journal of Gastroenterology. 111:151-153
Autor:
Medha Sharma, Veronique Giroux, Alain Benitez, Kathryn E. Hamilton, Anil K. Rustgi, Joshua Wang, Kelly A. Whelan, Andres J. Klein-Szanto, Jonathan M. Spergel, Hiroshi Nakagawa, Gary W. Falk, Prasanna M. Chandramouleeswaran, John W. Tobias, Amanda B. Muir, Koji Tanaka, Maureen DeMarshall, Yuta Kasagi
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 333-352 (2018)
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 333-352 (2018)
Background & Aims Aberrations in the esophageal proliferation-differentiation gradient are histologic hallmarks in eosinophilic esophagitis (EoE) and gastroesophageal reflux disease. A reliable protocol to grow 3-dimensional (3D) esophageal organoids
Autor:
Rebecca G. Wells, Gary W. Falk, Daniel A. Hammer, Kelly A. Whelan, Hiroshi Nakagawa, Dale Lee, Alain Benitez, Steven J. Henry, Maureen DeMarshall, Mei-Lun Wang, Kara K. Dods, Amanda B. Muir, Jonathan M. Spergel
Objectives: Eosinophilic esophagitis (EoE) is an immune-mediated allergic disease characterized by progressive esophageal dysmotility and fibrotic stricture associated with chronic esophageal fibroblast activation. It remains unknown how esophageal f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd643199fb942df0fe4715f2f6d65829
https://europepmc.org/articles/PMC4929044/
https://europepmc.org/articles/PMC4929044/
The prevalence of allergic conditions has continuously increased in the last few decades in Westernized countries. A dysbiotic gut microbiome may play an important role in the development of allergic diseases. Genetic, environmental, and dietary fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cc64f6c1cbd25a8d9c80099e248a54
https://europepmc.org/articles/PMC4976690/
https://europepmc.org/articles/PMC4976690/