Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Afd Biomol.Mass Spect. and Proteomics"'
Autor:
Bauzá-Martinez, Julia, Heck, Albert J R, Wu, Wei, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology, 4(1), 1. Springer Nature
Communications Biology
Communications Biology, 4(1), 1. Springer Nature
Communications Biology
Extracellular vesicles can modulate diverse processes ranging from proliferation and tissue repair, to chemo-resistance and cellular differentiation. With the advent of tissue and immunological targeting, extracellular vesicles are also increasingly
Autor:
Bartok, Osnat, Pataskar, Abhijeet, Nagel, Remco, Laos, Maarja, Goldfarb, Eden, Hayoun, Deborah, Levy, Ronen, Körner, Pierre-Rene, Kreuger, Inger Z M, Champagne, Julien, Zaal, Esther A, Bleijerveld, Onno B, Huang, Xinyao, Kenski, Juliana, Wargo, Jennifer, Brandis, Alexander, Levin, Yishai, Mizrahi, Orel, Alon, Michal, Lebon, Sacha, Yang, Weiwen, Nielsen, Morten M, Stern-Ginossar, Noam, Altelaar, Maarten, Berkers, Celia R, Geiger, Tamar, Peeper, Daniel S, Olweus, Johanna, Samuels, Yardena, Agami, Reuven, Dep Scheikunde, Veterinaire biochemie, Sub Biomol.Mass Spect. and Proteomics, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., dB&C FR-RMSC RMSC, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Nature, 590(7845). Nature Research
Nature, 590(7845), 332-337. Nature Publishing Group
Nature
Nature, 590(7845), 332-337. Nature Publishing Group
Nature
Extensive tumour inflammation, which is reflected by high levels of infiltrating T cells and interferon-γ (IFNγ) signalling, improves the response of patients with melanoma to checkpoint immunotherapy1,2. Many tumours, however, escape by activating
Autor:
Sturm, Theo, Sautter, Benedikt, Wörner, Tobias P, Stevanović, Stefan, Rammensee, Hans-Georg, Planz, Oliver, Heck, Albert J R, Aebersold, Ruedi, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Journal of Proteome Research
Journal of Proteome Research, 20 (1)
Journal of Proteome Research, 20(1), 289. American Chemical Society
Journal of Proteome Research, 20 (1)
Journal of Proteome Research, 20(1), 289. American Chemical Society
To understand and treat immunology-related diseases, a comprehensive, unbiased characterization of major histocompatibility complex (MHC) peptide ligands is of key importance. Preceding the analysis by mass spectrometry, MHC class I peptide ligands a
Autor:
Demmers, Laura C., Kretzschmar, Kai, Van Hoeck, Arne, Bar-Epraïm, Yotam E., van den Toorn, Henk W.P., Koomen, Mandy, van Son, Gijs, van Gorp, Joost, Pronk, Apollo, Smakman, Niels, Cuppen, Edwin, Clevers, Hans, Heck, Albert J.R., Wu, Wei, Biomolecular Mass Spectrometry and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Afd Biomol.Mass Spect. and Proteomics
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Tumor heterogeneity is a major cause of therapeutic resistance. Immunotherapy may exploit alternative vulnerabilities of drug-resistant cells, where tumor-specific human leukocyte antigen (HLA) peptide ligands are promising leads to invoke targeted a
Autor:
van der Zwet, Jordy C.G., Buijs-Gladdines, Jessica G.C.A.M., Cordo’, Valentina, Debets, Donna O., Smits, Willem K., Chen, Zhongli, Dylus, Jelle, Zaman, Guido J.R., Altelaar, Maarten, Oshima, Koichi, Bornhauser, Beat, Bourquin, Jean Pierre, Cools, Jan, Ferrando, Adolfo A., Vormoor, Josef, Pieters, Rob, Vormoor, Britta, Meijerink, Jules P.P., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Leukemia, 35(12), 3394. Nature Publishing Group
(Patho-)physiological activation of the IL7-receptor (IL7R) signaling contributes to steroid resistance in pediatric T-cell acute lymphoblastic leukemia (T-ALL). Here, we show that activating IL7R pathway mutations and physiological IL7R signaling ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e418a40b30a03894d9599ac2ab66db4
https://dspace.library.uu.nl/handle/1874/417571
https://dspace.library.uu.nl/handle/1874/417571
Autor:
Pancholi, Sunil, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Nikitorowicz-Buniak, Joanna, Ressa, Anna, Gao, Qiong, Leal, Mariana Ferreira, Bhamra, Amandeep, Thornhill, Allan, Morisset, Ludivine, Montaudon, Elodie, Sourd, Laura, Fitzpatrick, Martin, Altelaar, Maarten, Johnston, Stephen R, Marangoni, Elisabetta, Dowsett, Mitch, Martin, Lesley-Ann, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Oncogene, 39(25), 4781. Nature Publishing Group
Oncogene
Oncogene
