Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Quansheng Zhou"'
Autor:
Mengli Zhang, Di Yu, Bin Zhang, Zhifei Cao, Pan Zhang, Zhe Zhao, Shijie Tan, Chunping Lv, Quansheng Zhou
Publikováno v:
Toxicology and Applied Pharmacology. 365:1-8
Lung cancer is a leading lethal disease with a 5-year survival rate of only 16%. Inadequate potent anti-cancer drugs appear to be a bottleneck in the treatment of lung cancer; hence, how to develop effective anti-lung cancer therapeutics is an urgent
Autor:
Zhe Zhao, Tong Zhang, Yingnan Qiao, Mei Meng, Jindan Qi, Xiaohua Wang, Bin Zhang, Quansheng Zhou, Shijie Tan, Mengli Zhang
Publikováno v:
Biochemical Pharmacology. 185:114423
Metastatic melanoma has a very high mortality rate despite the availability of chemotherapy, radiotherapy, and immunotherapy; therefore, more effective therapeutics are needed. The Hippo pathway plays an inhibitory role in melanoma progression, but t
Publikováno v:
Toxicology Letters. 278:9-17
Lyn is a proto-oncogene overexpressed and constitutively activated in lymphoma, and plays an important role in lymphoma initiation and malignant progression. Hence, the oncogenic Lyn has recently been targeted for novel anti-lymphoma drug discovery;
Publikováno v:
Toxicology and applied pharmacology. 388
Gastric cancer ranks as the third leading cause of cancer-related death worldwide. The uncontrolled tumor growth and robust metastasis are key factors to cause the cancer patient death. Mechanistically, aberrant activation of Notch and NF-κB signali
Autor:
Mei Meng, Zhifei Cao, Xing-dong Xu, Zhe Zhao, Quansheng Zhou, Tong Zhang, Bowen Chen, Ping Yang, Ye Li, Bin Zhang, Shufen Xiang
Publikováno v:
Biochemical pharmacology. 166
The mitogen-activated protein kinase (MAPK, 1K) family members ERK, JNK, and p38 play a divergent role in either promoting tumorigenesis or tumor-suppression. Activation of ERK and JNK promotes tumorigenesis; whereas, escalation of p38 inhibits carci
Publikováno v:
Biochemical Pharmacology. 104:8-18
Gastric cancer is ranked as the third leading cause of cancer-related death in the world. Although extensive efforts have been made in recent decades to treat gastric cancer with various anticancer drugs, effective anti-gastric cancer therapeutics to
Publikováno v:
Journal of cellular physiology. 234(7)
Metastatic melanoma accounts for 60% of death for skin cancer. Although great efforts have been made to treat the disease, effective drugs against metastatic melanoma still lack at the clinical setting. In the current study, we found that lycorine, a