Combination of CDK4/6 inhibitors and endocrine therapy improves clinical outcome in advanced oestrogen receptor (ER)-positive breast cancer, however relapse is inevitable. Here, we show in model systems that other than loss ofRB1few gene-copy number
Autor:
Dingess, Kelly A, Gazi, Inge, van den Toorn, Henk W P, Mank, Marko, Stahl, Bernd, Reiding, Karli R, Heck, Albert J R, Afd Biomol.Mass Spect. and Proteomics, Afd Pharmacology, Afd Chemical Biology and Drug Discovery, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics, Pharmacology, Chemical Biology and Drug Discovery
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8140, p 8140 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 15; Pages: 8140
International Journal of Molecular Sciences, 22(15). MDPI AG
International Journal of Molecular Sciences; Volume 22; Issue 15; Pages: 8140
International Journal of Molecular Sciences, 22(15). MDPI AG
Human milk is a vital biofluid containing a myriad of molecular components to ensure an infant’s best start at a healthy life. One key component of human milk is β-casein, a protein which is not only a structural constituent of casein micelles but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83128123d49ae9e3ffd543255dd18bbb
https://dspace.library.uu.nl/handle/1874/412807
https://dspace.library.uu.nl/handle/1874/412807
Autor:
Armony, Gad, Heck, Albert J R, Wu, Wei, Sub Biomol.Mass Spectrometry & Proteom., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Molecular Immunology, 136, 16. Elsevier
Human Leukocyte Antigen (HLA) complexes are critical cell-surface protein assemblies that facilitate T-cell surveillance of almost all cell types in the body. While T-cell receptor binding to HLA class I and class II complexes is well-described with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92fab365b656cbc1b707556ee9e5428
https://dspace.library.uu.nl/handle/1874/412254
https://dspace.library.uu.nl/handle/1874/412254
Autor:
van Keulen, Britt J, Romijn, Michelle, Bondt, Albert, Dingess, Kelly A, Kontopodi, Eva, van der Straten, Karlijn, den Boer, Maurits A, Burger, Judith A, Poniman, Meliawati, Bosch, Berend J, Brouwer, Philip J M, de Groot, Christianne J M, Hoek, Max, Li, Wentao, Pajkrt, Dasja, Sanders, Rogier W, Schoonderwoerd, Anne, Tamara, Sem, Timmermans, Rian A H, Vidarsson, Gestur, Stittelaar, Koert J, Rispens, Theo T, Hettinga, Kasper A, van Gils, Marit J, Heck, Albert J R, van Goudoever, Johannes B, Sub Biomol.Mass Spectrometry & Proteom., Afd Biomol.Mass Spect. and Proteomics, Virologie, dI&I I&I-1, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
van Keulen, B J, Romijn, M, Bondt, A, Dingess, K A, Kontopodi, E, van der Straten, K, den Boer, M A, Burger, J A, Poniman, M, Bosch, B J, Brouwer, P J M, de Groot, C J M, Hoek, M, Li, W, Pajkrt, D, Sanders, R W, Schoonderwoerd, A, Tamara, S, Timmermans, R A H, Vidarsson, G, Stittelaar, K J, Rispens, T T, Hettinga, K A, van Gils, M J, Heck, A J R & van Goudoever, J B 2021, ' Human milk from previously covid-19-infected mothers: The effect of pasteurization on specific antibodies and neutralization capacity ', Nutrients, vol. 13, no. 5, 1645 . https://doi.org/10.3390/nu13051645
Nutrients, 13(5)
Nutrients, Vol 13, Iss 1645, p 1645 (2021)
Nutrients, 13(5):1645. Multidisciplinary Digital Publishing Institute (MDPI)
Nutrients
Volume 13
Issue 5
Nutrients, 13(5), 1. MDPI AG
Nutrients 13 (2021) 5
Nutrients, 13(5)
Nutrients, Vol 13, Iss 1645, p 1645 (2021)
Nutrients, 13(5):1645. Multidisciplinary Digital Publishing Institute (MDPI)
Nutrients
Volume 13
Issue 5
Nutrients, 13(5), 1. MDPI AG
Nutrients 13 (2021) 5
Background: Since the outbreak of coronavirus disease 2019 (COVID-19), many put their hopes in the rapid availability of effective immunizations. Human milk, containing antibodies against syndrome coronavirus 2 (SARS-CoV-2), may serve as means of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08b4a6ddbf5e51085a4b498b2ff6415
https://research.vumc.nl/en/publications/f0275a58-9393-4689-a83c-a01aa6625143
https://research.vumc.nl/en/publications/f0275a58-9393-4689-a83c-a01aa6625143
Autor:
Wörner, Tobias P, Bennett, Antonette, Habka, Sana, Snijder, Joost, Friese, Olga, Powers, Thomas, Agbandje-McKenna, Mavis, Heck, Albert J R, Sub Biomol.Mass Spectrometry & Proteom., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications
Adeno-associated viruses (AAVs) are increasingly used as gene therapy vectors. AAVs package their genome in a non-enveloped T = 1 icosahedral capsid of ~3.8 megaDalton, consisting of 60 subunits of 3 distinct viral proteins (VPs), which vary only in